Topic: Disease/vaccine specific information
Total results with these characteristics: 996
- Colonisation Endpoints in Streptococcus pneumoniae Vaccine Trials
This article, published in Vaccine, reviews recent developments in the area of using colonization as an endpoint for evaluating vaccine efficacy against Streptococcus pneumoniae. The authors also provide practical guidelines for estimation methods …
Author: Auranen K, Rinta-Kokko H, Goldblatt D, et al.
- A Combination Vaccine Consisting of Three Live Attenuated Enterotoxigenic Escherichia coli Strains Expressing a Range of Colonization Factors and LTB is Well Tolerated and Immunogenic in a Placebo-Controlled Double-Blind Phase 1 Trial in Healthy Adults
This article, published in Clinical and Vaccine Immunology, describes the results of a Phase 1 trial of a trivalent, live attenuated enterotoxigenic Escherichia coli vaccine candidate, ACE527. The study indicated that ACE527 had a strong safety …
Author: Harro C, Sack D, Bourgeois AL, et al.
- Common Virus and Senseless Killer: Briefing Paper on Rotavirus
This briefing paper underscores the burden of rotavirus disease and highlights the promise of vaccines to combat the virus as the global health community prepares for worldwide introduction.
- Communication for Polio Eradication and Routine Immunization: Checklists and Easy Reference Guides
This document provides a collection of checklists that serve as a quick-reference communications and social mobilization guide on aspects of routine immunization and disease surveillance, in addition to supplementary immunization for polio …
Author: World Health Organization, United Nations Children's Fund, US Agency for International Development
- Community Diarrhea Incidence Before and After Rotavirus Vaccine Introduction in Nicaragua
This article, published in the American Journal of Tropical Medicine and Hygiene, reports on a study that compared the incidence of diarrhea before and after the introduction of the pentavalent rotavirus vaccine in Leon, Nicaragua. The results …
Author: Becker-Dreps S, Meléndez M, Liu L, et al.
- Community Perceptions of Malaria and Vaccines in the South Coast and Busia Regions of Kenya
Malaria is a leading cause of morbidity and mortality in children younger than 5 years in Kenya. Within the context of planning for a vaccine to be used alongside existing malaria control methods, this study, published in Malaria …
Author: Ba-Nguz A, Bingham A, Collymore Y, et al.
- Community Perceptions of Malaria and Vaccines in Two Districts of Mozambique
Malaria is a leading cause of mortality and morbidity in Mozambique, with nearly three-quarters of the country’s malaria-related deaths occurring in children younger than five years. A malaria vaccine is not yet available, but planning is …
Author: Bingham A, Gaspar F, Lancaster K, Conjera J, Collymore Y, Ba-Nguz A
- Comparative Evaluation of the Potential Impact of Rotavirus Versus HPV Vaccination in GAVI-Eligible Countries: A Preliminary Analysis Focused on the Relative Disease Burden
This article, published in BMC Infectious Diseases, reports on a study that aimed to provide early insight into how the comparative impact of different new vaccines could be assessed in resource-poor settings with respect to affordability, …
Author: Kim SY, Sweet S, Chang J, Goldie SJ
- Comparative Review of Three Cost-Effectiveness Models for Rotavirus Vaccines in National Immunization Programs: A Generic Approach Applied to Various Regions in the World
This article, published in BMC Medicine, critically reviews available cost-effectiveness models for rotavirus vaccination, comparing their designs using a standardized approach and studying the similarities and differences in cost-effectiveness …
Author: Postma MJ, Jit M, Rozenbaum MH, Standaert BA, Tu HA, Hutubessy RCW
- Comparison of Cost-of-Illness with Willingness-to-Pay Estimates to Avoid Shigellosis: Evidence from China
Published in Health Policy and Planning, this compares cost-of-illness (COI) with stated preference estimates of willingness-to-pay associated with shigellosis in a rural area of China to evaluate the economic benefits of disease …
Author: Guh S, Xingbao C, Poulos C, et al.
- Comparison of the Immunogenicity and Safety of Measles Vaccine Administered Alone or With Live, Attenuated Japanese Encephalitis SA 14-14-2 Vaccine in Philippine Infants
This article, published in the journal Vaccine, presents data generated through a PATH-supported study that demonstrated safe and immunogenic coadministration of measles vaccine and the live, attenuated japanese …
Author: Gatchalian S, Yao Y, Zhoub B, et al.
- The Compelling Need for Game-Changing Influenza Vaccines: An Analysis of the Influenza Vaccine Enterprise and Recommendations for the Future
This report provides a review of all aspects of influenza vaccine research and development, financing, manufacturing, efficacy, safety, regulatory issues, procurement, distribution, usage, public education, consumer acceptance, and public policy. …
Author: Center for Infectious Disease Research & Policy
- A Comprehensive Approach to Rotavirus Vaccines
This fact sheet highlights PATH's work to address rotavirus and includes general information about its efforts to increase access to and effectiveness of existing vaccines, as well as to develop new vaccines.
- Comprehensive Cervical Cancer Prevention and Control: A Healthier Future for Girls and Women
This World Health Organization Guidance Note advocates for a comprehensive approach to cervical cancer prevention and control and is aimed at senior policy makers and programme managers. It describes the need to deliver effective interventions …
Author: World Health Organization
- Concomitant Administration of Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) and Measles, Mumps, Rubella (MMR) Vaccine: Randomized Study in Toddlers in Taiwan
This article, published in Vaccine, reports on a study that examined the safety and efficacy of administering Japanese encephalitis vaccine (JE-CV) and measles, mumps, rubella (MMR) vaccine six weeks apart or concomitantly in children aged 12 to 18 …
Author: Huang L-M, Lin T-Y, Chiu C-H, et al.
- Conducting Formative Research for HPV Vaccination Program Planning: Practical Experience from PATH
From 2006 to 2011, PATH conducted demonstration projects in four low- and middle-income countries—India, Peru, Uganda, and Vietnam—to provide evidence for decision-making about public-sector introduction of human papillomavirus (HPV) …
- Conducting Vaccine Clinical Trials in Sub-Saharan Africa: Operational Challenges and Lessons Learned From the Meningitis Vaccine Project
The Meningitis Vaccine Project (MVP) was established with the goal of developing, testing, licensing, and introducing an affordable group A meningococcal conjugate vaccine for Africa. The authors of this article, published in Vaccine, describe the …
Author: Marchetti E, Mazarin-Diop V, Chaumont J, et al.
- Confirmation of Japanese Encephalitis as an Endemic Human Disease Through Sentinel Surveillance in Indonesia
Japanese encephalitis (JE) results in significant mortality and disability in children in Asia. In Indonesia, despite recognition of JE virus transmission, reports of human disease have been few and from limited geographic areas. Hospital-based …
Author: Ompusunggu S, Hills S, Sembiring Maha M, et al.
- Conjugate Vaccine Introduction in the African Meningitis Belt: Meeting Surveillance Objectives
This article, published in Tropical Medicine & International Health, asserts that surveillance systems and techniques for diagnosing bacterial meningitis and pneumococcal disease in the African meningitis belt have improved greatly over the …
Author: Mueller JE
- Conjugate Vaccines
This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …
Author: Lockhart S
- Conjugate Vaccines and the Carriage of Haemophilus influenzae type b
Many junior doctors today have not had occasion to treat a child for Hib disease. The remarkable absence of cases of this disease is due to the use of conjugate vaccines. In countries with established Hib vaccination programs the incidence of …
Author: Barbour M
- The Contribution of Specific Pneumococcal Serogroups to Different Disease Manifestations: Implications for Conjugate Vaccine Formulation and Use, Part II
To assess whether certain serogroups of Streptococcus pneumoniae are preferentially associated with specific disease manifestations, we analyzed all recent pneumococcal disease studies and assessed the relative frequency of isolation of each …
Author: Hausdorff WP, Bryant J, Paradiso P, Siber G
- Control of Epidemic Meningococcal Disease. WHO Practical Guidelines. 2nd Edition
These guidelines, designed for physicians, laboratory workers, and health care administrators, provide comprehensive information on epidemiology and standard techniques for diagnosis, treatment, prevention, and control of meningococcal disease …
Author: World Health Organization
- Control of Japanese Encephalitis--Within Our Grasp?
The article, from the New England Journal of Medicine, provides an up-to-date summary of JE disease incidence, epidemiology, and vaccines against JE.
Author: Solomon T
- Coordinated Surveillance and Detection of Pneumococcal and Haemophilus influenzae type b (Hib) Disease in Developing Countries
This supplemental issue of Clinical Infectious Diseases provides numerous articles on the surveillance and detection of pneumococcal and Haemophilus influenzae type b disease in developing countries. Topics include progress and challenges in disease …
Author: Black S, Knoll MD, eds.