Rotavirus Infections and Vaccines: Burden of Illness and Potential Impact of Vaccination

This article, published in Pediatric Drugs, reviews the current status of rotavirus disease burden and vaccination coverage and effectiveness in the developed and developing worlds. The authors conclude that a successful rotavirus vaccination program will rely upon sustained vaccine efficacy against diverse and evolving rotavirus strains and efficient vaccine delivery systems. The potential introduction of rotavirus vaccines into the world's poorest countries with the greatest rates of rotavirus-related mortality is expected to be very cost effective, while rotavirus vaccines should also be cost effective by international standards when incorporated into developed countries' immunization schedules. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author(s): Grimwood K, Lambert SB, Milne RJ

Published: 2010

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    Citation: Grimwood K, Lambert SB, Milne RJ. Rotavirus Infections and Vaccines: Burden of Illness and Potential Impact of Vaccination. Pediatric Drugs. 2010;12(4):235-256.