Topic: Vaccine safety and performance
Total results with these characteristics: 206
- Immunize Canada
This partnership of nongovernmental, professional, health, consumer, government, and private-sector organizations aims to promote the understanding and use of vaccines recommended by Canada's National Advisory Committee on Immunization. Its goal is …
Author: Immunize Canada
- Immunogenicity and Safety of the Quadrivalent Human Papillomavirus Vaccine in HIV-1-Infected Women
This article, published in Clinical Infectious Diseases, shares findings of a trial involving 319 human immunodeficiency virus (HIV)-1-infected women in the United States, Brazil, and South Africa. The trial aimed to determine the immunogenicity …
Author: Kojic EM, Kang M, Cespedes MS, et al.
- Immunogenicity of a Monovalent 2009 Influenza A(H1N1) Vaccine in Infants and Children: A Randomized Trial
This article, published in The Journal of the American Medical Association, details a randomized, observer-blind, age-stratified, parallel group study assessing two doses of an inactivated, split-virus 2009 influenza A(H1N1) vaccine in healthy …
Author: Nolan T, McVernon J, Skeljo M, et al.
- The Impact of 7-Valent Pneumococcal Conjugate Vaccine on Invasive Pneumococcal Disease: A Literature Review
This article, published in Advances in Therapy, describes results from a literature review of 37 articles from Australia, western Europe, and North America reporting impact data on invasive pneumococcal disease (IPD) following the introduction of …
Author: Myint TTH, Madhava H, Balmer P, et al.
- Impact of Pneumococcal Conjugate Vaccines on Nasopharyngeal Carriage and Invasive Disease Among Unvaccinated People: Review of Evidence on Indirect Effects
This article, published in Vaccine, summarizes the evidence for the indirect effect of pneumococcal conjugate vaccine on vaccine-type pneumococcal disease and its correlation with changes in carriage among unvaccinated populations.
Author: Davis SM, Deloria-Knoll M, Kassa HT, O'Brien KL
- The Impact of Protein-Conjugate Polysaccharide Vaccines: An Endgame for Meningitis?
The impact of conjugate polysaccharide vaccines on disease is largely due to their effectiveness against asymptomatic carriage of bacteria. This reduces transmission, resulting in herd immunity; however, the effect on carriage can result in the …
Author: Maiden MCJ
- Impact of Rotavirus Vaccination in Australian Children Below 5 Years of Age: A Database Study
This article, published in Human Vaccines & Immunotherapeutics, reports on a study that compared rotavirus hospitalization rates in children less than five years of age before and after the introduction of the rotavirus vaccine Rotarix® in …
Author: Pendleton A, Galic M, Clarke C, et al.
- Impact of Rotavirus Vaccination in Germany: Rotavirus Surveillance, Hospitalization, Side Effects and Comparison of Vaccines
This article, published in the Pediatric Infectious Disease Journal, examines the impact of national introduction of rotavirus vaccination in Germany. Rotavirus-related hospital admissions of children under one year of age decreased by 60 percent in …
Author: Uhlig U, Kostev K, Schuster V, Koletzko S, Uhlig HH
- Impact of Rotavirus Vaccine on Childhood Diarrheal Hospitalization Following Introduction Into the South African Public Immunization Program
This article, published in the Pediatric Infectious Disease Journal, describes a study in South Africa that demonstrated dramatic decreases in diarrhea-related hospitalizations in infants and young children in both rural and urban settings in the …
Author: Msimang VMY, Page N, Groome MJ, et al.
- Influenza Vaccine for Pregnant Women in Resource-Constrained Countries: A Review of the Evidence to Inform Policy Decisions
While influenza vaccination of pregnant women may be justified on the basis of preventing maternal disease alone, demonstrating additional benefits to the newborn is important to inform policy decisions in areas with limited resources and many …
Author: Ortiz JR, Englund JA, Neuzil KM
- Intussusception After Rotavirus Vaccines Reported to US VAERS, 2006-2012
This article, published in Pediatrics, describes investigators' assessment of intussusception events reported to the Vaccine Adverse Event Reporting System from 2006 through 2012, following the respective introductions of RotaTeq® (Merck & …
Author: Haber P, Patel M, Pan Y, et al.
- Intussusception Following Rotavirus Vaccine Administration: Post-Marketing Surveillance in the National Immunization Program in Australia
This article, published in Vaccine, reports that surveillance conducted following routine rotavirus vaccination in Australia did not find an overall increase in intussusception with use of RotaTeq® (Merck & Co., Inc.) and Rotarix® …
Author: Buttery JP, Danchin MH, Lee KJ, et al.
- Intussusception Risk after Rotavirus Vaccination in U.S. Infants
This article, published in the New England Journal of Medicine, reports on a study about the potential increased risk of intussusception after rotavirus vaccination with RotaTeq (RV5, a pentavalent vaccine) and Rotarix (RV1, a monovalent vaccine) …
Author: Yih WK, Lieu TA, Kulldorff M, et al.
- Intussusception Risk and Health Benefits of Rotavirus Vaccination in Mexico and Brazil
This article, published in The New England Journal of Medicine, assesses the association of the monovalent rotavirus vaccine (RV1) with intussusception after routine immunization of infants in Mexico and Brazil. The authors found that RV1 was …
Author: Patel MM, López-Collada VR, Bulhões MM, et al.
- Investigating Live Attenuated Influenza Vaccine Efficacy in Senegal
This fact sheet describes a Phase 3 clinical study that PATH and its partners are conducting in Senegal to evaluate the clinical efficacy of a seasonal, trivalent live attenuated influenza vaccine (LAIV). By providing evidence on how well this type …
- IPV Introduction, OPV Withdrawal and Routine Immunization Strengthening
This web page contains the rationale for and resources related to the introduction of inactivated polio vaccine (IPV), withdrawal of oral polio vaccine (OPV), and routine immunization strengthening. It provides five in-depth modules covering issues …
Author: World Health Organization
- The Journey of Your Child's Vaccine
This infographic provides an overview of how new vaccines are developed, approved, and manufactured, how they are added to the United States' childhood immunization schedule, and how vaccine safety continues to be monitored after introduction.
Author: US Centers for Disease Control and Prevention
- A Live Attenuated Influenza A(H5N1) Vaccine Induces Long-Term Immunity in the Absence of a Primary Antibody Response
This article, published in The Journal of Infectious Diseases, reports on a study on whether two influenza A(H5N1) live attenuated vaccines for pandemic use (pLAIVs) primed or established long-lasting immunity that could be detected by …
Author: Talaat KR, Luke CJ, Khurana S, et al.
- Long-Term Immunogenicity of Measles Vaccine After Coadministration with Live Attenuated Japanese Encephalitis Vaccine
This follow-up study to PATH's original coadministration trial demonstrated that measles seroprotection rates were still high one year post-vaccination among infants who originally seroconverted for measles.
- Maternal Immunisation in Developing Countries
This article, published in Vaccine, discusses the benefits and challenges of implementing maternal immunization as a method of preventing infections in the developing world. Specifically, the article discusses the high incidence of pneumococcal …
Author: Greenwood B
- Maternal Immunization Against Viral Disease
This article, published in Vaccine, discusses the advantages and disadvantages of maternal immunization to augment the protective effect of maternal antibody against many viral diseases in the young infant. The authors also present more specific …
Author: Englund J, Glezen WP, Piedra PA
- Maternal Immunization: US FDA Regulatory Considerations
Vaccination of pregnant women provides important health benefits to both mother and infant, and has been an important disease-prevention strategy in these two groups. However, since pregnant women are usually excluded from participation in clinical …
Author: Gruber MF
- Meeting of the Global Advisory Committee on Vaccine Safety, December 2010: Rotavirus Vaccine and Intussusception
This article, from the Weekly Epidemiological Record, reports on the outcome of a meeting of the World Health Organization's independent, authoritative vaccine safety committee where they reviewed postmarketing surveillance that indicated the …
Author: World Health Organization
- Meningococcal Vaccines: Current Issues and Future Strategies
The authors of this article, published in Drugs, provide an overview of the history and current state of meningococcal vaccines. They also review issues related to the vaccines that still need to be addressed including duration of protection, …
Author: Cohn AC, Harrison LH
- Meningococcal Vaccines: What You Need to Know
This fact sheet provides information on meningococcal vaccines, including who should get the vaccine, vaccine-associated risks, and where you can learn more about meningococcal disease and vaccines.
Author: US Centers for Disease Control and Prevention