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Disease: Influenza

Total results with these characteristics: 119

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Protecting Aluminum-Adjuvanted Vaccines From Freeze Damage

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global …

Author: PATH

Published: 2012

Public Health Response to Influenza A(H1N1) as an Opportunity to Build Public Trust

This commentary, published in the Journal of the American Medical Association, reviews the public health response to the 2009 influenza A(H1N1) pandemic and suggests how this situation provided an opportunity to build public trust in vaccines. …

Author: Larson HJ, Heymann DL

Published: 2010

PubMed Searches: Influenza

These pre-formatted PubMed searches will retrieve journal citations and available abstracts that address disease burden, vaccine efficacy and benefits, and model programs, among other relevant issues related to influenza. Documents may be ordered …

Author: Various

Report of the Second WHO Consultation on the Global Action Plan for Influenza Vaccines (GAP)

This report of the second World Health Organization Consultation on the Global Action Plan for Influenza Vaccines (GAP-II) held July 12 to 14, 2011, summarizes the overview of GAP activities in the first five years and proposed action points …

Author: World Health Organization

Published: 2012

Response to a Monovalent Influenza A (H1N1) 2009 Vaccine

This article, published in The New England Journal of Medicine, describes the methods, results, and conclusions from a randomized observer-blind, parallel-group trial evaluating two doses of an inactivated, split-virus 2009 influenza A(H1N1) vaccine …

Author: Greenberg ME, Lai MH, Hartel GF, et al.

Published: 2009

Response to the 2009 Pandemic: Effect on Influenza Control in Wealthy and Poor Countries

The authors of this article, published in Vaccine, address the hard choices that must be made early in a pandemic and explore the context in which these decisions were made during the 2009 influenza pandemic. They argue that the only way to assure …

Author: Monto AS, Black S, Plotkin SA, Orenstein WA

Published: 2011

Responses to Avian Influenza and State of Pandemic Readiness: Fourth Global Progress Report

This report focuses on progress with responses to avian influenza and with pandemic preparedness between June 2007 and June 2008. Where data allow, the report looks back over the last three years. It also: 1) describes international financial …

Author: United Nations System Influenza Coordinator, The World Bank

Published: 2008

Safety and Immunogenicity of a Novel Influenza Subunit Vaccine Produced in Mammalian Cell Culture

This article, published in the Journal of Infectious Diseases, describes a novel cell culture-derived influenza vaccine (CCIV) produced in Madin-Darby canine kidney cells. The Phase 3, multicenter study in Poland observed that CCIV was well …

Author: Szymczakiewicz-Multanowska A, Groth N, Bugarini R, et al.

Published: 2009

Safety and Immunogenicity of ASO3(B) Adjuvanted Split Virion Versus Non-adjuvanted Whole Virion H1N1 Influenza Vaccine in UK Children Aged 6 Months-12 Years: Open Label, Randomised, Parallel Group, Multicentre Study

This article, published through Online First of the British Medical Journal, details a study wherein researchers evaluated the safety, tolerability, and immunogenicity of an AS03(B)/oil-in-water emulsion-adjuvanted (AS03(B)) split-virion versus …

Author: Waddington CS, Walker WT, Oeser C, et al.

Published: 2010

Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review

This article, published in Pediatrics, reviews the existing literature on the safety of routine vaccines recommended for children in the United States. The authors found evidence that some vaccines are associated with serious adverse events; …

Author: Maglione MA, Das L, Raaen L, et al.

Published: 2014

Scientific Barriers to Developing Vaccines Against Avian Influenza Viruses

This review, published in Nature Reviews Immunology, discusses gaps in the knowledge of how avian influenza viruses work in humans and the the status of influenza vaccine development as of 2007. It also provides a general overview of the features of …

Author: Subbarao K, Joseph T

Published: 2007

Seasonal Flu

This web page provides information and resources for health professionals and the public on preventing and controlling influenza.

Author: US Centers for Disease Control and Prevention

Seasonal Influenza Vaccine Provision in 157 Countries (2004-2009) and the Potential Influence of National Public Health Policies

This article, published in Vaccine, details the results of a survey of global influenza vaccine supply covering 157 countries from 2004 to 2009. The authors find that global annual vaccine provision increased 72 percent to 449 million doses during …

Author: Palache A

Published: 2011

Stabilizing Influenza Vaccines

If a highly virulent pandemic strain were to emerge in today‚Äôs interconnected world, influenza has the potential to kill millions of people, especially in developing countries with limited to no resources for pandemic planning, preparedness, and …

Author: PATH

Published: 2013

State of the Art of New Vaccines: Research and Development

This document analyzes research and development activities for vaccines against infectious diseases of public health importance. Disease groups covered include diarrheal disease, sexually transmitted diseases, respiratory infections, bacterial …

Author: World Health Organization

Published: 2006

State of the World's Vaccines and Immunization, Third Edition

This report focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals. It looks at the development and use of vaccines and the …

Author: World Health Organization, United Nations Children's Fund, World Bank

Published: 2009

Subunit Influenza Vaccines Produced From Cell Culture or in Embryonated Chicken Eggs: Comparison of Safety, Reactogenicity, and Immunogenicity

This study, published in the Journal of Infectious Diseases, assessed the safety, reactogenicity, and immunogenicity of an injectable cell culture-derived influenza vaccine, compared with those of an injectable egg-based trivalent inactivated …

Author: Reisinger KS, Block SL, Izu A, Groth N, Holmes SJ

Published: 2009

Summary of Vaccine Stability Data

These documents provide stability data as of November 2012 on commonly used, licensed vaccines and stability data as of May 2012 from available data on novel, investigational vaccine formulations. Data are sorted by vaccine in a table format in both …

Author: PATH, Working in Tandem Ltd.

Published: 2012

Temperature Sensitivity of Vaccines

This document addresses issues regarding potential exposure of temperature-sensitive vaccines to freezing temperatures and provides updated information on vaccine vial monitors, as well as a discussion of future advances in cold chain technology.

Author: World Health Organization

Published: 2006

Toward a Universal Influenza Virus Vaccine: Prospects and Challenges

This article, published in Annual Review of Medicine, summarizes advances in the field of universal influenza vaccine development. It focuses on novel vaccine designs that have yielded promising preclinical and clinical data. ABSTRACT ONLY. (Learn …

Author: Pica N, Palese P

Published: 2013

Trial of 2009 Influenza A (H1N1) Monovalent MF59-Adjuvanted Vaccine

This article, published by The New England Journal of Medicine, details the findings of a single-center study in the United Kingdom to test the monovalent influenza A/California/2009 (H1N1) surface-antigen vaccine, in both MF59-adjuvanted and …

Author: Clark TW, Pareek M, Hoschler K, et al.

Published: 2009

Trial of Influenza A(H1N1) 2009 Monovalent MF59-Adjuvanted Vaccine -- Preliminary Report

This article, published in The New England Journal of Medicine, describes the methods, results, and conclusions from a single-center study to test the monovalent influenza A/California/2009 (H1N1) surface-antigen vaccine. The study, conducted in the …

Author: Clark TW, Pareek M, Hoschler K, et al.

Published: 2009

Understanding Influenza Vaccine Effectiveness in Senegal

This fact sheet describes a Phase 4, post-licensure influenza vaccine effectiveness study that PATH and its partners are conducting in Senegal. The study seeks to better understand the extent of the influenza disease burden in tropical Africa, …

Author: PATH

Published: 2011

Understanding Influenza Vaccine Performance Among Children in Senegal

This fact sheet describes a Phase 2 influenza vaccine clinical study that PATH and its partners are conducting in Senegal. The study seeks to better understand the performance of seasonal influenza vaccines in a tropical, low-resource region of the …

Author: PATH

Published: 2013

Understanding Thimerosal, Mercury, and Vaccine Safety

This fact sheet explains what thimerosal is and why it is used as a preservative in some multi-dose vials of influenza vaccine, and highlights conclusions from studies examining thimerosal safety in vaccines.

Author: US Centers for Disease Control and Prevention

Published: 2012

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