Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine
This article, published in Clinical and Vaccine Immunology, describes research conducted at Children’s Hospital Boston which showed that killing cells of a noncapsulated strain of Streptococcus pneumoniae with chloroform, tricholorethylene, or beta-propiolactone contributed to the protectiveness of a pneumococcal whole-cell vaccine candidate in preclinical studies.
Author(s): Lu Y-J, Yadav P, Clements JD, et al.
Published: 2010
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(Located at cvi.asm.org)
Citation: Lu Y-J, Yadav P, Clements JD, et al. Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine. Clinical and Vaccine Immunology. 2010;17(6):1005-1012.
Resource types: Peer-reviewed journal
Diseases: Pneumococcus
Topics: Disease/vaccine specific information
Regions: Global
