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Region: Global

Total results with these characteristics: 982

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Challenges in Developing a Pediatric RSV Vaccine

There is currently no approved respiratory syncytial virus (RSV) vaccine, and the goal of preventing RSV-associated illness in the general population remains unmet. The authors of this article, published in Human Vaccines, discuss the challenges …

Author: Schickli JH, Dubovsky F, Tang RS

Published: 2009

Chapter 15: HPV Vaccine Use in the Developing World

The authors of this article, which is a chapter in a monograph published in Vaccine, argue that HPV vaccine should be introduced in the framework of comprehensive cervical cancer control, and offers an opportunity to bring together a wide range of …

Author: Kane MA, Sherris J, Coursaget P, Aguado T, Cutts F

Published: 2006

Chapter 25: Education, Training, and Communication for HPV Vaccines

The authors of this article, which is a chapter in a monograph published in Vaccine, purport that as HPV vaccines come to market, they will face education and training challenges similar to those of other new vaccines, along with HPV-specific …

Author: Sherris J, Friedman A, Wittet S, Davies P, Steben M, Saraiya M

Published: 2006

Characterization and Standardization of Sabin Based Inactivated Polio Vaccine: Proposal for a New Antigen Unit for Inactivated Polio Vaccines

To prepare for the post-eradication period of polio and meet expected demand for inactivated polio vaccine (IPV), the production capacity of wild-type IPV needs to increase. However, the strains used for this process require stringent containment …

Author: Westdijk J, Brugmans D, Martin J, et al.

Published: 2011

Characterization of a Thermostable Hepatitis B Vaccine Formulation

This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

Author: Braun LJ, Jezek J, Peterson S, et al.

Published: 2009

Characterization of the Freeze Sensitivity of a Hepatitis B Vaccine

This article, published in Human Vaccines, reports on a study that aimed to characterize the immediate qualitative changes of hepatitis B vaccine caused by freeze exposure. The vaccine was subjected to freezing temperatures ranging from 0°C to …

Author: Chen D, Tyagi A, Carpenter J, et al.

Published: 2009

A Chemiluminescent-Western Blot Assay for Quantitative Detection of Plasmodium falciparum Circumsporozoite Protein

Highly sensitive and reliable assays based on the quantitation of immunologically relevant component(s) in recombinant or whole parasite-based vaccines would facilitate pre-clinical and clinical phases and the monitoring of malaria vaccine …

Author: Kumar S, Zheng H, Sangweme DT, et al.

Published: 2013

Cholera Outbreak Training and Shigellosis (COTS) Program

COTS is an e-book, funded by the US Agency for International Development, designed to export the clinical, scientific, and public health expertise on cholera and shigellosis from the International Centre for Diarrhoeal Disease Research, …

Author: COTS Program

Clear Answers & Smart Advice About Your Baby’s Shots

Written by pediatrician and author Ari Brown, MD, this six-page handout addresses the concerns of vaccine-hesitant parents, including vaccine safety, autism, and alternative vaccination schedules.

Author: Brown A

Published: 2013

Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection

This article, published in the New England Journal of Medicine, offers a comprehensive review of virologic, epidemiologic, and clinical data on influenza A(H1N1) virus infections during the 2009 pandemic and summarizes key issues for clinicians …

Author: Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza

Published: 2010

Clinical Assessment of Children with Suspected Central Nervous System Infections

This PowerPoint presentation trains doctors and health care workers in areas where Japanese encephalitis is endemic on how to assess a patient presenting with acute encephalitis syndrome. This version has still images only; a version with video …

Author: Univerity of Liverpool Brain Infections Group

Published: 2008

Clinical Manifestations and Diagnosis of Encephalitis

This presentation provides an overview of the clinical manifestations and diagnosis of encephalitis. This presentation can be adapted for your specific use.

Author: PATH

Published: 2005

Clinical Performance and Safety of the ID Adapter, a Prototype Intradermal Delivery Technology for Vaccines, Drugs, and Diagnostic Tests

The authors of this article, published in Procedia in Vaccinology, discuss a Phase 1 clinical study conducted to evaluate the intradermal (ID) adapter, a prototype intradermal delivery aid, for safety and precision of injection. The authors present …

Author: Jarrahian C, Zehrung D, Saxon E, Griswold E, Klaff L

Published: 2012

Clinical Presentation of Meningococcal Disease in Childhood

This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …

Author: Sabatini C, Bosis S, Semino M, Senatore L, Principi N, Esposito S

Published: 2012

Clinical Trials: Steps in Malaria Vaccine Development

This fact sheet provides an overview of the development and testing of malaria vaccine candidates through clinical trials, including an explanation of why trials are important and descriptions of each clinical trial phase.

Author: PATH

Published: 2009

Clonal Properties of Meningococci From Epidemic Meningitis

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …

Author: Achtman M

Published: 1991

Coalition Building: A Cornerstone of National Advocacy, Policymaking and Effective Cervical Cancer Prevention Programs

This issue brief is written for civil society leaders seeking to expand access to cervical cancer prevention and control resources in their communities. These resources include HPV vaccines for young adolescents and established and new screening and …

Author: Cervical Cancer Action

A Cohort Study to Assess the New WHO Japanese Encephalitis Surveillance Standards

From the Bulletin of the World Health Organization, researchers evaluated the clinical case definition of acute encephalitis syndrome, which the standards use for identification of JE patients, to determine its sensitivity and specificity.

Author: Solomon T, Thao TT, Lewthwaite P, et al.

Published: 2008

Cold Chain and Logistics Management: An Essential Part of Safe and Effective Vaccination Programs

This fact sheet provides information on cold chain and logistics for vaccine delivery, including challenges for managing the cold chain, examples of effective cold chain management, and the costs associated with the cold chain.

Author: IMMUNIZATIONbasics

Published: 2008

Cold Chain Equipment Inventories

This fact sheet describes PATH’s work to develop and deploy a software tool called Cold Chain Equipment Manager to help vaccination programs manage equipment requirements, forecast equipment needs, and generate procurement lists. It includes a …

Author: PATH

Published: 2014

Cold Chain Equipment Manager

This tool is a Microsoft Access-based software tool that helps cold chain managers and public health officers make strategic decisions about managing their cold chain equipment. It is accompanied by a user manual, a set of data collection …

Author: PATH

Published: 2012

Cold Chain Technologies

This fact sheet describes PATH's work on cold chain technologies. PATH is working with manufacturers and country collaborators to advance passive cold chain equipment and refrigerators that keep vaccines cold without freezing, as well as solar …

Author: PATH

Published: 2013

Colonisation Endpoints in Streptococcus pneumoniae Vaccine Trials

This article, published in Vaccine, reviews recent developments in the area of using colonization as an endpoint for evaluating vaccine efficacy against Streptococcus pneumoniae. The authors also provide practical guidelines for estimation methods …

Author: Auranen K, Rinta-Kokko H, Goldblatt D, et al.

Published: 2013

Combating Antivaccination Rumors: Lessons Learned From Case Studies in East Africa

This 68-page manual examines the origin and impact of rumors on immunization programmes in Uganda, Kenya, and Tanzania and provides practical advice about dealing with rumors.

Author: UNICEF

Published: 2001

A Combination Vaccine Consisting of Three Live Attenuated Enterotoxigenic Escherichia coli Strains Expressing a Range of Colonization Factors and LTB is Well Tolerated and Immunogenic in a Placebo-Controlled Double-Blind Phase 1 Trial in Healthy Adults

This article, published in Clinical and Vaccine Immunology, describes the results of a Phase 1 trial of a trivalent, live attenuated enterotoxigenic Escherichia coli vaccine candidate, ACE527. The study indicated that ACE527 had a strong safety …

Author: Harro C, Sack D, Bourgeois AL, et al.

Published: 2011

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