Resource type: Peer-reviewed journal
Total results with these characteristics: 595
- Costs of Meningitis Sequelae in Children in Dakar, Senegal
In economic evaluations of vaccines protecting against meningitis, treatment and productivity costs due to meningitis sequelae are rarely included in studies from low-income countries, mainly due to lack of data. This study, published in The …
Author: Griffiths UK, Dieye Y, Fleming J, Hajjeh R, Edmond K
- Cotton Rats Previously Immunized With a Chimeric RSV FG Glycoprotein Develop Enhanced Pulmonary Pathology When Infected With RSV, a Phenomenon not Encountered Following Immunization With Vaccinia-RSV Recombinants or RSV
In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …
Author: Connors M, Collins PL, Firestone CY, et al.
- Critical Episodes in the Understanding and Control of Epidemic Meningococcal Meningitis
Epidemic meningococcal meningitis continues to be an important worldwide cause of morbidity and mortality, especially in developing countries. Throughout its history, a number of "critical episodes" have occurred that have enhanced understanding of …
Author: Artenstein AW, LaForce FM
- Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus
This article, published in The New England Journal of Medicine, describes a study to assess preexisting immunity in humans to the new pandemic influenza A(H1N1) virus in order to evaluate seasonal vaccine strategies. Researchers used a …
Author: Hancock K, Veguilla V, Lu X, et al.
- Current Concepts in Host-Microbe Interaction Leading to Pneumococcal Pneumonia
This article, published in Current Opinion in Infectious Diseases, reviews new insights into the pathogenesis of pneumococcal disease. The authors discuss new mechanisms by which microbial factors govern the ability of pneumococcus to progress from …
Author: Vernatter J, Pirofski L
- Current Knowledge Regarding the Investigational 13-valent Pneumococcal Conjugate Vaccine
This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …
Author: Dinleyici EC, Yargic ZA
- Current Use and Development of Vaccines for Japanese Encephalitis
This literature review, published in Expert Opinion on Biological Therapy, analyzes use of current JE vaccines and development of alternative vaccine candidates. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to …
Author: Beasley D, Lewthwaite P, Solomon T.
- A Decade of Japanese Encephalitis Surveillance in Sarawak, Malaysia: 1997-2006
From the journal Tropical Medicine and International Health, this summary of surveillance data from Malaysia reveals seasonal peak incidence, age distribution of JE cases, and effect of the JE immunization program on disease incidence.
Author: Wong SC, Ooi MH, Abdullah AR, et al.
- Decade of Vaccines
This supplement to Vaccine features articles on the Decade of Vaccines Global Vaccine Action Plan strategic objectives and the opportunities and challenges associated with its implementation. The 27 articles in the supplement cover a range of …
Author: Alonso PL, de Quadros CA, Lal AA, eds.
- Decline in Invasive Pneumococcal Disease After the Introduction of Protein-Polysaccharide Conjugate Vaccine
Published in the New England Journal of Medicine, this study examined population-based data from the Active Bacterial Core Surveillance of the Centers for Disease Control and Prevention to evaluate changes in the burden of invasive disease, defined …
Author: Whitney C, Farley M, Hadler J, et al.
- Decline in Pneumonia Admissions After Routine Childhood Immunization with Pneumococcal Conjugate Vaccine in the USA: A Time-Series Analysis
Published in The Lancet, this article assesses the effect of routine infant immunization with seven-valent pneumococcal conjugate vaccine (PCV7) on rates of all-cause and pneumococcal pneumonia admissions. ABSTRACT ONLY. (Learn how users in …
Author: Grijalva CG, Nuorti JP, Arbogast PG, et al.
- Definition and Characterization of Localised Meningitis Epidemics in Burkina Faso: A Longitudinal Retrospective Study
The epidemiology of meningococcal meningitis in the African meningitis belt is characterized by seasonality, localized epidemics, and epidemic waves. To facilitate research and surveillance, the authors of this article, published in BMC Infectious …
Author: Tall H, Hugonnet S, Donnen P, et al.
- Designing Vaccines for Developing-Country Populations: Ideal Attributes, Delivery Devices, and Presentation Formats
This article, published in Procedia in Vaccinology, discusses the importance of designing vaccines with traits that will minimize complications for immunization programs and increase the likelihood of successful adoption. The article also summarizes …
Author: Kristensen D, Zaffran M
- Desirable Attributes of Vaccines for Deployment in Low-Resource Settings
This article, published in the Journal of Pharmaceutical Sciences, discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including enhanced stability and efficient packaging, that can help to …
Author: Chen D, Zehrung D
- Development and Clinical Evaluation of Prevnar 13, a 13-Valent Pneumocococcal CRM197 Conjugate Vaccine
This article, published in the Annals of the New York Academy of Sciences, discusses the development, clinical evaluation, and postlicensure impact of the 13-valent pneumococcal CRM(197) protein conjugate vaccine, PCV13, (Prevnar 13®). ABSTRACT …
Author: Gruber WC, Scott DA, Emini EA
- Development and Implementation of a National Programme for the Management of Severe and Very Severe Pneumonia in Children in Malawi
This article, published in PLoS Medicine, provides an overview of the development and implementation of a national program for the management of severe and very severe childhood pneumonia in Malawi. Based on a successful delivery model used by the …
Author: Enarson PM, Gie R, Enarson DA, Mwansambo C
- Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant
This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …
Author: Holmgren J, Bourgeois L, Carlin N, et al.
- Development and Technology Transfer of Haemophilus influenzae type b Conjugate Vaccines for Developing Countries
This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …
Author: Beurret M, Hamidi A, Kreeftenberg H
- Development of a Fast-Dissolving Tablet Formulation of a Live Attenuated Enterotoxigenic E. coli Vaccine Candidate
A fast-dissolving tablet (FDT) that could be packaged in a compact stackable blister sheet is a potentially attractive option for formulating oral vaccines, since it would minimally impact the cold chain and could potentially be administered …
Author: Lal M, Priddy S, Bourgeois L, et al.
- Development of a Freeze-Stable Formulation for Vaccines Containing Aluminum Salt Adjuvants
This article, published in Vaccine, describes an approach to minimize reliance on the proper implementation of the cold chain to protect vaccines from freeze-thaw inactivation. By including PEG 300, propylene glycol, or glycerol in a hepatitis B …
Author: Jones Braun L, Tyagi A, Perkins S, et al.
- Development of a Group A Meningococcal Conjugate Vaccine, MenAfriVac™
Group A meningococcal disease has been an important public health problem in sub-Saharan Africa for over a century. From 2003 to 2009 a monovalent group A conjugate vaccine, MenAfriVac™, was developed through an innovative public/private …
Author: Frasch C, Preziosi M-P, LaForce FM
- Development of a Humanized Monoclonal Antibody (MEDI-493) With Potent In Vitro and In Vivo Activity Against Respiratory Syncytial Virus
This article, published in The Journal of Infectious Diseases, details a preclinical study evaluating the ability of a humanized monoclonal antibody, MEDI-493 (later named palivizumab and marketed at Synagis®), to recognize a conserved …
Author: Johnson S, Oliver C, Prince GA, et al.
- Development of Antibodies Against the Putative Proteinase Maturation Protein A in Relation to Pneumococcal Carriage and Otitis Media
Published in FEMS Immunology and Medical Microbiology, this article examines serum anti-pneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal …
Author: Bogaert D, Holmlund E, Lahdenkari M, et al.
- Development of Lactococcal GEM-Based Pneumococcal Vaccines
Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed …
Author: Audouy S, van Selm S, van Roosmalen M, et al.
- Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries
This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …
Author: Heidt PJ, Walker RI, Rusch V, eds.