Browse resources

Topic: Disease/vaccine specific information

Total results with these characteristics: 987

Effectively Introducing a New Meningococcal A Conjugate Vaccine in Africa: The Burkina Faso Experience

In 2010, Burkina Faso conducted a country-wide campaign to introduce a new Group A meningococcal conjugate vaccine, MenAfriVac™. Leading up to this effort, the following challenges were successfully managed: (1) conducting a large safety study …

Author: Djingarey MH, Barry R, Bonkoungou M, et al.

Published: 2012

Effectiveness of an Indian-made Attenuated Influenza A(H1N1)pdm 2009 Vaccine: A Case Control Study

This article, published in Human Vaccines & Immunotherapeutics, details a case control study to evaluate the effectiveness of a live attenuated A(H1N1)pdm 2009 vaccine produced by the Serum Institute of India, Ltd., which was distributed in …

Author: Kulkarni PS, Agarkhedkar S, Lalwani S, et al.

Published: 2014

Effectiveness of Haemophilus influenzae type b Conjugate Vaccine on Prevention of Pneumonia and Meningitis in Bangladeshi Children: A Case-Control Study

Few Asian countries have introduced Haemophilus influenzae type b (Hib) conjugate vaccine because of its cost and uncertainty regarding disease burden. To estimate the effectiveness of Hib conjugate vaccine in preventing pneumonia and meningitis in …

Author: Baqui AH, El Arifeen S, Saha SK, et al.

Published: 2007

Effectiveness of Maternal Influenza Immunization in Mothers and Infants

Young infants and pregnant women are at increased risk for serious consequences of influenza infection. Inactivated influenza vaccine is recommended for pregnant women but is not licensed for infants younger than six months of age. This study …

Author: Zaman K, Roy E, Arifeen S, et al.

Published: 2008

Effectiveness of Meningococcal Serogroup C Vaccine Programmes

Since the introduction of monovalent meningococcal serogroup C (MenC) glycoconjugate (MCC) vaccines and the implementation of national vaccination programs, the incidence of MenC disease has declined markedly as a result of effective short-term …

Author: Borrow R, Abad R, Trotter C, van der Kils FRM, Vazquez JA

Published: 2013

Effectiveness of Monovalent Rotavirus Vaccine in Bolivia: Case-Control Study

This article, published in BMJ, reports on a study that evaluated the effectiveness of two doses of a monovalent rotavirus vaccine against hospital admission for rotavirus at six hospitals in Bolivia, between March 2010 and June 2011. Results show …

Author: Patel MM, Patzi M, Pastor D, et al.

Published: 2013

Effectiveness of One Dose of SA 14-14-2 Vaccine Against Japanese Encephalitis

Correspondence, published in the New England Journal of Medicine, about a small case control study in Uttar Pradesh, India, on the efficacy of a single dose of the SA 14-14-2 JE vaccine within six months of its administration. …

Author: Kumar R, Tripathi P, Rizvi A

Published: 2009

Effectiveness of Pentavalent and Monovalent Rotavirus Vaccines in Concurrent Use Among US Children <5 Years of Age, 2009–2011

This article, published in Clinical Infectious Diseases, summarizes a study that assessed vaccine effectiveness of RotaTeq (RV5; 3 doses) and Rotarix (RV1; 2 doses) at reducing rotavirus acute gastroenteritis inpatient and emergency department (ED) …

Author: Payne DC, Boom JA, Staat MA, et al.

Published: 2013

Efficacy and Safety of Human Papillomavirus Vaccine for Primary Prevention of Cervical Cancer: A Review of Evidence From Phase III Trials and National Programs

This article, published in the South Asian Journal of Cancer, discusses the justification of human papillomavirus (HPV) vaccination in the backdrop of the natural history of cervical cancer, the mechanism of action of the vaccines, and efficacy and …

Author: Basu P, Banerjee D, Singh P, Bhattacharya C, Biswas J

Published: 2013

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine During 18 Months After Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

This article, published in PLoS Medicine, reports on follow-up data from a Phase 3 trial conducted to test the effectiveness of the malaria vaccine candidate RTS,S/AS01 in children and young infants. RTS,S/AS01 prevented many cases of clinical and …

Author: RTS,S Clinical Trials Partnership

Published: 2014

Efficacy of a Monovalent Human-Bovine (116E) Rotavirus Vaccine in Indian Infants: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, reports on the results of a Phase 3 study to assess the efficacy and tolerability of a monovalent human-bovine rotavirus vaccine (116E) for severe rotavirus gastroenteritis in low-resource urban and rural …

Author: Bhandari N, Rongsen-Chandola T, Bavdekar A, et al.

Published: 2014

Efficacy of a Pneumococcal Conjugate Vaccine Against Acute Otitis Media

This study, published in the New England Journal of Medicine, enrolled 1662 infants in a randomized, double-blind efficacy trial of a heptavalent pneumococcal polysaccharide conjugate vaccine in which the carrier protein is the nontoxic …

Author: Eskola J, Kilpi T, Palmu A, et al.

Published: 2001

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Published: 2007

Efficacy of Nine-valent Pneumococcal Conjugate Vaccine Against Pneumonia and Invasive Pneumococcal Disease in The Gambia: Randomized Double-Blind, Placebo-Controlled Trial

Published in The Lancet, this study aims to assess the efficacy of a nine-valent pneumococcal conjugate vaccine in children through a randomised, placebo-controlled, double-blind trial in eastern Gambia. Children age 6–51 weeks were randomly …

Author: Cutts U, Zaman SMA, Enwere G, et al.

Published: 2005

Efficacy of Pentavalent Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Infants in Developing Countries in Asia: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, assesses the clinical efficacy of the pentavalent, live oral rotavirus vaccine for the prevention of severe rotavirus gastroenteritis in infants in Bangladesh and Vietnam. Study results demonstrated vaccine …

Author: Zaman K, Dang DA, Victor JC, et al.

Published: 2010

Efficacy of Pentavalent Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Infants in Developing Countries in Sub-Saharan Africa: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, shares results of an efficacy study of the pentavalent, live oral rotavirus vaccine in Ghana, Kenya, and Mali. Results showed 39.3 percent efficacy against  severe rotavirus gastroenteritis. The authors …

Author: Armah GE, Sow SO, Breiman RF, et al.

Published: 2010

Efficacy of Pneumococcal Conjugate Vaccines and Their Effort on Carriage and Antimicrobial Resistance

Pneumococcal conjugate vaccines have shown a high degree of success in preventing pneumococcal bacteraemia in children. They also reduce the acquisition of carriage of vaccine serotypes in the nasopharynx, and reduce otitis media caused by those …

Author: Klugman K

Published: 2001

Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age

This study, published in the New England Journal of Medicine, evaluated the efficacy of the RTS,S malaria vaccine given with a more immunogenic adjuvant system (AS01E) than one used in a previous study (AS02A). The study was conducted in …

Author: Bejon P, Lusingu J, Olotu A, et al.

Published: 2008

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Published: 2013

Efficacy of the Human Rotavirus Vaccine RIX4414 in Malnourished Children

This study, published in the Journal of Infectious Diseases, determined that the Rotarix® vaccine produced by GlaxoSmithKline decreased the incidence severe gastroenteritis caused by rotavirus at comparable rates among well-nourished and …

Author: Perez-Schael I, Salinas B, Tomat M, et al.

Published: 2007

Eliminating Epidemic Group A Meningococcal Meningitis in Africa Through a New Vaccine

This article, published in Health Affairs, discusses a new affordable vaccine against Group A meningococcus, the most common cause of large and often fatal African epidemics of meningitis, that was introduced in Burkina Faso, Mali, and Niger in …

Author: LaForce FM, Okwo-Bele J-M

Published: 2011

Elimination of Haemophilus influenzae type b (Hib) Disease From The Gambia After the Introduction of Routine Immunisation With a Hib Conjugate Vaccine: A Prospective Study

Routine immunization of infants in The Gambia with a Haemophilus influenzae type b (Hib) polysaccharide-tetanus toxoid conjugate vaccine began in May 1997. This article, published in The Lancet, reports on a study that investigated the effectiveness …

Author: Adegbola RA, Secka O, Lahai G, et al.

Published: 2005

E-medicine: Japanese Encephalitis

This article provides a comprehensive overview of the disease.

Author: Kallen A

Published: 2002

Emergence of Serogroup X Meningococcal Disease in Africa: Need for a Vaccine

This article, published in Vaccine, describes how and why serogroup X meningococcal disease has emerged in Africa in recent years. It asserts that while no licensed vaccine is available against serogroup X meningococci, following the introduction of …

Author: Xie O, Pollard AJ, Mueller JE, Norheim G

Published: 2013

Emergency or Routine Vaccination Against Meningococcal Disease in Africa?

This comment, published in The Lancet, is based on a review of the study "Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa." The author concludes that …

Author: Peltola H

Published: 2000