Browse resources

Topic: Vaccine safety and performance

Total results with these characteristics: 188

Passive Protection Against Respiratory Syncytial Virus Disease in Infants: the Role of Maternal Antibody

Respiratory syncytial virus (RSV) is responsible for serious respiratory disease in young infants. The authors of this article, published in The Pediatric Infectious Disease Journal, discuss the importance of maternal antibody in the immunity …

Author: Englund JA

Published: 1994

The Pink Book—Epidemiology and Prevention of Vaccine-Preventable Diseases

This book provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on vaccine-preventable diseases. In addition to chapters on more general vaccine-related topics, it …

Author: US Centers for Disease Control and Prevention

Published: 2012

Policy Reaction to Thimerosal in Vaccines

This study compares the differences in US and European responses to concerns about mercury exposure from thimerisol in vaccines.

Author: Child Health Evaluation and Research Unit, University of Michigan Medical Center & Duke University Medical Center

Published: 2001

Polio Vaccination

This web page provides information and resources for health professionals and the public about polio, vaccines against the disease, and eradication initiatives.

Author: US Centers for Disease Control and Prevention

Postmarketing Monitoring of Intussusception After RotaTeq Vaccination-United States, February 1, 2006 - February 15, 2007

This article, published in Morbidity and Mortality Weekly Report, summarizes the Advisory Committee on Immunization Practices review of post-marketing safety surveillance data on RotaTeq®, the rotavirus vaccine by Merck & Co., Inc. The …

Author: US Centers for Disease Control and Prevention

Published: 2007

Post-Marketing Surveillance of Rotavirus Vaccine Safety

This manual provides a review of current knowledge related to the safety of rotavirus vaccine and suggests approaches for monitoring safety after vaccine introduction in a country.

Author: World Health Organization

Published: 2009

Potential Intussusception Risk Versus Benefits of Rotavirus Vaccination in the United States

International data show a low-level increased risk of intussusception associated with rotavirus vaccination. This article, published in the Pediatric Infectious Disease Journal, reports on a study that compared potential vaccine-associated …

Author: Rishi D, Cortese M, Meltzer MI, et al.

Published: 2013

Prenatal Prevention of Respiratory Syncytial Virus Bronchiolitis

The authors of this article, published in Expert Review of Anti-infective Therapy, discuss how pregnancy may provide a unique window of opportunity for interventions aimed at preventing severe respiratory syncytial virus (RSV) infection in the …

Author: Belderbos M, Kimpen JLL, Bont L

Published: 2011

Press Briefing Transcripts: Media Availability on Vaccine Safety

This web page contains the transcript of a telebriefing between media and experts at the US Centers for Disease Control and Prevention on the science of vaccines and autism.

Author: US Centers for Disease Control and Prevention

Published: 2008

Prevention of Rotavirus Gastroenteritis in Infants and Children: Rotavirus Vaccine Safety, Efficacy, and Potential Impact of Vaccines

This article, published in Biologics: Targets & Therapy, provides a comprehensive review of current rotavirus vaccines, summarizing studies on their safety and efficacy, as well as special considerations that may inform future research studies. …

Author: Chandran A, Fitzwater S, Zhen A, Santosham M

Published: 2010

Principles and Considerations for Adding a Vaccine to a National Immunization Programme: From Decision to Implementation and Monitoring

This report reviews the principles and issues to be considered when making decisions about, planning, and implementing the introduction of a vaccine into a national immunization program. It also highlights ways to use the opportunity provided by the …

Author: World Health Organization

Published: 2014

Progress in Preventing Cervical Cancer: Updated Evidence on Vaccination and Screening

This issue of Outlook provides information on opportunities for preventing cervical cancer through vaccination and screening. It summarizes evidence on the safety and efficacy of human papillomavirus vaccines as well as successful approaches for …

Author: PATH

Published: 2010

Protecting Global Access to Lifesaving Vaccines: PATH’s Global Advocacy Strategy During the United Nations Environment Program Mercury Treaty Negotiations

This case study highlights PATH and its partners’ successful advocacy efforts to ensure the protection of vaccines containing thiomersal—a preservative used in multi-dose vaccines. In January 2013, government delegates finalized a global …

Author: PATH

Published: 2013

Protecting Public Trust in Immunization

This article, published in Pediatrics, discusses the issue of public trust in the safety and efficacy of vaccines and how it is one key to the success of immunization programs within the United States and globally. Allegations of harm from …

Author: Cooper LZ, Larson HJ, Katz SL

Published: 2008

Protecting the Herd: The Remarkable Effectiveness of the Bacterial Meningitis Polysaccharide-Protein Conjugate Vaccines in Altering Transmission Dynamics

The polysaccharide-protein conjugate vaccines against the pathogens responsible for bacterial meningitis have demonstrated remarkable effectiveness, far beyond the predicted individual efficacy. Approximately half of the effectiveness of these …

Author: Stephens DS

Published: 2011

Protective Association Between Rotavirus Vaccination and Childhood Seizures in the Year Following Vaccination in US Children

This article, published in Clinical Infectious Diseases, describes a review of data from 250,000 children born in the United States between March 2006—when rotavirus vaccines were introduced in the United States—and November 2009 for incidences …

Author: Payne DC, Baggs J, Zerr DM, et al.

Published: 2013

Questions and Answers on New Facts and Figures on Vaccines and the Global Mercury Treaty

This fact sheet provides frequently asked questions and answers regarding the use of thiomersal in vaccines and related issues surrounding vaccine safety. It includes information about the latest data available, the World Health Organization's …

Author: World Health Organization

Published: 2012

Reconstitution Technologies

This fact sheet provides an overview of single-dose, prefilled reconstitution devices (SPRDs), which can make reconstitution of critical vaccines safer and more economical. SPRDs can help eliminate adverse events or wastage that can occur with …

Author: PATH

Published: 2013

Respiratory Syncytial Virus Disease in Infants Despite Prior Administration of Antigenic Inactivated Vaccine

This article, published in the American Journal of Epidemiology, details studies conducted to determine the ability of a formalin inactivated vaccine candidate to protect against respiratory syncytial virus (RSV) disease. Results from the study …

Author: Kim HW, Canchola JG, Brandt CD, et al.

Published: 1969

Respiratory Virus Immunization: A Field Trial of Two Inactivated Respiratory Virus Vaccines; an Aqueous Trivalent Parainfluenza Virus Vaccine and an Alum-Precipitated Respiratory Syncytial Virus Vaccine

This article, published in the American Journal of Epidemiology, describes a field trial conducted to evaluate an inactivated, alum-precipitated respiratory syncytial virus (RSV) vaccine and an aqueous trivalent parainfluenza virus vaccine. Study …

Author: Fulginiti VA, Eller JJ, Sieber OF, Joyner JW, Minamitani M, Meiklejohn G

Published: 1969

Response to a Monovalent Influenza A (H1N1) 2009 Vaccine

This article, published in The New England Journal of Medicine, describes the methods, results, and conclusions from a randomized observer-blind, parallel-group trial evaluating two doses of an inactivated, split-virus 2009 influenza A(H1N1) vaccine …

Author: Greenberg ME, Lai MH, Hartel GF, et al.

Published: 2009

Revised Procedure for WHO Prequalification of Vaccines

This web page provides an explanation and link to the revised procedure for assessing the acceptability of vaccines in order to verify that they meet the specifications of the relevant United Nations agency for procurement and that they are produced …

Author: World Health Organization

Published: 2013

Risk of Intussusception after Monovalent Rotavirus Vaccination

This article, published in the New England Journal of Medicine, reports on a study that examined the risk of intussusception after monovalent rotavirus vaccination in a population in the United States. In this prospective postlicensure study of more …

Author: Weintraub ES, Baggs J, Duffy J, et al.

Published: 2014

Risk of Intussusception Following Administration of a Pentavalent Rotavirus Vaccine in US Infants

This article, published in the Journal of the American Medical Association, reports on a study that examined the rates of intussusception in  infants in the United States during the 1- to 7-day and 1- to 30-day windows following vaccination …

Author: Shui IM, Baggs J, Patel M, et al.

Published: 2012

The Road to Safe and Effective Vaccines

This fact sheet highlights the development of new vaccines through clinical trials and their role in providing safe and effective vaccines.

Author: PATH

Published: 2013