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Region: Global

Total results with these characteristics: 934

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Decade of Vaccines Collaboration

This website provides information about the Decade of Vaccines (DoV) Collaboration, a time-limited consultation process which, as planned, dissolved at the end of 2012. The DoV Collaboration brought together diverse stakeholders to develop a Global …

Author: Decade of Vaccines Collaboration

Published: 2012

Decline in Invasive Pneumococcal Disease After the Introduction of Protein-Polysaccharide Conjugate Vaccine

Published in the New England Journal of Medicine, this study examined population-based data from the Active Bacterial Core Surveillance of the Centers for Disease Control and Prevention to evaluate changes in the burden of invasive disease, defined …

Author: Whitney C, Farley M, Hadler J, et al.

Published: 2003

Decline in Pneumonia Admissions After Routine Childhood Immunization with Pneumococcal Conjugate Vaccine in the USA: A Time-Series Analysis

Published in The Lancet, this article assesses the effect of routine infant immunization with seven-valent pneumococcal conjugate vaccine (PCV7) on rates of all-cause and pneumococcal pneumonia admissions. ABSTRACT ONLY. (Learn how users in …

Author: Grijalva CG, Nuorti JP, Arbogast PG, et al.

Published: 2007

DefeatDD.org

This website provides comprehensive resources on diarrheal disease treatment interventions, including low-osmolarity oral rehydration solution, zinc treatment, and rotavirus vaccines. Traditional interventions such as improved sanitation and …

Author: PATH

Delivering Cervical Cancer Prevention in the Developing World

This report highlights new partnerships and innovations in cervical cancer prevention and treatment. It also provides profiles of success in increasing access to HPV vaccines and treatment from around the world, with country spotlights on Mexico, …

Author: Women Deliver

Published: 2011

Designing Safe Syringe Disposal Systems for Immunization Services

This 30-page manual for program managers helps guide decision-making related to safe syringe disposal at the district level. A range of disposal methods and issues are covered, including practical advice on incineration (with details on two small …

Author: PATH

Published: 2003

Designing Vaccines for Developing-Country Populations: Ideal Attributes, Delivery Devices, and Presentation Formats

This article, published in Procedia in Vaccinology, discusses the importance of designing vaccines with traits that will minimize complications for immunization programs and increase the likelihood of successful adoption. The article also summarizes …

Author: Kristensen D, Zaffran M

Published: 2010

Desirable Attributes of Vaccines for Deployment in Low-Resource Settings

This article, published in the Journal of Pharmaceutical Sciences, discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including enhanced stability and efficient packaging, that can help to …

Author: Chen D, Zehrung D

Published: 2013

Developing a Vision for Immunization Supply Systems in 2020: Landscape Analysis Summaries

Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses …

Author: PATH, World Health Organization

Published: 2011

Developing New Vaccines Against Pneumonia and Other Pneumococcal Diseases

This fact sheet, issued by PATH, outlines PATH's pneumococcal vaccine project from a technical perspective, including an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of vaccines …

Author: PATH

Published: 2014

Development and Clinical Evaluation of Prevnar 13, a 13-Valent Pneumocococcal CRM197 Conjugate Vaccine

This article, published in the Annals of the New York Academy of Sciences, discusses the development, clinical evaluation, and postlicensure impact of the 13-valent pneumococcal CRM(197) protein conjugate vaccine, PCV13, (Prevnar 13®). ABSTRACT …

Author: Gruber WC, Scott DA, Emini EA

Published: 2012

Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant

This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …

Author: Holmgren J, Bourgeois L, Carlin N, et al.

Published: 2013

Development and Technology Transfer of Haemophilus influenzae type b Conjugate Vaccines for Developing Countries

This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …

Author: Beurret M, Hamidi A, Kreeftenberg H

Published: 2012

Development of a Fast-Dissolving Tablet Formulation of a Live Attenuated Enterotoxigenic E. coli Vaccine Candidate

A fast-dissolving tablet (FDT) that could be packaged in a compact stackable blister sheet is a potentially attractive option for formulating oral vaccines, since it would minimally impact the cold chain and could potentially be administered …

Author: Lal M, Priddy S, Bourgeois L, et al.

Published: 2013

Development of a Freeze-Stable Formulation for Vaccines Containing Aluminum Salt Adjuvants

This article, published in Vaccine, describes an approach to minimize reliance on the proper implementation of the cold chain to protect vaccines from freeze-thaw inactivation. By including PEG 300, propylene glycol, or glycerol in a hepatitis B …

Author: Jones Braun L, Tyagi A, Perkins S, et al.

Published: 2009

Development of a Humanized Monoclonal Antibody (MEDI-493) With Potent In Vitro and In Vivo Activity Against Respiratory Syncytial Virus

This article, published in The Journal of Infectious Diseases, details a preclinical study evaluating the ability of a humanized monoclonal antibody, MEDI-493 (later named palivizumab and marketed at Synagis®), to recognize a conserved …

Author: Johnson S, Oliver C, Prince GA, et al.

Published: 1997

Development of a Low-Dose Challenge Model for Evaluation of Vaccines for Enterotoxigenic E. coli (ETEC) in Volunteers

This presentation from the Vaccines for Enteric Diseases conference provides results from a clinical trial that found the human challenge model currently being used to test vaccines against enterotoxigenic Escherichia coli (ETEC) is utilizing a …

Author: Harro C, DeNearing B, Marcum A, et al.

Published: 2009

Development of Antibodies Against the Putative Proteinase Maturation Protein A in Relation to Pneumococcal Carriage and Otitis Media

Published in FEMS Immunology and Medical Microbiology, this article examines serum anti-pneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal …

Author: Bogaert D, Holmlund E, Lahdenkari M, et al.

Published: 2006

Development of Lactococcal GEM-Based Pneumococcal Vaccines

Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed …

Author: Audouy S, van Selm S, van Roosmalen M, et al.

Published: 2007

The Development of Live, Attenuated Rotavirus Vaccines: A Manufacturer's Resource Guide

This guide is a compilation of publicly available information about the manufacturing process of rotavirus vaccines, and aims to provide a resource for manufacturers interested in developing and registering an attenuated, oral rotavirus vaccine. …

Author: PATH, GAVI Alliance

Published: 2006

Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries

This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …

Author: Heidt PJ, Walker RI, Rusch V, eds.

Published: 2011

Development of Vaccines Against Meningococcal Disease

This article, published in the Lancet, reviews the currently available vaccines against meningococcal disease, as well as research and development efforts toward the development of additional vaccines against the disease. ABSTRACT …

Author: Jódar L, Feavers IM, Salisbury D, Granoff DM

Published: 2002

Diagnostic and Laboratory Testing Aspects of JE

This slide presentation give an overivew of the diagnostic and laboratory testing aspects of JE and can be apdated to fit your audience.

Author: PATH

Published: 2007

Diarrheal Disease: Solutions to Defeat a Global Killer

Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, …

Author: PATH

Published: 2009

Diarrhoea: Why Children Are Still Dying and What Can Be Done

This joint report from the World Health Organization and the United Nations Children's Fund (UNICEF) focuses attention on the prevention and management of diarrheal diseases. It examines the latest available information on the burden of childhood …

Author: World Health Organization, United Nations Children's Fund

Published: 2009

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