Many junior doctors today have not had occasion to treat a child for Hib disease. The remarkable absence of cases of this disease is due to the use of conjugate vaccines. In countries with established Hib vaccination programs the incidence of …

This study, published in the journal Archives of General Psychiatry, evaluates the rates of autism in California following the discontinued use of thimerosal in childhood vaccines. ABSTRACT ONLY. (Learn how users in developing countries …

To assess whether certain serogroups of Streptococcus pneumoniae are preferentially associated with specific disease manifestations, we analyzed all recent pneumococcal disease studies and assessed the relative frequency of isolation of each …

The article, from the New England Journal of Medicine, provides an up-to-date summary of JE disease incidence, epidemiology, and vaccines against JE.

This supplemental issue of Clinical Infectious Diseases provides numerous articles on the surveillance and detection of pneumococcal and Haemophilus influenzae type b disease in developing countries. Topics include progress and challenges in disease …

This article, published in the journal Vaccine, reviews potential correlates of protection against influenza and discusses some of the vaccination strategies that could result in optimal protection against epidemic and pandemic influenza. ABSTRACT …

Published in the Bulletin of the World Health Organization, this paper offers the first attempt to quantitatively evaluate the supportive supervision framework in Andhra Pradesh, India.

The authors of this article, published in PLoS ONE, applied cost-effectiveness modeling and a cold-chain impact assessment to aid decision-making on rotavirus vaccine introduction in Kenya. They conclude that use of either vaccine is cost-effective, …

This article, published in Value in Health, discusses a study to develop a cost function model to estimate the public treatment cost of shigellosis patients in Thailand. The study was an incidence-based cost-of-illness …

Published in the Journal of Pharmaceutical Finance, Economics & Policy, this article evaluates the potential use of vaccines against Japanese encephalitis (JE) and estimates the cost-effectiveness of mass vaccination campaigns and routine …

This review, published in Vaccine, documents the available evidence showing that vaccination in low- and middle-income countries brings important economic benefits. The cost-effectiveness studies reviewed suggest to policy makers that vaccines are …

This study, published in the journal Pediatrics, examines the costs and benefits of routine rotavirus vaccination for infants in the US, using a hypothetical cohort of unvaccinated infants. Researchers determined that, at current prices, …

This paper, published in the journal Vaccine, investigates whether routine infant immunization with either currently licensed rotavirus vaccine could be cost-effective in Taiwan. The authors modeled specific disease outcomes …

This article, published in the journal Pediatrics, discusses a study to evaluate and compare the projected health and economic impact of meningococcal conjugate A/C/Y/W-135 (MCV-4) vaccination of adolescents, toddlers, and infants in the United …

This study, published in BMC Infectious Diseases, developed a model to compare the cost and disease burden of rotavirus in unvaccinated children in Mexico. The study determined that it would be highly cost-effective to include rotavirus vaccine …

This article, published in Vaccine, evaluates the cost-effectiveness of introducing infant rotavirus vaccination in Armenia in 2012 using Rotarix(R)® using a multiple birth cohort model. The model considered the cost and health implications of …

From the Bulletin of the World Health Organization, this article investigates the cost-effectiveness of JE immunization in China and demonstrates that a JE immunization program can be a cost-saving intervention for countries.

Epidemic meningococcal meningitis remains a serious health threat in the African meningitis belt. New meningococcal conjugate vaccines are relatively costly and their efficiency will depend on cost savings realized from no longer having to respond …

This article, published in Clinical Infectious Diseases, discusses an anthropologic and economic study in Burkina Faso to understand perceptions and behavior relative to meningitis and to determine the cost of illness from bacterial …

Investigators found that rotavirus gastroenteritis incurs considerable use of health care resources and results in substantial costs for families of patients and employers. Routine rotavirus vaccination could significantly reduce the related …

In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …

Epidemic meningococcal meningitis continues to be an important worldwide cause of morbidity and mortality, especially in developing countries. Throughout its history, a number of "critical episodes" have occurred that have enhanced understanding of …

This article, published in The New England Journal of Medicine, describes a study to assess preexisting immunity in humans to the new pandemic influenza A(H1N1) virus in order to evaluate seasonal vaccine strategies. Researchers used a …

This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …

This literature review, published in Expert Opinion on Biological Therapy, analyzes use of current JE vaccines and development of alternative vaccine candidates.