Development of a Group A Meningococcal Conjugate Vaccine, MenAfriVac™
Group A meningococcal disease has been an important public health problem in sub-Saharan Africa for over a century. From 2003 to 2009 a monovalent group A conjugate vaccine, MenAfriVac™, was developed through an innovative public/private partnership. This article, published in Human Vaccines & Immunotherapeutics, summarizes the laboratory and clinical studies leading to prequalification of MenAfriVac™. The vaccine was introduced in Burkina Faso, Mali, and Niger in December 2010, and the 2011 epidemic season ended with no reported cases of group A meningitis in vaccinated individuals.
Author: Frasch C, Preziosi M-P, LaForce FM
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Citation: Frasch C, Preziosi M-P, LaForce FM. Development of a Group A Meningococcal Conjugate Vaccine, MenAfriVac™. Human Vaccines & Immunotherapeutics. 2012;8(6):715-724.
Resource types: Peer-reviewed journal