Resource type: Peer-reviewed journal
Total results with these characteristics: 611
- Changes in Neisseria meningitidis Disease Epidemiology in the United States, 1998-2007: Implications for Prevention of Meningococcal Disease
This article, published in Clinical Infectious Diseases, describes the epidemiologic landscape of meningococcal disease in the United States from 1998 to 2007, including an analysis of the disease before and during the implementation of adolescent …
Author: Cohn AC, MacNeil JR, Harrison LH, et al.
- The Changing Epidemiology of Meningococcal Disease in North America 1945–2010
The epidemiology of Invasive Meningococcal Disease (IMD) is distinct in the United States and Canada compared with other countries. This review, published in Human Vaccines & Immunotherapeutics, describes the incidence, mortality, and …
Author: Baccarini C, Ternouth A, Wieffer H, Vyse A
- Chapter 15: HPV Vaccine Use in the Developing World
The authors of this article, which is a chapter in a monograph published in Vaccine, argue that HPV vaccine should be introduced in the framework of comprehensive cervical cancer control, and offers an opportunity to bring together a wide range of …
Author: Kane MA, Sherris J, Coursaget P, Aguado T, Cutts F
- Chapter 25: Education, Training, and Communication for HPV Vaccines
The authors of this article, which is a chapter in a monograph published in Vaccine, purport that as HPV vaccines come to market, they will face education and training challenges similar to those of other new vaccines, along with HPV-specific …
Author: Sherris J, Friedman A, Wittet S, Davies P, Steben M, Saraiya M
- Characterization and Standardization of Sabin Based Inactivated Polio Vaccine: Proposal for a New Antigen Unit for Inactivated Polio Vaccines
To prepare for the post-eradication period of polio and meet expected demand for inactivated polio vaccine (IPV), the production capacity of wild-type IPV needs to increase. However, the strains used for this process require stringent containment …
Author: Westdijk J, Brugmans D, Martin J, et al.
- Characterization of a Thermostable Hepatitis B Vaccine Formulation
This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …
Author: Braun LJ, Jezek J, Peterson S, et al.
- Characterization of the Freeze Sensitivity of a Hepatitis B Vaccine
This article, published in Human Vaccines, reports on a study that aimed to characterize the immediate qualitative changes of hepatitis B vaccine caused by freeze exposure. The vaccine was subjected to freezing temperatures ranging from 0°C to …
Author: Chen D, Tyagi A, Carpenter J, et al.
- A Chemiluminescent-Western Blot Assay for Quantitative Detection of Plasmodium falciparum Circumsporozoite Protein
Highly sensitive and reliable assays based on the quantitation of immunologically relevant component(s) in recombinant or whole parasite-based vaccines would facilitate pre-clinical and clinical phases and the monitoring of malaria vaccine …
Author: Kumar S, Zheng H, Sangweme DT, et al.
- Climate Drives the Meningitis Epidemics Onset in West Africa
This study, published in PLoS Medicine, provides a clear, quantitative demonstration of the connections that exist between major meningococcal meningitis (MCM) epidemics and regional climate variability in Africa. This statistically robust …
Author: Sultan B, Labadi K, Guégan JF, Janicot S
- Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
This article, published in the New England Journal of Medicine, offers a comprehensive review of virologic, epidemiologic, and clinical data on influenza A(H1N1) virus infections during the 2009 pandemic and summarizes key issues for clinicians …
Author: Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza
- Clinical Consequences of Rotavirus Acute Gastroenteritis in Europe, 2004-2005: The REVEAL Study
After a multicenter study in several European countries, investigators determined that acute gastroenteritis caused by rotavirus resulted in more hospitalizations and emergency department visits than acute gastroenteritis from another cause. This …
Author: Guiaquinto C, Van Damme P, Huet F, et al.
- Clinical Performance and Safety of the ID Adapter, a Prototype Intradermal Delivery Technology for Vaccines, Drugs, and Diagnostic Tests
The authors of this article, published in Procedia in Vaccinology, discuss a Phase 1 clinical study conducted to evaluate the intradermal (ID) adapter, a prototype intradermal delivery aid, for safety and precision of injection. The authors present …
Author: Jarrahian C, Zehrung D, Saxon E, Griswold E, Klaff L
- Clinical Presentation of Meningococcal Disease in Childhood
This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …
Author: Sabatini C, Bosis S, Semino M, Senatore L, Principi N, Esposito S
- Clinical Trial to Evaluate Safety and Immunogenicity of an Oral Inactivated Enterotoxigenic Escherichia coli Prototype Vaccine Containing CFA/I Overexpressing Bacteria and Recombinantly Produced LTB/CTB Hybrid Protein
This article, published in Vaccine, describes the results of a randomized, comparator controlled, double-blind Phase 1 trial in 60 Swedish adults testing a prototype of a new oral vaccine candidate against enterotoxigenic Escherichia coli (ETEC) …
Author: Lundgren A, Leach S, Tobias J, et al.
- Clonal Properties of Meningococci From Epidemic Meningitis
This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …
Author: Achtman M
- Clonal Waves of Neisseria Colonisation and Disease in the African Meningitis Belt: Eight-Year Longitudinal Study in Northern Ghana
This study, published in PLoS Medicine, aimed to determine how levels of colonization with different bacterial meingococcal serogroups change over time, and how the patterns of disease relate to such changes in the Kassena-Nankana District of …
Author: Leimkugel J, Hodgson A, Forgor AA, et al.
- Clones of Neisseria meningitidis Strains in Mali
This article, published in Médecine et Maladies Infectieuses, provides an overview of a cross-sectional, descriptive study to identify strains of Neisseria meningitidis isolated from 2005 to 2007 in Mali. Neisseria meningitidis appeared in 144 …
Author: Guindo I, Coulibaly A, Dao S, et al.
- A Cohort Study to Assess the New WHO Japanese Encephalitis Surveillance Standards
From the Bulletin of the World Health Organization, researchers evaluated the clinical case definition of acute encephalitis syndrome, which the standards use for identification of JE patients, to determine its sensitivity and specificity.
Author: Solomon T, Thao TT, Lewthwaite P, et al.
- Colonisation Endpoints in Streptococcus pneumoniae Vaccine Trials
This article, published in Vaccine, reviews recent developments in the area of using colonization as an endpoint for evaluating vaccine efficacy against Streptococcus pneumoniae. The authors also provide practical guidelines for estimation methods …
Author: Auranen K, Rinta-Kokko H, Goldblatt D, et al.
- A Combination Vaccine Consisting of Three Live Attenuated Enterotoxigenic Escherichia coli Strains Expressing a Range of Colonization Factors and LTB is Well Tolerated and Immunogenic in a Placebo-Controlled Double-Blind Phase 1 Trial in Healthy Adults
This article, published in Clinical and Vaccine Immunology, describes the results of a Phase 1 trial of a trivalent, live attenuated enterotoxigenic Escherichia coli vaccine candidate, ACE527. The study indicated that ACE527 had a strong safety …
Author: Harro C, Sack D, Bourgeois AL, et al.
- Community Diarrhea Incidence Before and After Rotavirus Vaccine Introduction in Nicaragua
This article, published in the American Journal of Tropical Medicine and Hygiene, reports on a study that compared the incidence of diarrhea before and after the introduction of the pentavalent rotavirus vaccine in Leon, Nicaragua. The results …
Author: Becker-Dreps S, Meléndez M, Liu L, et al.
- Community Perceptions of Malaria and Vaccines in the South Coast and Busia Regions of Kenya
Malaria is a leading cause of morbidity and mortality in children younger than 5 years in Kenya. Within the context of planning for a vaccine to be used alongside existing malaria control methods, this study, published in Malaria …
Author: Ba-Nguz A, Bingham A, Collymore Y, et al.
- Community Perceptions of Malaria and Vaccines in Two Districts of Mozambique
Malaria is a leading cause of mortality and morbidity in Mozambique, with nearly three-quarters of the country’s malaria-related deaths occurring in children younger than five years. A malaria vaccine is not yet available, but planning is …
Author: Bingham A, Gaspar F, Lancaster K, Conjera J, Collymore Y, Ba-Nguz A
- Comparative Evaluation of the Potential Impact of Rotavirus Versus HPV Vaccination in GAVI-Eligible Countries: A Preliminary Analysis Focused on the Relative Disease Burden
This article, published in BMC Infectious Diseases, reports on a study that aimed to provide early insight into how the comparative impact of different new vaccines could be assessed in resource-poor settings with respect to affordability, …
Author: Kim SY, Sweet S, Chang J, Goldie SJ
- Comparative Review of Three Cost-Effectiveness Models for Rotavirus Vaccines in National Immunization Programs: A Generic Approach Applied to Various Regions in the World
This article, published in BMC Medicine, critically reviews available cost-effectiveness models for rotavirus vaccination, comparing their designs using a standardized approach and studying the similarities and differences in cost-effectiveness …
Author: Postma MJ, Jit M, Rozenbaum MH, Standaert BA, Tu HA, Hutubessy RCW