To establish a relation between deaths due to acute respiratory infections (ARI) and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence …

This article, published in Influenza and Other Respiratory Viruses, details the results of a meta-analysis conducted to provide insights into the global impact of the 2009 influenza A(H1N1) pandemic. The study estimates overall and age-specific …

Published in The Bulletin of the World Health Organization, this study provides estimates of diarrhea mortality at country, regional, and global levels and discusses interventions to reduce childhood mortality caused by diarrheal disease.

This paper estimates the costs of achieving the Global Immunization Vision and Strategy, 2006 - 2015, which aims to immunize more people, from infants to seniors, with a greater range of vaccines, and whose chief goal is to, by 2015 or earlier, …

Published in the journal Vaccine, this article describes a method for correlating pneumococcal anticapsular antibody responses of infants immunized with pneumococcal conjugate (PnC) vaccine (Prevenar) with clinical protection from invasive …

This article, published in Revista Médica de Chile, outlines an economic model that determined rotavirus vaccination is a cost-effective intervention that can effectively reduce the disease burden and healthcare costs of rotavirus …

This study, published in the Journal of Infectious Diseases, explores the biological plausibility of intussusception caused by natural rotavirus infection.

This article, published in Vaccine, estimates the cost-effectiveness of introducing the rotavirus vaccine RotaTeq® in Ghana. The authors estimated the average costs of treating children with diarrhea in the Ashanti region of Ghana as inpatients …

This article, published in The Journal of Health, Population, and Nutrition, summarizes the general steps required for meningococcal vaccine development, reviews the use of immunogenicity criteria as a licensing strategy for new meningococcal …

This article, published in BMC Public Health, summarizes the results of a literature review and an expert opinion exercise to evaluate the best course of protection against respiratory syncytial virus (RSV) for children in the developing world, …

This study, published in Epidemiology and Infection, evaluated an ecological model based on absolute humidity and land cover type to predict the location of meningitis epidemics in the Sahelian region known as the African Meningitis Belt. The …

From the American Journal of Tropical Medicine and Hygiene, this study evaluates the sensitivity, specificity, and usability of three commercially-available kits for Japanese encephalitis laboratory diagnostics.

This article, from the Philosophical Transactions of the Royal Society B, provides a review of the enteric vaccines currently available and their lack of use in developing countries. The author purports that the reasons for this are multiple and …

Published in The Lancet, this review summarises available data on the burden of pneumococcal disease and the safety and efficacy of PCVs in HIV-infected children. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to …

Since 1993 the Pan American Health Organization has coordinated a surveillance network with the National Reference Laboratories of Argentina, Brazil, Chile, Colombia, Mexico and Uruguay aimed at monitoring capsular types and antimicrobial …

This article, published in Expert Review of Vaccines, discusses morbidity and mortality due to meningococcal serogroups A, C, Y, and W-135 and the ability of monovalent meningococcal serogroup C conjugate (MCC) vaccines to reduce the burden of …

Good cold chain practice is essential to maintain full immunogenicity of vaccines. This article, published in Vaccine, reports on a study that aimed to identify the likelihood and extent of exposure to inappropriate temperatures in the vaccine cold …

This article, published the American Journal of Epidemiology, describes a field study conducted in California, United States, that evaluated two formalin inactivated respiratory virus vaccines, a respiratory syncytial virus (RSV) vaccine and a …

A malaria vaccine, deployed in combination with current malaria-control tools, could play an important role in future control and eventual elimination of malaria in Africa. This article, published in the New England Journal of Medicine (NEJM), …

This article, published in the Journal of Immune Based Therapies and Vaccines, describes preclinical research which demonstrates that a vaccine composed of killed whole cell, nonencapsulated pneumococci and formulated with aluminum hydroxide induces …

This article, published in The New England Journal of Medicine, reports on a clinical trial comparing fractional doses of inactivated poliovirus vaccine administered intradermally with full doses of vaccine given intramuscularly, with respect …

This analysis, published in the journal Vaccine, highlights the pervasiveness of accidental freezing across the cold chain and makes recommendations for addressing the problem. ABSTRACT ONLY. (Learn how users in developing countries can gain free …

This article, published in the Bulletin de la Société de Pathologie Exotique, summarizes an international conference held in Niamey, Niger, that brought together more than 100 delegates to assess the current meningitis situation in Africa, …

This review, published in The Lancet Infectious Diseases, summarizes the role of rotavirus vaccination in reducing childhood hospitalizations and deaths due to severe diarrhea. The authors also highlight insights revealed through routine …

The authors of this article, published in The Lancet, discuss the challenges and possibilities of further expanding coverage of existing vaccines while widely implementing new vaccines, with respect to low-income and middle-income countries. They …