Epidemic meningococcal meningitis remains a serious health threat in the African meningitis belt. New meningococcal conjugate vaccines are relatively costly and their efficiency will depend on cost savings realized from no longer having to respond …

This article, published in Clinical Infectious Diseases, discusses an anthropologic and economic study in Burkina Faso to understand perceptions and behavior relative to meningitis and to determine the cost of illness from bacterial …

Investigators found that rotavirus gastroenteritis incurs considerable use of health care resources and results in substantial costs for families of patients and employers. Routine rotavirus vaccination could significantly reduce the related …

In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …

This document provides details on PATH's partnership with the National Expanded Program on Immunization in Vietnam to enhance surveillance of JE disease and inform future immunization program planning.

Epidemic meningococcal meningitis continues to be an important worldwide cause of morbidity and mortality, especially in developing countries. Throughout its history, a number of "critical episodes" have occurred that have enhanced understanding of …

This article, published in The New England Journal of Medicine, describes a study to assess preexisting immunity in humans to the new pandemic influenza A(H1N1) virus in order to evaluate seasonal vaccine strategies. Researchers used a …

This paper examines the health risks posed by unsafe injections in Africa and outlines some of the programs that are helping reduce these risks.

This issue brief discusses how ensuring swift and efficient HPV vaccine introduction in developing countries will not only help address the burden of cervical cancer, but will also provide a valuable opportunity for AIDS vaccine researchers and …

This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …

This literature review, published in Expert Opinion on Biological Therapy, analyzes use of current JE vaccines and development of alternative vaccine candidates.

From the journal Tropical Medicine and International Health, this summary of surveillance data from Malaysia reveals seasonal peak incidence, age distribution of JE cases, and effect of the JE immunization program on disease incidence.

This website provides information about the DoV Collaboration which was launched in 2010 to enhance coordination across the global community by bringing together diverse stakeholders to develop an evidence-based, country-led global vaccine action …

Published in the New England Journal of Medicine, this study examined population-based data from the Active Bacterial Core Surveillance of the Centers for Disease Control and Prevention to evaluate changes in the burden of invasive disease, defined …

Published in The Lancet, this article assesses the effect of routine infant immunization with seven-valent pneumococcal conjugate vaccine (PCV7) on rates of all-cause and pneumococcal pneumonia admissions. ABSTRACT ONLY. (Learn how users in …

This website provides comprehensive resources on diarrheal disease treatment interventions, including low-osmolarity oral rehydration solution, zinc treatment, and rotavirus vaccines. Traditional interventions such as improved sanitation and …

The epidemiology of meningococcal meningitis in the African meningitis belt is characterized by seasonality, localized epidemics, and epidemic waves. To facilitate research and surveillance, the authors of this article, published in BMC Infectious …

This report highlights new partnerships and innovations in cervical cancer prevention and treatment. It also provides profiles of success in increasing access to HPV vaccines and treatment from around the world, with country spotlights on Mexico, …

Project Optimize undertook a cost-comparison case study of five container options for vaccine transport from the national to the regional level in Senegal. This report may be used as a starting point for other country vaccine programs weighing …

This 30-page manual for program managers helps guide decision-making related to safe syringe disposal at the district level. A range of disposal methods and issues are covered, including practical advice on incineration (with details on two small …

This article, published in Procedia in Vaccinology, discusses the importance of designing vaccines with traits that will minimize complications for immunization programs and increase the likelihood of successful adoption. The article also summarizes …

This article, published in the Journal of Pharmaceutical Sciences, discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including enhanced stability and efficient packaging, that can help to …

This article, published in the World Health Organization's (WHO's) Weekly Epidemiological Record, provides the WHO recommendation for detecting and responding to meningococcal meningitis epidemics in highly-endemic countries in Africa. In each …

Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses …

This paper outlines the role of developing country vaccine manufacturers in global efforts to increase access to vaccines.