The mission of the National Center for Immunization and Respiratory Diseases (NCIRD) is the prevention of disease, disability, and death through immunization and by control of respiratory and related diseases. This web page contains additional …

This article, which appeared in Drugs of Today, provides an overview of currently available pneumococcal conjugate vaccines (PCVs) and outlines several new approaches in the pipeline for PCVs designed to meet needs in the developing world. ABSTRACT …

This article, published in Vaccine, reviews the state of the current evidence on conjugate vaccines and identifies important areas for further study, in order to inform the debate regarding the best use of these vaccines, which not only prevent …

This article, published in Clinical and Vaccine Immunology, describes research conducted at Children’s Hospital Boston which showed that killing cells of a noncapsulated strain of Streptococcus pneumoniae with chloroform, tricholorethylene, or …

Published in the journal Tropical Medicine and International Health, the purpose of this study was to assess the importance of disabilities following pneumococcal and Hib meningitis in The Gambia. 257 children aged 0-12 years hospitalized between …

This paper, published in Pediatric Health, provides an overview of the efforts that PATH is undertaking to advance the development of new vaccines against Streptococcus pneumoniae that can be low-cost and accessible for the …

This article, published in The Lancet, summarizes the past ten years of research on pneumococcal pneumonia. The article includes a review of the epidemiology, genetics, and immunology of the disease, as well as approaches to clinical diagnosis, …

This article, published in Morbidity and Mortality Weekly Report, analyzes data for 2002 to 2008 from the Pediatric Bacterial Meningitis (PBM) Surveillance Network, which collects information on laboratory-confirmed bacterial meningitis cases among …

This article, published in Vaccine, aims to provide a framework for the global evaluation of pneumococcal conjugate vaccines by reviewing the pharmacoeconomic perspective in Latin America, highlighting both the strengths and weaknesses, while also …

Pneumolysin is a protein toxin produced by virtually all invasive strains of S. pneumoniae and is considered an important virulence factor. It is immunogenic and has the potential to be a new vaccine antigen offering broad serotype-independent …

This book provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on vaccine-preventable diseases. In addition to chapters on more general vaccine-related topics, it …

This standard reference is frequently updated with the latest information on vaccine-preventable diseases.

Through the PneumoACTION website, the International Vaccine Access Center at Johns Hopkins University offers a vast array of resources about pneumococcal disease, financing options for vaccines and immunization, and pneumococcal vaccines. …

This section on the GAVI Alliance's website provides information about the pilot pneumococcal Advance Market Commitment (AMC), which is an innovative funding mechanism. It incentivizes vaccine makers to produce suitable and affordable vaccines for …

Published in The Lancet, this study assessed the efficacy of a novel vaccine that contained polysaccharides from 11 different Streptococcus pneumoniae serotypes each conjugated to Haemophilus influenzae-derived protein D in prevention of acute …

This article, published in Weekly Epidemiological Record, is a summary of pneumococcal disease and its burden, as well as the official World Health Organization (WHO) position on use of conjugate vaccines in a global context. In 2012, the …

Published in the journal Pediatric Drugs, this article reviews data from trials using the pneumococcal conjugate vaccine to determine the vaccine's ability to reduce and/or prevent Streptococcus pneumoniae infection. ABSTRACT ONLY. (Learn how users …

This web page provides an overview of pneumococcal disease and vaccines against it. This page also provides links to World Health Organization (WHO) position papers on the disease and other related WHO resources.

This article, published in Vaccine, asserts that contrary to the common belief held by many pediatricians, the most important pneumococcal infections are of the respiratory tract and not invasive diseases. The authors explain that development …

This article, published in Nature Genetics, describes a study using array-based sequencing of 62 isolates from a US national monitoring program to study five independent instances of vaccine escape recombination. The study observations clarify the …

This fact sheet provides information for healthcare professionals on the pneumococcal polysaccharide vaccine, including vaccination recommendations from the US Centers for Disease Control and Prevention.

This web page offers descriptions of pneumococcal disease and vaccines, links to resources, frequently asked questions, and other related information.

This article, published in the Weekly Epidemiological Record, summarizes the World Health Organization's (WHO's) recommendations on pneumococcal vaccines and related issues, including disease surveillance, epidemiology, and studies to evaluate …

This fact sheet provides an overview of the causes, means of transmission, symptoms, risk factors, treatment, prevention, and economic costs of pneumonia. Also outlined is the World Health Organization's action plan to prevent and treat pneumonia, …

This report focuses on the huge potential to narrow the child survival gap between the richest and the poorest by focusing on pneumonia and diarrhea—the two primary killers of children under the age of five. It includes a review of the current …