This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

This article, published in Human Vaccines, reports on a study that aimed to characterize the immediate qualitative changes of hepatitis B vaccine caused by freeze exposure. The vaccine was subjected to freezing temperatures ranging from 0°C to …

Highly sensitive and reliable assays based on the quantitation of immunologically relevant component(s) in recombinant or whole parasite-based vaccines would facilitate pre-clinical and clinical phases and the monitoring of malaria vaccine …

This attractive PowerPoint show is an immunization advocacy tool designed to be adapted for different situations. Presenters are encouraged to insert their organizational logo, add or subtract pages, substitute images, or revise the text, depending …

COTS is an e-book, funded by the US Agency for International Development, designed to export the clinical, scientific, and public health expertise on cholera and shigellosis from the International Centre for Diarrhoeal Disease Research, …

Written by pediatrician and author Ari Brown, MD, this six-page handout addresses the concerns of vaccine-hesitant parents, including vaccine safety, autism, and alternative vaccination schedules.

This article, published in the New England Journal of Medicine, offers a comprehensive review of virologic, epidemiologic, and clinical data on influenza A(H1N1) virus infections during the 2009 pandemic and summarizes key issues for clinicians …

This PowerPoint presentation trains doctors and health care workers in areas where Japanese encephalitis is endemic on how to assess a patient presenting with acute encephalitis syndrome. This version has still images only; a version with video …

This presentation provides an overview of the clinical manifestations and diagnosis of encephalitis. This presentation can be adapted for your specific use.

This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …

This fact sheet provides an overview of the development and testing of malaria vaccine candidates through clinical trials, including an explanation of why trials are important and descriptions of each clinical trial phase.

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …

This issue brief is written for civil society leaders seeking to expand access to cervical cancer prevention and control resources in their communities. These resources include HPV vaccines for young adolescents and established and new screening and …

From the Bulletin of the World Health Organization, researchers evaluated the clinical case definition of acute encephalitis syndrome, which the standards use for identification of JE patients, to determine its sensitivity and specificity.

This fact sheet provides information on cold chain and logistics for vaccine delivery, including challenges for managing the cold chain, examples of effective cold chain management, and the costs associated with the cold chain.

This tool is a Microsoft Access-based software tool that helps cold chain managers and public health officers make strategic decisions about managing their cold chain equipment. It is accompanied by a user manual, a set of data collection …

Optimize—a collaboration between the World Health Organization and PATH—aims to employ technological and scientific advances by defining ideal specifications for health products and creating a flexible and robust vaccine supply chain …

This 68-page manual examines the origin and impact of rumors on immunization programmes in Uganda, Kenya, and Tanzania and provides practical advice about dealing with rumors.

This article, published in Clinical and Vaccine Immunology, describes the results of a Phase 1 trial of a trivalent, live attenuated enterotoxigenic Escherichia coli vaccine candidate, ACE527. The study indicated that ACE527 had a strong safety …

"A Promised Renewed" is a wide-ranging and ambitious initiative that seeks to unite a number of partners around the goal of ending preventable child deaths. This first annual progress report on child survival aims to stimulate public dialogue and …

This briefing paper underscores the burden of rotavirus disease and highlights the promise of vaccines to combat the virus as the global health community prepares for worldwide introduction.

This comprehensive kit is designed to help healthcare providers discuss immunization with their patients. The kit provides accessible information on everything from immunization recommendations to common questions and concerns.

These checklists and guides cover communication and mobilization aspects of routine immunization and disease surveillance, in addition to supplemental immunization for polio eradication.

This document provides a collection of checklists that serve as a quick-reference communications and social mobilization guide on aspects of routine immunization and disease surveillance, in addition to supplementary immunization for polio …

This comprehensive reference tool is intended to help program officers learn about, design, and implement effective research-driven communication programs.