Browse resources

Topic: Vaccine safety and performance

Total results with these characteristics: 214

Maternal Immunization: US FDA Regulatory Considerations

Vaccination of pregnant women provides important health benefits to both mother and infant, and has been an important disease-prevention strategy in these two groups. However, since pregnant women are usually excluded from participation in clinical …

Author: Gruber MF

Published: 2003

Meeting of the Global Advisory Committee on Vaccine Safety, December 2010: Rotavirus Vaccine and Intussusception

This article, from the Weekly Epidemiological Record, reports on the outcome of a meeting of the World Health Organization's independent, authoritative vaccine safety committee where they reviewed postmarketing surveillance that indicated the …

Author: World Health Organization

Published: 2011

Meningococcal Vaccines: Current Issues and Future Strategies

The authors of this article, published in Drugs, provide an overview of the history and current state of meningococcal vaccines. They also review issues related to the vaccines that still need to be addressed including duration of protection, …

Author: Cohn AC, Harrison LH

Published: 2013

Meningococcal Vaccines: What You Need to Know

This fact sheet provides information on meningococcal vaccines, including who should get the vaccine, vaccine-associated risks, and where you can learn more about meningococcal disease and vaccines.

Author: US Centers for Disease Control and Prevention

Published: 2008

Mercury Levels in Newborns and Infants After Receipt of Thimerosal-Containing Vaccines

This article, published in Pediatrics, reports on a study assessing blood levels and the elimination of ethyl mercury after vaccination of infants with thimerosal-containing vaccines. The authors concluded that the blood half-life of intramuscular …

Author: Pichichero ME, Gentile A, Giglio N, et al.

Published: 2008

Monitoring Adverse Events Following Immunization With a New Conjugate Vaccine Against Group A Meningococcus in Niger, September 2010

In Niger, the introduction campaign of MenAfriVac™, a new conjugate vaccine against Neisseria meningitidis serogroup A, was conducted in the District of Filingue, during September 2010. The authors of this article, published in …

Author: Chaibou MS, Bako H, Salisou L, et al.

Published: 2012

A Multi-Center, Qualitative Assessment of Pediatrician and Maternal Perspectives on Rotavirus Vaccines and the Detection of Porcine circovirus

This article, published in BMC Pediatrics, reports on research that evaluated perceptions among physicians and mothers after the 2011 finding of DNA fragments of Porcine circovirus in rotavirus vaccines. Physicians expressed that the finding was of …

Author: Payne DC, Humiston S, Opel D, et al.

Published: 2011

Neuropsychological Performance 10 Years After Immunization in Infancy With Thimerosal-Containing Vaccines

This study, published in the journal Pediatrics, compares the neuropsychological performance, ten years after vaccination, of two groups of children exposed randomly to different amounts of thimerosal through immunization. The study concludes that, …

Author: Tozzi AE, Bisiacchi P, Tarantino V, et al.

Published: 2009

New Decade of Vaccines

In December 2010, global health leaders committed to making the next 10 years the Decade of Vaccines - to ensure discovery, development, and delivery of lifesaving vaccines globally, especially to the poorest countries. This special series of …

Author: Horton R, ed.

Published: 2011

The Next Decade of Vaccines: Societal and Scientific Challenges

This article, published in The Lancet, aims to provide a deeper understanding of the societal factors that threaten to compromise realization of the public health gains that immunization can achieve in the next decade and beyond. Also discussed are …

Author: Moxon ER, Siegrist CA

Published: 2011

No Vaccine for the Scaremongers

Published in the Bulletin of the World Health Organization, this article discusses anxieties over safety of vaccines and the damage these worries could have on immunization programs.

Author: World Health Organization

Published: 2008

A Novel Influenza A (H1N1) Vaccine in Various Age Groups

This article, published in The New England Journal of Medicine, details a randomized clinical trial conducted in China to evaluate the safety and immunogenicity of a split-virus, inactivated vaccine candidate against the 2009 pandemic …

Author: Zhu F, Wang H, Fang H, et al.

Published: 2009

On-Time Vaccine Receipt in the First Year Does Not Adversely Affect Neuropsychological Outcomes

This article, published in the journal Pediatrics, examines whether children who received recommended vaccines on time during the first year of life had different neuropsychological outcomes at 7 to 10 years of age as compared with children with …

Author: Smith MJ, Woods CR

Published: 2010

Optimum Dosing of Pneumococcal Conjugate Vaccine For Infants: A Landscape Analysis of Evidence Supporting Different Schedules

This supplement of the Pediatric Infectious Disease Journal features nine articles on the considerations for pneumococcal conjugate vaccine (PCV) dosing schedules. This systematic literature review and corresponding analyses support the dosing …

Author: O’Brien KL, Goldblatt D, Whitney CG, eds.

Published: 2014

Passive Protection Against Respiratory Syncytial Virus Disease in Infants: the Role of Maternal Antibody

Respiratory syncytial virus (RSV) is responsible for serious respiratory disease in young infants. The authors of this article, published in The Pediatric Infectious Disease Journal, discuss the importance of maternal antibody in the immunity …

Author: Englund JA

Published: 1994

The Pink Book—Epidemiology and Prevention of Vaccine-Preventable Diseases

This book provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on vaccine-preventable diseases. In addition to chapters on more general vaccine-related topics, it …

Author: US Centers for Disease Control and Prevention

Published: 2012

Policy Reaction to Thimerosal in Vaccines

This study compares the differences in US and European responses to concerns about mercury exposure from thimerisol in vaccines.

Author: Child Health Evaluation and Research Unit, University of Michigan Medical Center & Duke University Medical Center

Published: 2001

Polio Vaccination

This web page provides information and resources for health professionals and the public about polio, vaccines against the disease, and eradication initiatives.

Author: US Centers for Disease Control and Prevention

Postmarketing Monitoring of Intussusception After RotaTeq Vaccination-United States, February 1, 2006 - February 15, 2007

This article, published in Morbidity and Mortality Weekly Report, summarizes the Advisory Committee on Immunization Practices review of post-marketing safety surveillance data on RotaTeq®, the rotavirus vaccine by Merck & Co., Inc. The …

Author: US Centers for Disease Control and Prevention

Published: 2007

Post-Marketing Surveillance of Rotavirus Vaccine Safety

This manual provides a review of current knowledge related to the safety of rotavirus vaccine and suggests approaches for monitoring safety after vaccine introduction in a country.

Author: World Health Organization

Published: 2009

Potential Intussusception Risk Versus Benefits of Rotavirus Vaccination in the United States

International data show a low-level increased risk of intussusception associated with rotavirus vaccination. This article, published in the Pediatric Infectious Disease Journal, reports on a study that compared potential vaccine-associated …

Author: Rishi D, Cortese M, Meltzer MI, et al.

Published: 2013

Prenatal Prevention of Respiratory Syncytial Virus Bronchiolitis

The authors of this article, published in Expert Review of Anti-infective Therapy, discuss how pregnancy may provide a unique window of opportunity for interventions aimed at preventing severe respiratory syncytial virus (RSV) infection in the …

Author: Belderbos M, Kimpen JLL, Bont L

Published: 2011

Press Briefing Transcripts: Media Availability on Vaccine Safety

This web page contains the transcript of a telebriefing between media and experts at the US Centers for Disease Control and Prevention on the science of vaccines and autism.

Author: US Centers for Disease Control and Prevention

Published: 2008

Prevention of Rotavirus Gastroenteritis in Infants and Children: Rotavirus Vaccine Safety, Efficacy, and Potential Impact of Vaccines

This article, published in Biologics: Targets & Therapy, provides a comprehensive review of current rotavirus vaccines, summarizing studies on their safety and efficacy, as well as special considerations that may inform future research studies. …

Author: Chandran A, Fitzwater S, Zhen A, Santosham M

Published: 2010

Principles and Considerations for Adding a Vaccine to a National Immunization Programme: From Decision to Implementation and Monitoring

This report reviews the principles and issues to be considered when making decisions about, planning, and implementing the introduction of a vaccine into a national immunization program. It also highlights ways to use the opportunity provided by the …

Author: World Health Organization

Published: 2014