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Global Burden of Respiratory Infections Due to Seasonal Influenza in Young Children: A Systematic Review and Meta-analysis

This article, published in The Lancet, details a systematic review and meta-analysis to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than five years of age. Based on the findings, the authors estimate that 28,000 to 111,500 children younger than five years old died due to causes attributable to influenza-associated acute lower respiratory infections (ALRI) in 2008, with 99 percent of these deaths occurring in developing countries. Overall, the research showed influenza to be a common pathogen identified in children with ALRI and to constitute a substantial burden on health services around the world. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Nair H, Brooks WA, Katz M, et al.

Published: 2011

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(Located at www.thelancet.com)

Citation: Nair H, Brooks WA, Katz M, et al. Global Burden of Respiratory Infections Due to Seasonal Influenza in Young Children: A Systematic Review and Meta-analysis. The Lancet. 2011;378(9807):1917-1930.

Resource types: Peer-reviewed journal

Diseases/vaccines: Influenza

Topics: Disease burden and surveillance

Regions: Global