This worksheet can be used during trainings to help health workers learn how to read time-temperature indicators on the Uniject® device, which is an autodisable, prefilled, single-use syringe that can be used with vaccines.

Project Optimize aims to provide national immunization programs with recommendations to build integrated health supply systems, including strategic linkages with the parastatal and private sector. This fact sheet describes the benefits of and …

This report details the US Centers for Disease Control and Prevention’s (CDC’s) Vaccine Management Business Improvement Project, which was an end-to-end reengineering of the US public-sector vaccine supply chain—from vaccine …

From the Bulletin of the World Health Organization, this report is an evaluation of a "logistic approach" on immunization injection safety. The investigators found that unsafe injection practices were generally due to a failure to …

SnapShots was an electronic publication of the IMMUNIZATIONbasics project (which ran from 2004 to 2009) and was designed to provide busy public health professionals with references and periodic updates from the immunization world. Although the …

This fact sheet discusses PATH's work on the development and implementation of technologies, such as vaccines and vaccine delivery devices, to improve the health of women and children in poor and remote areas around the world.

This issue of Health Affairs covers a variety of strategies for the "Decade of Vaccines." The articles included in the issue cover topics such as the business and economic benefits of vaccines, the moral case for vaccination, the …

This document reports on results from the Streamlining Immunization Logistics project, implemented between April 2005 and March 2006 in eight districts of Central Java and Yogyakarta, Indonesia. The project successfully demonstrated qualitative …

This report details the first UNICEF-hosted meeting of partners involved in immunization to enhance and coordinate the collective support provided to national governments for strengthening cold chain and logistics sytems.

This fact sheet describes work that Project Optimize is doing to enable immunization programs to take advantage of the true stability of vaccines by labeling them for use at ambient temperatures in a controlled temperature chain for limited periods …

This website, dedicated to strengthening immunization services, is managed by the World Health Organization-initiated TechNet Forum. The site provides an up-to-date news feature, a dictionary of immunization terms, articles …

This fact sheet describes a collaboration between the Albanian Ministry of Health and Project Optimize to install a short message service–based system that monitors and logs temperature conditions in peripheral cold chain equipment. The team …

Both Iran and Sudan utilize an alarm-based temperature recording system to monitor the performance of their national immunization cold stores. To better the utility and application of such systems in other countries, this report documents the …

This document addresses issues regarding potential exposure of temperature-sensitive vaccines to freezing temperatures and provides updated information on vaccine vial monitors, as well as a discussion of future advances in cold chain technology.

This article, published in Pediatrics, describes the importance of following recommendations for vaccine storage and outlines specific steps immunization providers should take to prevent storage of vaccines outside of their required temperatures.

This 66-page manual aims to help mid-level managers determine how much vaccine and safe-injection equipment they need to run their immunization program, how to manage its storage, distribution, and replacement, how to monitor the system, and how to …

Keeping heat-sensitive vaccines at the right temperature is crucial yet often difficult in areas with limited or no electrical power. Project Optimize collaborated with the Vietnam National Expanded Programme on Immunization to evaluate two …

This review compiles the literature available on the use of vaccines outside of the cold chain. Most of the studies analyzed in this review focus on hepatitis B, except one that examines meningococcal Group C vaccine. Most showed that there are …

Emphasis has long been placed on keeping vaccines cold, with less attention devoted to prevention of vaccine damage from freezing. Published reports and field evidence now demonstrate that freezing of vaccines in the cold chain is commonplace, …

This section of the World Health Organization website focuses on vaccine management issues including the cold chain, transport, stock management, and reconstitution of vaccines.

This issue of Global Health Magazine is focused on the topic of vaccines and immunization, and contains several expert-authored articles about different aspects of vaccine development and use worldwide. The issue includes an article co-authored by …

Project Optimize assessed the cost implications of leveraging a regional distribution center for the international transportation of vaccines in seven African countries. This report outlines the economic issues that need to be addressed for such a …

This article, published in Vaccine, discusses the challenges of different approaches to developing and producing thermostable vaccines. Topics include the technical feasibility of improving vaccine thermostability and thus vaccine effectiveness …

PATH and its partners have been advancing innovative vaccine technologies for more than 30 years. This report outlines PATH's approach and capabilities. It also describes a number of individual vaccine technologies at various …

This document reports on a study of vaccine vial monitor (VVM) availability and use in developing countries in four regions. The study included three aspects: the total proportion of vaccines with VVMs in the regions with detailed information by …