This site contains links to select programs, data, and materials, from various development organizations focused on immunization initiatives, including avian influenza and polio.

This article, published in BMC Medicine, critically reviews available cost-effectiveness models for rotavirus vaccination, comparing their designs using a standardized approach and studying the similarities and differences in cost-effectiveness …

This report provides a review of all aspects of influenza vaccine research and development, financing, manufacturing, efficacy, safety, regulatory issues, procurement, distribution, usage, public education, consumer acceptance, and public policy. …

This fact sheet highlights PATH's work to address rotavirus and includes general information about its efforts to increase access to and effectiveness of existing vaccines, as well as to develop new vaccines.

This WHO Guidance Note advocates for a comprehensive approach to cervical cancer prevention and control and is aimed at senior policy makers and programme managers. It describes the need to deliver effective interventions across the female life …

From 2006 to 2011, PATH conducted demonstration projects in four low- and middle-income countries—India, Peru, Uganda, and Vietnam—to provide evidence for decision-making about public-sector introduction of human papillomavirus (HPV) …

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …

Many junior doctors today have not had occasion to treat a child for Hib disease. The remarkable absence of cases of this disease is due to the use of conjugate vaccines. In countries with established Hib vaccination programs the incidence of …

To assess whether certain serogroups of Streptococcus pneumoniae are preferentially associated with specific disease manifestations, we analyzed all recent pneumococcal disease studies and assessed the relative frequency of isolation of each …

These guidelines, designed for physicians, laboratory workers, and health care administrators, provide comprehensive information on epidemiology and standard techniques for diagnosis, treatment, prevention, and control of meningococcal disease …

The article, from the New England Journal of Medicine, provides an up-to-date summary of JE disease incidence, epidemiology, and vaccines against JE.

This supplemental issue of Clinical Infectious Diseases provides numerous articles on the surveillance and detection of pneumococcal and Haemophilus influenzae type b disease in developing countries. Topics include progress and challenges in disease …

This fact sheet makes the case for why vaccines are a critical, cost-effective investment for improving global health and saving children's lives.

This article, published in the journal Vaccine, reviews potential correlates of protection against influenza and discusses some of the vaccination strategies that could result in optimal protection against epidemic and pandemic influenza. ABSTRACT …

This report from the WHO's Weekly Epidemiologic Record summarizes a meeting convened by PATH, WHO, and the US Centers for Disease Control and Prevention (CDC) on the economic burden of rotavirus disease and cost-effectiveness of vaccines. The …

This paper summarizes the results of a WHO/UNICEF study on the potential impact of immunization over the next decade and the financing required for immunization activities in the 72 poorest countries of the world.

This review, published in Vaccine, documents the available evidence showing that vaccination in low- and middle-income countries brings important economic benefits. The cost-effectiveness studies reviewed suggest to policy makers that vaccines are …

In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …

This paper examines the health risks posed by unsafe injections in Africa and outlines some of the programs that are helping reduce these risks.

This issue brief discusses how ensuring swift and efficient HPV vaccine introduction in developing countries will not only help address the burden of cervical cancer, but will also provide a valuable opportunity for AIDS vaccine researchers and …

This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …

This literature review, published in Expert Opinion on Biological Therapy, analyzes use of current JE vaccines and development of alternative vaccine candidates.

This website provides information about the DoV Collaboration which was launched in 2010 to enhance coordination across the global community by bringing together diverse stakeholders to develop an evidence-based, country-led global vaccine action …

Published in the New England Journal of Medicine, this study examined population-based data from the Active Bacterial Core Surveillance of the Centers for Disease Control and Prevention to evaluate changes in the burden of invasive disease, defined …

Published in The Lancet, this article assesses the effect of routine infant immunization with seven-valent pneumococcal conjugate vaccine (PCV7) on rates of all-cause and pneumococcal pneumonia admissions. ABSTRACT ONLY. (Learn how users in …