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Pneumococcal Disease Manifestation in Children Before and After Vaccination: What's New?

This article, published in Vaccine, asserts that contrary to the common belief held by many pediatricians, the most important pneumococcal infections are of the respiratory tract and not invasive diseases. The authors explain that development of newer and more specific diagnostic markers to distinguish bacterial and viral pneumonia would minimize inappropriate diagnosis of false positive cases and treatment with antibacterial agents, while increasing positive predictive values for diagnosis of bacterial pneumonia. These markers will be especially pertinent after the introduction of pneumococcal conjugate vaccines with expanded serotypes, providing coverage against antibiotic-resistant strains. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Andrade AL, Toscano CM, Minamisava R, Costa PS, Andrade JG

Published: 2011

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(Located at www.sciencedirect.com)

Citation: Andrade AL, Toscano CM, Minamisava R, Costa PS, Andrade JG. Pneumococcal Disease Manifestation in Children Before and After Vaccination: What's New? Vaccine. 2011;29(Supplement 3):C2-C14.

Resource types: Peer-reviewed journal

Diseases/vaccines: Pneumococcus

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Global