The authors of this article, which is a chapter in a monograph published in Vaccine, purport that as HPV vaccines come to market, they will face education and training challenges similar to those of other new vaccines, along with HPV-specific …

To prepare for the post-eradication period of polio and meet expected demand for inactivated polio vaccine (IPV), the production capacity of wild-type IPV needs to increase. However, the strains used for this process require stringent containment …

This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

This article, published in Human Vaccines, reports on a study that aimed to characterize the immediate qualitative changes of hepatitis B vaccine caused by freeze exposure. The vaccine was subjected to freezing temperatures ranging from 0°C to …

Highly sensitive and reliable assays based on the quantitation of immunologically relevant component(s) in recombinant or whole parasite-based vaccines would facilitate pre-clinical and clinical phases and the monitoring of malaria vaccine …

This attractive PowerPoint show is an immunization advocacy tool designed to be adapted for different situations. Presenters are encouraged to insert their organizational logo, add or subtract pages, substitute images, or revise the text, depending …

This fact sheet explains how the US Centers for Disease Control and Prevention develops their recommended childhood immunization schedule and provides answers to several frequently asked questions about the schedule. This document is intended for …

This report provides a comprehensive examination of the United States' childhood immunization schedule. The committee convened to prepare this report was tasked with identifying research approaches, methodologies, and study designs that could …

Information for parents and health care workers about diseases and vaccines, extensive questions and answers, and charts comparing disease risk versus vaccine risk.

COTS is an e-book, funded by the US Agency for International Development, designed to export the clinical, scientific, and public health expertise on cholera and shigellosis from the International Centre for Diarrhoeal Disease Research, …

Written by pediatrician and author Ari Brown, MD, this six-page handout addresses the concerns of vaccine-hesitant parents, including vaccine safety, autism, and alternative vaccination schedules.

This study, published in PLoS Medicine, provides a clear, quantitative demonstration of the connections that exist between major meningococcal meningitis (MCM) epidemics and regional climate variability in Africa. This statistically robust …

This article, published in the New England Journal of Medicine, offers a comprehensive review of virologic, epidemiologic, and clinical data on influenza A(H1N1) virus infections during the 2009 pandemic and summarizes key issues for clinicians …

This PowerPoint presentation trains doctors and health care workers in areas where Japanese encephalitis is endemic on how to assess a patient presenting with acute encephalitis syndrome. This version has still images only; a version with video …

After a multicenter study in several European countries, investigators determined that acute gastroenteritis caused by rotavirus resulted in more hospitalizations and emergency department visits than acute gastroenteritis from another cause. This …

This presentation provides an overview of the clinical manifestations and diagnosis of encephalitis. This presentation can be adapted for your specific use.

This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …

This article, published in Vaccine, describes the results of a randomized, comparator controlled, double-blind Phase 1 trial in 60 Swedish adults testing a prototype of a new oral vaccine candidate against enterotoxigenic Escherichia coli (ETEC) …

This fact sheet provides an overview of the development and testing of malaria vaccine candidates through clinical trials, including an explanation of why trials are important and descriptions of each clinical trial phase.

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …

This study, published in PLoS Medicine, aimed to determine how levels of colonization with different bacterial meingococcal serogroups change over time, and how the patterns of disease relate to such changes in the Kassena-Nankana District of …

This article, published in Médecine et Maladies Infectieuses, provides an overview of a cross-sectional, descriptive study to identify strains of Neisseria meningitidis isolated from 2005 to 2007 in Mali. Neisseria meningitidis appeared in 144 …

This issue brief is written for civil society leaders seeking to expand access to cervical cancer prevention and control resources in their communities. These resources include HPV vaccines for young adolescents and established and new screening and …

From the Bulletin of the World Health Organization, researchers evaluated the clinical case definition of acute encephalitis syndrome, which the standards use for identification of JE patients, to determine its sensitivity and specificity.

This fact sheet provides information on cold chain and logistics for vaccine delivery, including challenges for managing the cold chain, examples of effective cold chain management, and the costs associated with the cold chain.