Two innovative mechanisms have been used to accelerate the development of low-price supply lines for conjugate vaccines. The Meningitis Vaccine Project is a so-called push mechanism that facilitated technology transfer to an Indian company to …

As the development of malaria vaccines accelerates, work is also underway on the policy front to pave the way for decisions on possible malaria vaccine use. Early planning is crucial to the successful adoption and introduction of a vaccine. To …

On behalf of Partnerships for Health Reform Plus, this paper evaluates public and private provision of health care services in low- and middle-income developing countries through a framework intended to help governments analyze the costs and …

In December 2010, global health leaders committed to making the next 10 years the Decade of Vaccines - to ensure discovery, development, and delivery of lifesaving vaccines globally, especially to the poorest countries. This special series of …

This section on the GAVI Alliance's website provides information about the pilot pneumococcal Advance Market Commitment (AMC), which is an innovative funding mechanism. It incentivizes vaccine makers to produce suitable and affordable vaccines for …

Investigators developed a model using epidemiological evidence, country-specific cost estimates, and vaccine efficacy data to estimate the cost-effectiveness of rotavirus vaccination and determined that it would reduce health care expenses and …

This 16-page paper, on behalf of Abt Associates, was written to help analysts, stakeholders, and decision-makers give full consideration to including immunizations as a major element of poverty reduction strategies developed in the Heavily …

This article, published in Health Affairs, discusses a number of promising and innovative approaches that are being explored to increase the incentives and reduce the risks of investing in vaccines for developing countries. These approaches aim …

This document outlines procedures to assess the acceptability of vaccines in order to verify that they meet the specifications of the relevant UN agency for procurement and that they are produced in accordance with the principles and specifications …

Several vaccines that have come to market, including the rotavirus, pneumococcal conjugate, and human papillomavirus vaccines, have the potential to bring large public health benefits to developing countries. This eight-page policy brief explains …

This report assesses global readiness to fight cervical cancer using new approaches and new technologies, especially in regions where the disease is a common killer. It underscores the urgent need for the global community to prioritize cervical …

This article, published in Vaccine, projects the cost-effectiveness and health impact of rotavirus vaccines in countries eligible for support from the GAVI Alliance. The authors used a decision-analytic model to project the health outcomes and …

The authors of this article, published in Vaccine, determined the impact and cost-effectiveness of pneumococcal and rotavirus vaccination programs among children younge than five years of age in Uganda from the public health system perspective. They …

The authors of this article, published in Clinical Infectious Diseases, aimed to determine the potential impact and cost-effectiveness of a national rotavirus vaccination program in India. They compared the national rotavirus disease and cost burden …

The Optimize project, a collaboration between PATH and the World Health Organization, commissioned this white paper to examine the issues influencing vaccine producer willingness to advance, adopt, and commercialize value-added technologies for …

This article, published in the Bulletin of the World Health Organization, examines whether the reduced prices for rotavirus vaccine are affordable enough to facilitate access to the vaccine where it is most needed. The study points to the rotavirus …

On behalf of Partnerships for Health Reform, this report analyzes available information on financing immunization programs in developing countries, and focuses cost implications of new vaccine introduction, government and donor funding trends, …

This website is designed to provide easy access to science-based information for health program managers and decision-makers seeking to prevent cervical cancer in developing countries and low-resource settings. The wide range of materials appearing …

Lack of information on both the price and the different product characteristics of vaccines limits countries’ ability to operate affordable and effective immunization programs. This report aims to remedy some of the existing knowledge gaps by …

Investigators estimated the costs related to rotavirus disease in Uzbekistan and determined that a vaccine would be cost-effective, while also drastically reducing hospitalizations and deaths. This article was published in the journal Vaccine.

This special edition of the journal Vaccine broadens understanding of rotavirus disease burden, which is responsible for almost half of acute diarrhea hospitalizations among Asian children under five. In addition to documenting rotavirus …

This online course is a practical tool designed to aid health care administrators in making evidence-based decisions regarding rotavirus vaccine introduction into national immunization programs. The module provides training on topics ranging from …

This article, published in Pharmacoeconomics, provides an overview of the clinical profile of rotavirus vaccine RIX4414 (Rotarix™) in the prevention of rotavirus gastroenteritis in developing countries, followed by a comprehensive review of …

This report focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals. It looks at the development and use of vaccines and the …

This technical report from the Roll Back Malaria Partnership shines a spotlight on recent trends in investments in malaria research and development (R&D). The report follows up on a 2005 study by the Malaria R&D Alliance to establish a …