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Total results with these characteristics: 210

Disease: Pneumococcus

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13-Valent Pneumococcal Conjugate Vaccine: A Review of Its Use in Infants, Children, and Adolescents

This article, published in Pediatric Drugs, reviews the use of the 13-valent pneumococcal conjugate vaccine (PCV13) in infants, children, and adolescents. The author states the safety and reactogenicity of PCV13 to be generally similar to that of …

Author: Plosker GL

Publication date: 2013

23-valent Pneumococcal Polysaccharide Vaccine - WHO Position Paper

This report, published in the Weekly Epidemiological Record, provides essential background information on pneumococcal disease and gives the current World Health Organization position concerning the use of the 23-valent …

Author: World Health Organization

Publication date: 2008

Adult Vaccination Resources Library

This online library gathers resources specifically related to adult immunization, providing healthcare providers and the general public with access to relevant resources that can be used in a clinic setting or for individual education. It includes …

Author: Immunization Action Coalition

The Advance Market Commitment Pilot for Pneumococcal Vaccines: Outcomes and Impact Evaluation

This report assesses the extent to which the Advanced Market Commitment (AMC) pilot program has achieved its stated objectives and overarching goal of reducing morbidity and mortality from pneumococcal disease by accelerating the development, …

Author: The Boston Consulting Group

Publication date: 2015

Advancing Vaccines and Immunization Issues, Insights, and Innovations

This supplement of Vaccine contains 16 articles that cover a broad spectrum of important issues in vaccine science, including vaccine safety, efficacy, and implementation. The overarching theme revolves around identifying barriers to vaccination and …

Author: Artenstein AW, Halsey NA, Nowak GJ, eds.

Publication date: 2015

Antibody-Independent, Interleukin-17A-Mediated, Cross-serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide

Published in the journal Infection and Immunity, this article shows that C-Ps given intranasally with mucosal adjuvant increased the resistance of mice to experimental nasopharyngeal colonization by capsulated S. pneumoniae of serotype 6B.

Author: Malley R, Srivastava A, Lipsitch M, et al.

Publication date: 2006

Bacterial Pneumonia Vaccines and Childhood Pneumonia: Are We Winning, Refining, or Redefining?

Published in The Lancet Infectious Diseases, this article provides an overview of the diagnostic challenges of bacterial pneumonia and highlight the need for refining the current diagnostic approach to ensure adequate epidemiological surveillance of …

Author: Obaro S, Madhi S

Publication date: 2006

Beyond Efficacy: The Full Public Health Impact of Vaccines

This conference report, published in Vaccine, describes an active discussion in the public health community on how to assess and incorporate, in addition to safety and measures of protective efficacy, the full public health value of preventive …

Author: Saadatian-Elahi M, Horstick O, Breiman RF, et al.

Publication date: 2016

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein

Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …

Author: Mann B, Thornton J, Heath R, et al.

Publication date: 2013

The Burden of Childhood Pneumonia in the Developed World: A Review of the Literature

This article, published in The Pediatric Infectious Disease Journal, provides disease burden estimates of pneumonia incidence in the developed world in children under five years of age. Available estimates suggest that each year there are up to 2.6 …

Author: Madhi SA, Wals PD, Grijalva CG, et al.

Publication date: 2013

Burden of Disease Caused by Streptococcus Pneumoniae in Children Younger than 5 Years: Global Estimates

This article, published in The Lancet, releases new global burden of disease data for Streptococcus pneumoniae (pneumococcus), a leading cause of bacterial pneumonia, meningitis, and sepsis in children worldwide. The results also include data at the …

Author: O'Brien KL, Wolfson LJ, Watt JP, et al.

Publication date: 2009

The Burden of Pneumococcal Disease Among Latin American and Caribbean Children: Review of the Evidence

This article, published in the Pan American Journal of Public Health, estimates the annual burden of pneumonia, meningitis, and acute otitis media caused by pneumococcus in children less than five years of age in Latin America and the …

Author: Valenzuela MT, O'Loughlin R, De La Hoz F, et al.

Publication date: 2009

The Burden of Pneumococcal Disease and Cost-Effectiveness of a Pneumococcal Vaccine in Latin America and the Caribbean: A Review of the Evidence and a Preliminary Economic Analysis

This report estimates the burden and costs of pneumococcal disease in Latin America and the Caribbean in order to inform national health authorities about disease burden and the economic value of implementing a pneumococcal …

Author: Sabin Vaccine Institute

Publication date: 2007

Can Successful Vaccines Teach Us How to Induce Efficient Protective Immune Responses?

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

Author: Lambert PH, Liu M, Siegrist CA

Publication date: 2005

Center for Vaccine Innovation and Access

This website provides information about the work of PATH’s Center for Vaccine Innovation and Access, which brings together expertise across every stage of vaccine research, development, and introduction to make lifesaving vaccines globally …

Author: PATH

Child Health in Tanzania: Identifying Policy Pathways to Help Prevent Child Deaths From Pneumonia and Diarrhea

This report provides policy recommendations to help Tanzania reduce the impacts of pneumonia and diarrhea, including the use of available vaccines, to ensure all children have the chance to lead healthy lives.

Author: PATH

Publication date: 2014

Colonisation Endpoints in Streptococcus pneumoniae Vaccine Trials

This article, published in Vaccine, reviews recent developments in the area of using colonization as an endpoint for evaluating vaccine efficacy against Streptococcus pneumoniae. The authors also provide practical guidelines for estimation methods …

Author: Auranen K, Rinta-Kokko H, Goldblatt D, et al.

Publication date: 2013

Conjugate Vaccine Introduction in the African Meningitis Belt: Meeting Surveillance Objectives

This article, published in Tropical Medicine & International Health, asserts that surveillance systems and techniques for diagnosing bacterial meningitis and pneumococcal disease in the African meningitis belt have improved greatly over the …

Author: Mueller JE

Publication date: 2013

Conjugate Vaccines

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …

Author: Lockhart S

Publication date: 2003

The Contribution of Specific Pneumococcal Serogroups to Different Disease Manifestations: Implications for Conjugate Vaccine Formulation and Use, Part II

To assess whether certain serogroups of Streptococcus pneumoniae are preferentially associated with specific disease manifestations, we analyzed all recent pneumococcal disease studies and assessed the relative frequency of isolation of each …

Author: Hausdorff WP, Bryant J, Paradiso P, Siber G

Publication date: 2000

Coordinated Surveillance and Detection of Pneumococcal and Haemophilus influenzae type b (Hib) Disease in Developing Countries

This supplemental issue of Clinical Infectious Diseases provides numerous articles on the surveillance and detection of pneumococcal and Haemophilus influenzae type b disease in developing countries. Topics include progress and challenges in disease …

Author: Black S, Knoll MD, eds.

Publication date: 2009

A Cost Comparison of Introducing and Delivering Pneumococcal, Rotavirus and Human Papillomavirus Vaccines in Rwanda

This article, published in Vaccine, reports on a cost comparison of introducing multiple vaccines in a single country and then assessing the financial and economic impact at the time and implications for the future. The objective of the analysis was …

Author: Ngabo F, Levin A, Wang SA, et al.

Publication date: 2015

Current Concepts in Host-Microbe Interaction Leading to Pneumococcal Pneumonia

This article, published in Current Opinion in Infectious Diseases, reviews new insights into the pathogenesis of pneumococcal disease. The authors discuss new mechanisms by which microbial factors govern the ability of pneumococcus to progress from …

Author: Vernatter J, Pirofski L

Publication date: 2013

Decline in Invasive Pneumococcal Disease After the Introduction of Protein-Polysaccharide Conjugate Vaccine

Published in the New England Journal of Medicine, this study examined population-based data from the Active Bacterial Core Surveillance of the Centers for Disease Control and Prevention to evaluate changes in the burden of invasive disease, defined …

Author: Whitney C, Farley M, Hadler J, et al.

Publication date: 2003

Decline in Pneumonia Admissions After Routine Childhood Immunization with Pneumococcal Conjugate Vaccine in the USA: A Time-Series Analysis

Published in The Lancet, this article assesses the effect of routine infant immunization with seven-valent pneumococcal conjugate vaccine (PCV7) on rates of all-cause and pneumococcal pneumonia admissions. ABSTRACT ONLY. (Learn how users in …

Author: Grijalva CG, Nuorti JP, Arbogast PG, et al.

Publication date: 2007

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