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Topic: Vaccine safety and performance

Total results with these characteristics: 204

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Stability of Vaccines – Bridging From Stability Data to Continuous Safety and Efficacy Throughout Shelf Life – An Always Reliable Approach?

This article, published in Biologicals, discusses why stability studies are important tools to reliably ensure that the efficacy and safety of medicinal products remain unchanged from release of drug product until the end of shelf life. The author …

Author: Pfleiderer M

Published: 2009

State of the World's Vaccines and Immunization, Third Edition

This report focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals. It looks at the development and use of vaccines and the …

Author: World Health Organization, United Nations Children's Fund, World Bank

Published: 2009

Statement Regarding Rotarix and RotaTeq Rotavirus Vaccines and Intussusception

This statement summarizes several post-licensure evaluations on rotavirus vaccines and intussusception that were presented to the US Advisory Committee on Immunization Practices. Some studies performed outside the United States have detected a …

Author: US Centers for Disease Control and Prevention

Published: 2010

Strategic Advisory Group of Experts Recommendations: Rotavirus Vaccination

This issue of the Weekly Epidemiological Record reports on the World Health Organization's Strategic Advisory Group of Experts' recommendation for inclusion of rotavirus vaccines in all national immunization programs. The new …

Author: World Health Organization

Published: 2009

Subunit Influenza Vaccines Produced From Cell Culture or in Embryonated Chicken Eggs: Comparison of Safety, Reactogenicity, and Immunogenicity

This study, published in the Journal of Infectious Diseases, assessed the safety, reactogenicity, and immunogenicity of an injectable cell culture-derived influenza vaccine, compared with those of an injectable egg-based trivalent inactivated …

Author: Reisinger KS, Block SL, Izu A, Groth N, Holmes SJ

Published: 2009

Talking About Vaccines: Vaccine Safety

This web page contains links a number of vaccine safety resources, including websites, journal articles, and fact sheets.

Author: Immunization Action Coalition

Temporal Trends in Diarrhea-Related Hospitalizations and Deaths in Children Under Age 5 Before and After the Introduction of the Rotavirus Vaccine in Four Latin American Countries

This article, published in Vaccine, reports on a study that evaluated trends in diarrhea-related deaths and hospitalizations in children less than five years of age before and after rotavirus vaccine introduction in Bolivia, El Salvador, Honduras, …

Author: De Oliveira LH, Giglio N, Ciapponi A, et al.

Published: 2013

Thimerosal

This web page provides a US Centers for Disease Control and Prevention (CDC) statement on the safety of thimerosal in vaccines and links to CDC and outside resources that provide further information on this topic. 

Author: US Centers for Disease Control and Prevention

Thimerosal in Vaccines

This page contains information on thimerosal, a mercury-containing preservative that has been used in vaccines. The page also includes links to other resources on thimerosal and vaccines.

Author: US Food and Drug Administration

Thiomersal

This information sheet covers issue relating to the use of thiomersal (also known as thimerosal) in vaccines, including why it is used, evidence regarding safety, and the World Health Organization's position on the issue.

Author: World Health Organization

Published: 2011

Thiomersal - Questions and Answers

This in-depth fact sheet provides common questions and answers related to the use of thiomersal (also known as thimerosal) in vaccines. It includes general information about thiomersal, which vaccines contain it and why, updates on additional …

Author: World Health Organization

Published: 2011

Trends in Intussusception Hospitalizations Among US Infants Before and After Implementation of the Rotavirus Vaccination Program, 2000-2009

This article, published in the Journal of Infectious Diseases, reports on surveillance conducted following rotavirus vaccine introduction in 2006 that noted a small increase in intussusception among US infants aged 8 to 11 weeks, who would have …

Author: Yen C, Tate JE, Steiner CA, Cortese MM, Patel MM, Parashar UD

Published: 2012

Trends in National Rotavirus Activity Before and After Introduction of Rotavirus Vaccine into the National Immunization Program in the United States, 2000 to 2012

Rotavirus vaccine introduction in the United States in 2006 led to substantial declines in rotavirus detections during 2007 to 2010. To further evaluate the long-term impact of the vaccine program, the authors of this article, published in the …

Author: Tate JE, Haynes A, Payne DC, et al.

Published: 2013

Understanding Thimerosal, Mercury, and Vaccine Safety

This fact sheet explains what thimerosal is and why it is used as a preservative in some multi-dose vials of influenza vaccine, and highlights conclusions from studies examining thimerosal safety in vaccines.

Author: US Centers for Disease Control and Prevention

Published: 2012

The Vaccine Confidence Project

This project was formed to build a multi-disciplinary network of biomedical scientists, decision scientists, psychologists, and social scientists to examine the influences and decision-making processes as individuals around the world, including …

Author: London School of Hygiene & Tropical Medicine

Vaccine Discovery and Translation of New Vaccine Technology

An unprecedented increase in new vaccine development has occurred over the past three decades. This article, published in The Lancet, discusses new methods of discovery, such as reverse vaccinology, structural biology, and systems biology, which …

Author: Rappuoli R, Black S, Lambert PH

Published: 2011

Vaccine for Prevention of Mild and Moderate-to-Severe Influenza in Children

This article, published in the New England Journal of Medicine, describes a multinational, Phase 3, observer-blinded study evaluating the efficacy of quadrivalent influenza vaccine (QIV) among children three to eight years of age. From the study …

Author: Jain VK, Rivera L, Zama Khalequ, et al.

Published: 2013

Vaccine Information You Need

This website is a comprehensive and user-friendly source of scientifically accurate and easily navigable immunization information. The site offers parents, other adults, legislators, the media, and others a one-stop shop for learning about vaccines …

Author: Immunization Action Coalition

Vaccine Safety

This website offers an overview of vaccine safety issues, addresses common concerns, and provides links to further, more-detailed information.

Author: US Centers for Disease Control and Prevention

Vaccine Safety and Your Child: Separating Fact From Fiction

This 32-page booklet is excerpted from a book published in 2011, and was developed by the Vaccine Education Center of the Children's Hospital of Philadelphia to serve as a resource for parents. Topics covered include: general questions about vaccine …

Author: Offit PA, Moser CA

Published: 2013

Vaccine Safety Basics: E-Learning Course

This online training course aims to establish a shared understanding among professionals whose work is linked to vaccine safety issues. This may include nurses/midwives/community health workers, as well as pharmacists, medical doctors, and program …

Author: World Health Organization

Vaccine Safety Net

While many quality web sites offer science-based information about vaccine safety, others may provide unbalanced and misleading information. This can lead to undue fears, particularly among parents and patients. This web page provides a list of …

Author: World Health Organization

Vaccine-Enhanced Respiratory Syncytial Virus Disease in Cotton Rats Following Immunization with Lot 100 or a Newly Prepared Reference Vaccine

A formalin-inactivated respiratory syncytial virus vaccine was used to immunize infants in the mid-1960s; when these children later were naturally infected by the virus they developed markedly accentuated disease, and two died. For the …

Author: Prince GA, Curtis SJ, Yim KC, Porter DD

Published: 2001

VaccineOrb

This website offers access to the latest vaccine news, papers, and webcasts related to vaccine funding, safety, and trials. The site aims to provide a resource that will enable vaccinologists to be well informed, stimulated, and fascinated by the …

Author: Elsevier

Vaccine-Related Journal Articles

Compiled by the Immunization Action Coalition, this web page provides a chronological compendium of selected peer-reviewed vaccine-related articles. A user can browse by topic areas such as vaccine safety, specific diseases, and people …

Author: Immunization Action Coalition

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