This book provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on vaccine-preventable diseases. In addition to chapters on more general vaccine-related topics, it …

This report examines the epidemiological evidence on the burden and distribution of pneumonia and assesses current levels of treatment and prevention. The report aims to raise awareness about this neglected disease and its causes, and serve as a …

Invasive meningococcal disease (IMD) is a serious public health threat, characterized by rapid symptom onset and high fatality rate, even after treatment. Efforts to prevent IMD remain challenging, because there is neither an immunogenic vaccine for …

This article, published in The British Medical Journal, describes a study of secondary meningococcal disease infection in which researchers used either meningococcal or tetanus toxoid vaccine to immunize household contacts of patients with …

To review how the research agenda for meningococcal disease in Africa has been changed by the advent of a serogroup A polysaccharide/tetanus toxoid protein conjugate vaccine and to define a new set of research priorities for study of meningococcal …

This article, published in Health Affairs, provides an overview of the Meningitis Vaccine Project as an example of how product development partnerships have reinvigorated research on vaccines for neglected diseases. The …

This article, published in Vaccine, emphasizes the importance of capsular polysaccharide vaccines for preventing disease caused by Neisseria meningitidis and Streptococcus pneumoniae in Africa, reiterating that these vaccines have been proven safe …

This article, published in the Pediatric Infectious Disease Journal, describes a study to investigate disabling sequelae among a cohort of children diagnosed with bacterial meningitis in urban Dakar, Senegal. Data from the study suggest …

This article, published in Clinical Microbiology Reviews, reviews the changing epidemiology of meningococcal disease in the United States, issues related to vaccine prevention, and recommendations on the use of the polysaccharide conjugate …

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global …

This article, published in The Pediatric Infectious Disease Journal, reviews routine vaccination with a single dose of conjugated meningococcal C vaccine at 14 months and a catch-up campaign, which has reduced the incidence of meningococcal C …

These pre-formatted PubMed searches will retrieve journal citations and available abstracts that address relevant issues related to meningococcus. Documents may be ordered through Loansome Doc if you have established an agreement with a …

This article, published in Expert Opinion on Biological Therapy, focuses on the development of meningococcal conjugate vaccines for serogroup A, with special emphasis on the needs of Africa. The author discusses the currently available conjugate …

This report summarizes a meeting organized by the World Health Organization to discuss meningococcal carriage studies in Africa that could provide data to support the introduction of the meningococcal A conjugate vaccine in the region. The …

This article, published in the journal Vaccine, reviews the status of research and development of vaccines against meningococcal disease due to Neisseria meningitidis as of 2006. The paper discusses the widespread vaccination with Group C conjugate …

This article, published in Vaccine, reviews the current status of research and development of vaccines against meningococcal disease due to Neisseria meningitidis. The authors discuss the successes of Group C meningitis vaccines in several European …

Lack of information on both the price and the different product characteristics of vaccines limits countries’ ability to operate affordable and effective immunization programs. This report aims to remedy some of the existing knowledge gaps by …

This article, published in The British Medical Journal, discusses a study examining biological and social risk factors for meningococcal disease in adolescents in six regions of England. The study finds that significant independent risk factors …

This article, featured in the World Health Organization's Weekly Epidemiological Record, presents what the potential scenarios were for meningitis epidemics in Africa in the 2007-2008 seasons and provides information on the expected availability of …

A meningococcal conjugate vaccine (MCV4) was introduced in the United States in 2005. Shortly after, case reports of Guillain-Barré syndrome (GBS), a serious demyelinating disease, began to be reported to the Vaccine Adverse Event Reporting …

This article, published in The Pediatric Infectious Disease Journal, reviews a study that administered three doses of a bivalent meningococcal A + C diphtheria-toxoid-conjugated vaccine (MenD), containing 1, 4, or 16 μg of each …

This article, published in the journal Vaccine, discusses a double-blind, randomized, controlled Phase 1 study in India to assess safety, immunogenicity, and antibody persistence of the new meningococcal group A conjugate vaccine (PsA-TT) …

The determinants of the disease dynamics of bacterial meningitis in the African meningitis belt are still poorly understood; nevertheless, it is often advocated that climate and mineral dust have a large impact. Several studies have investigated …

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews audiological and other long-term neurological sequelae in 157 cases and their controls 6 to 12 months after an epidemic of group A meningococcal …

This article, published in Infection and Immunity, reviews the serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom and applies the criteria to toddlers to evaluate immune response. The results indicate …