Issues and Challenges in the Development of Pneumococcal Protein Vaccines
In view of the increasing licensure and use of pneumococcal conjugate vaccines, the relatively high cost, and growing issues with serotype emergence, there is a need to re-evaluate the role of pneumococcal protein vaccines (PPVs) and pathways to their licensure. This paper, published in Expert Review of Vaccines, summarizes the discussion and viewpoints from an expert meeting regarding the development of PPVs. A wide spectrum of pneumococcal vaccine researchers, developers, and regulators met to review the state of PPVs, identify research and development needs, and provide consensus opinions to support the introduction of new PPVs where possible. They also discussed clinical and regulatory aspects pertinent to these vaccines and generated a series of recommendations for moving the field forward. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)
Author(s): Ginsburg AS, Nahm MH, Khambaty FM, Alderson MR
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Citation: Ginsburg AS, Nahm MH, Khambaty FM, Alderson MR. Issues and Challenges in the Development of Pneumococcal Protein Vaccines. Expert Review of Vaccines. 2012;11(3):279-285.