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Total results with these characteristics: 388

Topic: Vaccine safety and performance

Page 16 of 20
Safety and Immunogenicity of a Novel Influenza Subunit Vaccine Produced in Mammalian Cell Culture

This article, published in the Journal of Infectious Diseases, describes a novel cell culture-derived influenza vaccine (CCIV) produced in Madin-Darby canine kidney cells. The Phase 3, multicenter study in Poland observed that CCIV was well …

Author: Szymczakiewicz-Multanowska A, Groth N, Bugarini R, et al.

Publication date: 2009

Safety and Immunogenicity of a Parenteral P2-VP8-P[8] Subunit Rotavirus Vaccine in Toddlers and Infants in South Africa: A Randomised, Double-Blind, Placebo-Controlled Trial

Low-income countries in Africa and Asia have the highest burden of rotavirus disease, but live oral rotavirus vaccines have shown reduced efficacy in these countries compared with high-income countries. This article, published in the Lancet …

Author: Groome MJ, Koen A, Fix A, et al.

Publication date: 2017

Safety and Immunogenicity of a Parenterally Administered Rotavirus VP8 Subunit Vaccine in Healthy Adults

This article, published in Vaccine, reports on a study to evaluate the safety and immunogenicity of a non-replicating rotavirus vaccine candidate. The authors found that the vaccine was well-tolerated in healthy adults and evoked promising immune …

Author: Fix AD, Harro C, McNeal M, et al.

Publication date: 2015

Safety and Immunogenicity of a Vi Polysaccharide–Tetanus Toxoid Conjugate Vaccine (Typbar-TCV) in Healthy Infants, Children, and Adults in Typhoid Endemic Areas: A Multicenter, 2-Cohort, Open-Label, Double-Blind, Randomized Controlled Phase 3 Study

This article, published in Clinical Infectious Diseases, reports the results of a study examining the safety and efficacy of a typhoid conjugate vaccine in people aged 6 months to 24 years conducted at eight trial sites in India. The results showed …

Author: Mohan VK, Varanasi V, Singh A, et al.

Publication date: 2015

Safety and Immunogenicity of an Improved Oral Inactivated Multivalent Enterotoxigenic Escherichia coli (ETEC) Vaccine Administered Alone and Together with dmLT Adjuvant in a Double-Blind, Randomized, Placebo-Controlled Phase I Study

This article, published in Vaccine, reports on the results of a Phase 1 study of an oral vaccine candidate against enterotoxigenic Escherichia coli (ETEC) administered in combination with a novel mucosal adjuvant, the double-mutant heat-labile toxin …

Author: Lundgren A, Bourgeois L, Carlin N, et al.

Publication date: 2014

Safety and Immunogenicity of Capsular Polysaccharide—Tetanus Toxoid Conjugate Vaccines for Group B Streptococcal Types Ia and Ib

This article, published in the Journal of Infectious Diseases, reports the results of a study to evaluate the safety, immounogenicity, and optimal dose in healthy women of group B Streptococcus (GBS) type Ia- and type Ib-tetanus toxoid (TT) …

Author: Baker CJ, Paoletti LC, Wessels MR, et al.

Publication date: 1999

Safety and Immunogenicity of Concomitant Vaccination With the Cell-Culture Based Japanese Encephalitis Vaccine IC51 and the Hepatitis A Vaccine HAVRIX1440 in Healthy Subjects: A Single-Blind, Randomized, Controlled Phase 3 Study

In travelers often several pre-departure immunizations are indicated, thus data are needed about possible interactions between vaccines. This Phase 3 study investigated the immunogenicity and safety of IC51 (JE vaccine) and HAVRIX1440 (hepatitis A …

Author: Kaltenböck A, Dubischar-Kastner K, Eder G, et al.

Publication date: 2009

Safety and Immunogenicity of Live-Attenuated Japanese Encephalitis SA 14-14-2 Vaccine Co-Administered With Measles Vaccine in 9-Month-Old Infants in Sri Lanka

This article, published in Vaccine, examines the safety and immunogenicity of live attenuated Japanese encephalitis vaccine (LJEV) when administered with measles vaccine in nine-month-old Sri Lankan infants. The results support the use of LJEV at …

Author: Wijesinghe PR, Abeysinghe MRN, Yoksan S, et al.

Publication date: 2014

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine Against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

This article, published in PLoS ONE, shares the results of a Phase 1 trial exploring the safety, immunogenicity, and transmission-blocking activity of a malaria transmission-blocking vaccine candidate, Pfs25-EPA conjugates formulated with …

Author: Talaat KR, Ellis RD, Hurd J, et al.

Publication date: 2016

Safety and Immunogenicity of RTS,S/AS01 Malaria Vaccine in Infants and Children With WHO Stage 1 or 2 HIV Disease: A Randomised, Double-Blind, Controlled Trial

Malaria remains a major global public health concern, especially in sub-Saharan Africa. This article, published in The Lancet Infectious Diseases, reports the results of a study that aimed to assess the safety and immunogenicity of RTS,S/AS01 …

Author: Otieno L, Oneko M, Otieno W, et al.

Publication date: 2016

Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

This study, published in the New England Journal of Medicine, assessed the feasibility of integrating the RTS,S/AS02D malaria vaccine into a standard expanded program on immunization (EPI) schedule for infants. The study, conducted in …

Author: Abdulla S, Oberholzer R, Juma O, et al.

Publication date: 2008

Safety, Immunogenicity, and Antibody Persistence of a New Meningococcal Group A Conjugate Vaccine in Healthy Indian Adults

This article, published in the journal Vaccine, discusses a double-blind, randomized, controlled Phase 1 study in India to assess safety, immunogenicity, and antibody persistence of the new meningococcal group A conjugate vaccine (PsA-TT) …

Author: Kshirsagar N, Mur N, Thatte U, et al.

Publication date: 2007

Safety of Russian-Backbone Seasonal Trivalent, Live-Attenuated Influenza Vaccine in a Phase II Randomized Placebo-Controlled Clinical Trial Among Children in Urban Bangladesh

This article, published in Vaccine, reports the results of a study to evaluate the safety of a Russian-backbone, seasonal trivalent, live-attenuated influenza vaccine (LAIV) in children aged 24 through 59 months in Bangladesh. The authors found that …

Author: Ortiz JR, Goswami D, Lewis KDC, et al.

Publication date: 2015

Safety of the RTS,S/AS02A Malaria Vaccine in Mozambican Children During a Phase IIb Trial

This study, published in the journal Vaccine, evaluated the safety of the RTS,S/AS02A malaria vaccine in a proof of concept Phase IIb trial in Mozambican children aged one to four years. Overall, the study results indicate that the …

Author: Sacarlal J, Aponte JJ, Aide P, et al.

Publication date: 2008

Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review

This article, published in Pediatrics, reviews the existing literature on the safety of routine vaccines recommended for children in the United States. The authors found evidence that some vaccines are associated with serious adverse events; …

Author: Maglione MA, Das L, Raaen L, et al.

Publication date: 2014

Safety Profile of the 9-Valent HPV Vaccine: A Combined Analysis of 7 Phase III Clinical Trials

This article, published in Pediatrics, evaluated the overall safety profile of the 9-valent human papillomavirus (9vHPV) vaccine across seven Phase 3 studies in 9 to 26 year old males and females (nonpregnant at entry). The authors found that the …

Author: Moreira ED, Block SL, Ferris D, et al.

Publication date: 2016

Safety, Tolerability, and Immunogenicity of Pentavalent Rotavirus Vaccine Manufactured by a Modified Process

This article, published in the Pediatric Infectious Disease Journal, describes the results of a Phase 3 study of a modified formulation of RotaTeq® (RV5) rotavirus vaccine that was developed to be stable at 37°C for 7 days and that has an …

Author: Martinón-Torres F, Dionne M, Greenberg D, et al.

Publication date: 2017

The Science of Immunisation: Questions and Answers

This publication aims to address confusion created by contradictory information in the public domain regarding immunization. It sets out to explain the current situation in immunization science, including where there is consensus in the scientific …

Author: Australian Academy of Science

Publication date: 2012

Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015

This article, published in The Journal of Infectious Diseases, examines the antigenic distance hypothesis (AHD) in the context of serial influenza vaccination in Canada. The study found that the effects of repeat influenza vaccination varied …

Author: Skowronski DM, Chambers C, De Serres G, et al.

Publication date: 2017

Significantly Reduced Genoprevalence of Vaccine-Type HPV-16/18 Infections Among Vaccinated Compared to Non-Vaccinated Young Women 5.5 Years After a Bivalent HPV-16/18 Vaccine (Cervarix®) Pilot Project in Uganda

This article, published in PLoS ONE, reports the results of a study that analyzed the prevalence of vaccine and non-vaccine types of human papillomavirus (HPV) infections among bivalent HPV vaccinated and non-vaccinated women aged 15 to 24 years in …

Author: Kumakech E, Berggren V, Wabinga H, et al.

Publication date: 2016

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