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Topic: Vaccine safety

Total results with these characteristics: 138

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Safety and Efficacy of an Attenuated Vaccine Against Severe Rotavirus Gastroenteritis

This study, published in the New England Journal of Medicine, evaluated the safety and efficacy of GSK’s rotavirus vaccine (Rotarix®), with a focus on determining risk of intussusception.

Author: Ruiz-Palacios G, Pérez-Schael I, Velázquez F, et al.

Published: 2006

Safety and Immunogenicity of a Novel Influenza Subunit Vaccine Produced in Mammalian Cell Culture

This article, published in the Journal of Infectious Diseases, describes a novel cell culture-derived influenza vaccine (CCIV) produced in Madin-Darby canine kidney cells. The Phase 3, multicenter study in Poland observed that CCIV was well …

Author: Szymczakiewicz-Multanowska A, Groth N, Bugarini R, et al.

Published: 2009

Safety and Immunogenicity of Concomitant Vaccination With the Cell-Culture Based Japanese Encephalitis Vaccine IC51 and the Hepatitis A Vaccine HAVRIX1440 in Healthy Subjects: A Single-Blind, Randomized, Controlled Phase 3 Study

In travelers often several pre-departure immunizations are indicated, thus data are needed about possible interactions between vaccines. This Phase 3 study investigated the immunogenicity and safety of IC51 (JE vaccine) and HAVRIX1440 (hepatitis A …

Author: Kaltenböck A, Dubischar-Kastner K, Eder G, et al.

Published: 2009

Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

This study, published in the New England Journal of Medicine, assessed the feasibility of integrating the RTS,S/AS02D malaria vaccine into a standard expanded program on immunization (EPI) schedule for infants. The study, conducted in …

Author: Abdulla S, Oberholzer R, Juma O, et al.

Published: 2008

Safety and Immunogenicity of Three Doses of a Neisseria Meningitidis A + C Diphtheria Conjugate Vaccine in Infants From Niger

This article, published in The Pediatric Infectious Disease Journal, reviews a study that administered three doses of a bivalent meningococcal A + C diphtheria-toxoid-conjugated vaccine (MenD), containing 1, 4, or 16 μg of each …

Author: Campagne G, Garba A, Fabre P, et al.

Published: 2000

Safety, Immunogenicity, and Antibody Persistence of a New Meningococcal Group A Conjugate Vaccine in Healthy Indian Adults

This article, published in the journal Vaccine, discusses a double-blind, randomized, controlled Phase 1 study in India to assess safety, immunogenicity, and antibody persistence of the new meningococcal group A conjugate vaccine (PsA-TT) …

Author: Kshirsagar N, Mur N, Thatte U, et al.

Published: 2007

Safety of Immunization Injections in Africa: Not Simply a Problem of Logistics

From the Bulletin of the World Health Organization, this report is an evaluation of a "logistic approach" on immunization injection safety. The investigators found that unsafe injection practices were generally due to a failure to …

Author: Dicko M, Oni AQ, Ganivet S, et al.

Published: 2000

Safety of the RTS,S/AS02A Malaria Vaccine in Mozambican Children During a Phase IIb Trial

This study, published in the journal Vaccine, evaluated the safety of the RTS,S/AS02A malaria vaccine in a proof of concept Phase IIb trial in Mozambican children aged one to four years. Overall, the study results indicate that the …

Author: Sacarlal J, Aponte JJ, Aide P, et al.

Published: 2008

The Science of Immunisation: Questions and Answers

This publication aims to address confusion created by contradictory information in the public domain regarding immunization. It sets out to explain the current situation in immunization science, including where there is consensus in the scientific …

Author: Australian Academy of Science

Published: 2012

Setting the Immunization Agenda Through Advocacy and Communication

This document reports on a high-level meeting about setting the immunization agenda through advocacy and communication, held in London in January 2008. The meeting was held jointly by the United Kingdom Department of Health and the World …

Author: World Health Organization

Published: 2008

Single Dose of SA 14-14-2 Vaccine Provides Long-term Protection Against Japanese Encephalitis: A Case-control Study in Nepalese Children 5 Years After Immunization

Published in the journal Vaccine, this article discusses the return of investigators to Nepali villages where they conducted a case control study that revealed 99 percent efficacy after one year among children who received a single dose of the …

Author: Tandan J, Ohrr H, Sohn Y, et al.

Published: 2007

State of the World's Vaccines and Immunization, Third Edition

This report focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals. It looks at the development and use of vaccines and the …

Author: World Health Organization, United Nations Children's Fund, World Bank

Published: 2009

Statement Regarding Rotarix and RotaTeq Rotavirus Vaccines and Intussusception

This statement summarizes several post-licensure evaluations on rotavirus vaccines and intussusception that were presented to the US Advisory Committee on Immunization Practices. Some studies performed outside the United States have detected a …

Author: US Centers for Disease Control and Prevention

Published: 2010

Strategic Advisory Group of Experts Recommendations: Rotavirus Vaccination

This issue of the Weekly Epidemiological Record reports on the World Health Organization's Strategic Advisory Group of Experts' recommendation for inclusion of rotavirus vaccines in all national immunization programs. The new …

Author: World Health Organization

Published: 2009

Subunit Influenza Vaccines Produced From Cell Culture or in Embryonated Chicken Eggs: Comparison of Safety, Reactogenicity, and Immunogenicity

This study, published in the Journal of Infectious Diseases, assessed the safety, reactogenicity, and immunogenicity of an injectable cell culture-derived influenza vaccine, compared with those of an injectable egg-based trivalent inactivated …

Author: Reisinger KS, Block SL, Izu A, Groth N, Holmes SJ

Published: 2009

Talking About Vaccines: Vaccine Safety

This web page contains links a number of vaccine safety resources, including websites, journal articles, and fact sheets.

Author: Immunization Action Coalition

Thimerosal

This web page provides a US Centers for Disease Control and Prevention (CDC) statement on the safety of thimerosal in vaccines and links to CDC and outside resources that provide further information on this topic. 

Author: US Centers for Disease Control and Prevention

Thimerosal in Vaccines

This page contains information on thimerosal, a mercury-containing preservative that has been used in vaccines. The page also includes links to other resources on thimerosal and vaccines.

Author: US Food and Drug Administration

Thimerosal in Vaccines: Questions and Answers

This World Health Organization link provides answers to 20 common questions about thimerosal.

Author: World Health Organization

Published: 2006

Thiomersal

This information sheet covers issue relating to the use of thiomersal (also known as thimerosal) in vaccines, including why it is used, evidence regarding safety, and the World Health Organization's position on the issue.

Author: World Health Organization

Published: 2011

Thiomersal - Questions and Answers

This in-depth fact sheet provides common questions and answers related to the use of thiomersal (also known as thimerosal) in vaccines. It includes general information about thiomersal, which vaccines contain it and why, updates on additional …

Author: World Health Organization

Published: 2011

Trends in Intussusception Hospitalizations Among US Infants Before and After Implementation of the Rotavirus Vaccination Program, 2000-2009

This article, published in the Journal of Infectious Diseases, reports on surveillance conducted following rotavirus vaccine introduction in 2006 that noted a small increase in intussusception among US infants aged 8 to 11 weeks, who would have …

Author: Yen C, Tate JE, Steiner CA, Cortese MM, Patel MM, Parashar UD

Published: 2012

Understanding Thimerosal, Mercury, and Vaccine Safety

This fact sheet explains what thimerosal is and why it is used as a preservative in some multi-dose vials of influenza vaccine, and highlights conclusions from studies examining thimerosal safety in vaccines.

Author: US Centers for Disease Control and Prevention

Published: 2012

The Vaccine Confidence Project

This project was formed to build a multi-disciplinary network of biomedical scientists, decision scientists, psychologists, and social scientists to examine the influences and decision-making processes as individuals around the world, including …

Author: London School of Hygiene & Tropical Medicine

Vaccine Discovery and Translation of New Vaccine Technology

An unprecedented increase in new vaccine development has occurred over the past three decades. This article, published in The Lancet, discusses new methods of discovery, such as reverse vaccinology, structural biology, and systems biology, which …

Author: Rappuoli R, Black S, Lambert PH

Published: 2011

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