This article, published in Vaccine, reviews the most recently developed pneumococcal conjugate vaccines (PCVs) that are now approved for use in children, a 10-valent vaccine and a 13-valent vaccine, as well as other new PCVs in development. In view …

This comment, published in The British Medical Journal, discusses the benefits and risks of rotavirus vaccine for children in developing countries.

This article, published in The Lancet, details how the GAVI Alliance's pilot Advance Market Commitment financing mechanism works to stimulate the manufacture of affordable pneumococcal vaccines for developing countries. ABSTRACT ONLY. (Learn how …

Published in The Lancet, the study aim was to calculate the global burden of disease and risk factors for 2001, to examine regional trends from 1990 to 2001, and to provide a starting point for the analysis of the Disease Control Priorities Project. …

This article, published in The Lancet Infectious Diseases, provides an overview of a systematic review and meta-analysis of published papers from 1998 to 2008 to estimate the risks of major and minor sequelae caused by bacterial meningitis,  …

This article, published in The Lancet, describes research to estimate the global incidence of and mortality from episodes of acute lower respiratory infection (ALRI) due to respiratory syncytial virus (RSV) in children younger than five years …

This article, published in The Lancet, details a systematic review and meta-analysis to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than five years of age. Based on …

This article, published in the journal Vaccine, reviews meningococcal disease epidemiology and its variability across geographic area and time. The review summarizes the current status of meningococcal disease epidemiology by region, but notes that …

This article, published in the Pediatric Infectious Disease Journal, reviews outbreaks of meningococcal disease across the globe and the serotypes associated with these outbreaks. The author also discusses the different vaccines …

This seminal paper, published in Emerging Infectious Diseases, estimates global incidence of rotavirus disease and related deaths, based on a review of studies published 1986–2000.

Over 70 countries developed comprehensive Multi-Year Plans (cMYPs) for implementing the Global Immunization Vision and Strategy (GIVS) for the period 2006 to 2015. This paper, published in Health Policy and Planning, describes the outcomes of a …

Travelers who experience diarrhea are exposed to the same pathogens and illnesses that pose some of the greatest threats to life and development among malnourished children in developing areas around the world, where inadequate water and poor …

The Global Meningococcal Initiative (GMI) is composed of an international group of scientists, clinicians, and public health officials that aim to promote the global prevention of invasive meningococcal disease through education and research. In …

This article, published in Vaccine, summarizes results from a World Health Organization (WHO) survey assessing global influenza vaccine production in the context of the 2009 influenza A (H1N1) pandemic.  The authors compare results …

This article, published in The Lancet, reports new estimates for 2008 of the major causes of death in children younger than five years. The authors estimated proportional causes of death for 193 countries, and by application of these proportions to …

This article, which appeared in Vaccine, details research conducted at Children’s Hospital Boston to determine the performance of subcutaneous injection of pneumococcal whole-cell vaccine in preclinical studies. ABSTRACT ONLY. (Learn how users …

These guidelines, published in the journal Vaccine, seek to standardize vaccine safety assessment by improving the accuracy and completeness of collection, analysis, and presentation of information about Adverse Events Following Immunization in …

Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. This study reviewed …

This study, published in The Journal of Infectious Diseases, estimated economic burden and the vaccination cost-effectiveness ratio to determine potential reductions in health care costs associated with rotavirus-specific diarrhea.

This article, published in Human Vaccines, discusses a study to develop a formulation of recombinant hepatitis B vaccine with improved stability at elevated temperatures. A new vaccine formulation has the potential to be used outside the cold chain …

This article, published in Vaccine, reports on the development of a heat-stable measles vaccine powder using a combination of unique stabilizers and mild spray-drying process conditions. The researchers identified spray drying as the optimal …

This article, published in the Canadian Medical Association Journal, reviews the evidence for long-term effectiveness of vaccination programs for infants and adolescents against hepatitis B. Long-term observational data show that vaccinated …

An empirical quantitative model was developed to estimate the herd (indirect) effects on the incidence of invasive disease among persons ≥5 years of age induced by vaccination of young children with 1, 2, or ≥3 doses of the …

Published in the Journal of Clinical Microbiology, this article examins the burden of diarrheal disease due to enterotoxigenic E. coli among rural Egyptian infants and young children, whic has an incidence of 1.5 episodes per child per …

This editorial, published in the New England Journal of Medicine, discusses the RTS,S vaccine against malaria and the significance of this being the first malaria vaccine to reach an advanced stage of development.