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Total results with these characteristics: 385

Topic: Vaccine safety and performance

Page 4 of 20
Effectiveness of Meningococcal Serogroup C Vaccine Programmes

Since the introduction of monovalent meningococcal serogroup C (MenC) glycoconjugate (MCC) vaccines and the implementation of national vaccination programs, the incidence of MenC disease has declined markedly as a result of effective short-term …

Author: Borrow R, Abad R, Trotter C, van der Kils FRM, Vazquez JA

Publication date: 2013

Effectiveness of Monovalent Human Rotavirus Vaccine Against Admission to Hospital for Acute Rotavirus Diarrhoea in South African Children: A Case-Control Study

This study, published in The Lancet Infectious Diseases, examined the effectiveness of rotavirus vaccine in an African setting with a high prevalence of HIV infection. The findings showed that human rotavirus vaccine provided sustained protection …

Author: Groome MJ, Page N, Cortese MM, et al.

Publication date: 2014

Effectiveness of Monovalent Rotavirus Vaccine in Bolivia: Case-Control Study

This article, published in BMJ, reports on a study that evaluated the effectiveness of two doses of a monovalent rotavirus vaccine against hospital admission for rotavirus at six hospitals in Bolivia, between March 2010 and June 2011. Results show …

Author: Patel MM, Patzi M, Pastor D, et al.

Publication date: 2013

Effectiveness of Pentavalent and Monovalent Rotavirus Vaccines in Concurrent Use Among US Children <5 Years of Age, 2009–2011

This article, published in Clinical Infectious Diseases, summarizes a study that assessed vaccine effectiveness of RotaTeq (RV5; 3 doses) and Rotarix (RV1; 2 doses) at reducing rotavirus acute gastroenteritis inpatient and emergency department (ED) …

Author: Payne DC, Boom JA, Staat MA, et al.

Publication date: 2013

Effectiveness of Rotavirus Vaccine Against Hospital Admission for Rotavirus Diarrhoea in Brazilian Children: A Case-Control Study

This meeting abstract, published in The Lancet, shares the results of a study on the effectiveness of rotavirus vaccine to prevent rotavirus hospitalizations among infants in Brazil. The authors found that two doses of the vaccine were highly …

Author: Ichihara MYT, Rodrigues LC, Santos CAST, et al.

Publication date: 2014

Effectiveness of the 13-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in South African Children: A Case-Control Study

This article, published in The Lancet Global Health, reports the results of a study that assessed the effectiveness of two or more doses of 13-valent pneumococcal conjugate vaccine (PCV13) against invasive pneumococcal disease in children with HIV …

Author: Cohen C, von Mollendorf C, de Gouveia L, et al.

Publication date: 2017

Efficacy and Immunogenicity of a Vi-Tetanus Toxoid Conjugate Vaccine in the Prevention of Typhoid Fever Using a Controlled Human Infection Model of Salmonella Typhi: A Randomised Controlled, Phase 2b Trial

This article, published in The Lancet, reports the results of a study to assess the efficacy of a Vi-tetanus toxoid typhoid conjugate vaccine using a human challenge model of typhoid fever. The authors found the vaccine to be well tolerated, highly …

Author: Jin C, Gibani MM, Moore M, et al.

Publication date: 2017

Efficacy and Safety of Human Papillomavirus Vaccine for Primary Prevention of Cervical Cancer: A Review of Evidence From Phase III Trials and National Programs

This article, published in the South Asian Journal of Cancer, discusses the justification of human papillomavirus (HPV) vaccination in the backdrop of the natural history of cervical cancer, the mechanism of action of the vaccines, and efficacy and …

Author: Basu P, Banerjee D, Singh P, Bhattacharya C, Biswas J

Publication date: 2013

Efficacy and Safety of RTS,S/AS01 Malaria Vaccine With or Without a Booster Dose in Infants and Children in Africa: Final Results of a Phase 3, Individually Randomized, Controlled Trial

This article, published in The Lancet, reports the results of a study on the efficacy and safety of the RTS,S/AS01 candidate malaria vaccine. The authors conclude that RTS,S/AS01 prevented a substantial number of cases of clinical malaria over a …

Author: RTS,S Clinical Trials Partnership

Publication date: 2015

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine During 18 Months After Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

This article, published in PLoS Medicine, reports on follow-up data from a Phase 3 trial conducted to test the effectiveness of the malaria vaccine candidate RTS,S/AS01 in children and young infants. RTS,S/AS01 prevented many cases of clinical and …

Author: RTS,S Clinical Trials Partnership

Publication date: 2014

Efficacy and Safety of Vi-Tetanus Toxoid Conjugated Typhoid Vaccine (PedaTyph™) in Indian Children: School Based Cluster Randomized Study

This article, published in Human Vaccines & Immunotherapeutics, reports the results of a study that evaluated the safety and efficacy of a typhoid conjugate vaccine in children 6 months to 12 years of age. The authors found that the vaccine was …

Author: Mitra M, Shah N, Ghosh A, et al.

Publication date: 2016

Efficacy of a Low-Cost, Heat-Stable Oral Rotavirus Vaccine in Niger

This article, published in the New England Journal of Medicine, reports the results of a Phase 3 trial to assess the efficacy and safety of a heat-stable, live, oral bovine rotavirus pentavalent vaccine (BRV-PV) against severe rotavirus …

Author: Isanaka S, Guindo O, Langendorf C, et al.

Publication date: 2017

Efficacy of a Monovalent Human-Bovine (116E) Rotavirus Vaccine in Indian Infants: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, reports on the results of a Phase 3 study to assess the efficacy and tolerability of a monovalent human-bovine rotavirus vaccine (116E) for severe rotavirus gastroenteritis in low-resource urban and rural …

Author: Bhandari N, Rongsen-Chandola T, Bavdekar A, et al.

Publication date: 2014

Efficacy of a Novel, Protein-Based Pneumococcal Vaccine Against Nasopharyngeal Carriage of Streptococcus pneumoniae in Infants: A Phase 2, Randomized, Controlled, Observer-Blind Study

This article, published in Vaccine, assessed the efficacy of two formulations of a pneumococcal vaccine candidate against nasopharyngeal carriage (NPC) prevalence in infants in The Gambia. It examined the impact of the two vaccine formulations on …

Author: Odutola A, Ota MOC, Antonio M, et al.

Publication date: 2017

Efficacy of Fewer Than Three Doses of an HPV-16/18 AS04-Adjuvanted Vaccine: Combined Analysis of Data From the Costa Rica Vaccine and PATRICIA Trials

This article, published in The Lancet Oncology, reports on a study to evaluate the efficacy of fewer than the recommended three doses of human papillomavirus (HPV)-16/18 vaccine four years after vaccination. The authors found that one and two doses …

Author: Kreimer AR, Struyf F, Del Rosario-Raymundo MR, et al.

Publication date: 2015

Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

This article, published in the New England Journal of Medicine, details a study to evaluate if a high dose (60 µg of hemagglutinin per strain) of trivalent, inactivated influenza vaccine (IIV3) improves protection against laboratory-confirmed …

Author: DiazGranados CA, Dunning AJ, Kimmel M, et al.

Publication date: 2014

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Publication date: 2007

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Publication date: 2013

Efficacy, Safety, and Immunogenicity of the Human Papillomavirus 16/18 AS04-Adjuvanted Vaccine in Women Older Than 25 Years: 4-Year Interim Follow-Up of the Phase 3, Double-Blind, Randomised Controlled VIVIANE Study

This article, published in The Lancet, discusses the results of an efficacy, safety, and immunogenicity study of the human papillomavirus (HPV) 16/18 vaccine in adult women. The results showed that in women older than 25 years, the HPV 16/18 vaccine …

Author: Skinner SR, Szarewski A, Romanowski B, et al.

Publication date: 2014

Estimation of the Potential Overall Impact of Human Papillomavirus Vaccination on Cervical Cancer Cases and Deaths

This article, published in Vaccine, reports on a study that aimed to estimate the potential real-life impact of the AS04-adjuvanted HPV-16/18 vaccine on cervical cancer cases and deaths at the country level. The authors found that HPV vaccination …

Author: Van Kriekinge G, Castellsagué X, Cibula D, Demarteau N

Publication date: 2014

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