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Field Evaluation of a Respiratory Syncytial Virus Vaccine and a Trivalent Parainfluenza Virus Vaccine in a Pediatric Population

This article, published the American Journal of Epidemiology, describes a field study conducted in California, United States, that evaluated two formalin inactivated respiratory virus vaccines, a respiratory syncytial virus (RSV) vaccine and a trivalent parainfluenza vaccine, in a pediatric population from 1966 to 1967. Study results showed neither vaccine to elicit a protective effect. Infants naturally infected with RSV post-vaccination with the RSV vaccine tended to have more severe clinical illness than infants that did not receive the vaccine. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Chin J, Magoffin RL, Shearer LA, Schieble JH, Lennette EH

Published: 1969

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(Located at aje.oxfordjournals.org)

Citation: Chin J, Magoffin RL, Shearer LA, Schieble JH, Lennette EH. Field Evaluation of a Respiratory Syncytial Virus Vaccine and a Trivalent Parainfluenza Vaccine in a Pediatric Population. American Journal of Epidemiology. 1969;89(4):449-463.

Resource types: Peer-reviewed journal

Diseases/vaccines: Respiratory syncytial virus (RSV)

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: North America and Europe