The authors of this article, which is a chapter in a monograph published in Vaccine, argue that HPV vaccine should be introduced in the framework of comprehensive cervical cancer control, and offers an opportunity to bring together a wide range of …

The authors of this article, which is a chapter in a monograph published in Vaccine, purport that as HPV vaccines come to market, they will face education and training challenges similar to those of other new vaccines, along with HPV-specific …

To prepare for the post-eradication period of polio and meet expected demand for inactivated polio vaccine (IPV), the production capacity of wild-type IPV needs to increase. However, the strains used for this process require stringent containment …

This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

This article, published in Human Vaccines, reports on a study that aimed to characterize the immediate qualitative changes of hepatitis B vaccine caused by freeze exposure. The vaccine was subjected to freezing temperatures ranging from 0°C to …

Highly sensitive and reliable assays based on the quantitation of immunologically relevant component(s) in recombinant or whole parasite-based vaccines would facilitate pre-clinical and clinical phases and the monitoring of malaria vaccine …

This study, published in PLoS Medicine, provides a clear, quantitative demonstration of the connections that exist between major meningococcal meningitis (MCM) epidemics and regional climate variability in Africa. This statistically robust …

This article, published in the New England Journal of Medicine, offers a comprehensive review of virologic, epidemiologic, and clinical data on influenza A(H1N1) virus infections during the 2009 pandemic and summarizes key issues for clinicians …

After a multicenter study in several European countries, investigators determined that acute gastroenteritis caused by rotavirus resulted in more hospitalizations and emergency department visits than acute gastroenteritis from another cause. This …

This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …

This article, published in Vaccine, describes the results of a randomized, comparator controlled, double-blind Phase 1 trial in 60 Swedish adults testing a prototype of a new oral vaccine candidate against enterotoxigenic Escherichia coli (ETEC) …

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …

This study, published in PLoS Medicine, aimed to determine how levels of colonization with different bacterial meingococcal serogroups change over time, and how the patterns of disease relate to such changes in the Kassena-Nankana District of …

This article, published in Médecine et Maladies Infectieuses, provides an overview of a cross-sectional, descriptive study to identify strains of Neisseria meningitidis isolated from 2005 to 2007 in Mali. Neisseria meningitidis appeared in 144 …

From the Bulletin of the World Health Organization, researchers evaluated the clinical case definition of acute encephalitis syndrome, which the standards use for identification of JE patients, to determine its sensitivity and specificity.

This article, published in Clinical and Vaccine Immunology, describes the results of a Phase 1 trial of a trivalent, live attenuated enterotoxigenic Escherichia coli vaccine candidate, ACE527. The study indicated that ACE527 had a strong safety …

Malaria is a leading cause of morbidity and mortality in children younger than 5 years in Kenya. Within the context of planning for a vaccine to be used alongside existing malaria control methods, this study, published in Malaria …

Malaria is a leading cause of mortality and morbidity in Mozambique, with nearly three-quarters of the country’s malaria-related deaths occurring in children younger than five years. A malaria vaccine is not yet available, but planning is …

This article, published in BMC Medicine, critically reviews available cost-effectiveness models for rotavirus vaccination, comparing their designs using a standardized approach and studying the similarities and differences in cost-effectiveness …

Published in Health Policy and Planning, this compares cost-of-illness (COI) with stated preference estimates of willingness-to-pay associated with shigellosis in a rural area of China to evaluate the economic benefits of disease …

This article, published in the journal Vaccine, presents data generated through a PATH-supported study that demonstrated safe and immunogenic coadministration of measles vaccine and the live, attenuated japanese …

The Meningitis Vaccine Project (MVP) was established with the goal of developing, testing, licensing, and introducing an affordable group A meningococcal conjugate vaccine for Africa. The authors of this article, published in Vaccine, describe the …

Japanese encephalitis (JE) results in significant mortality and disability in children in Asia. In Indonesia, despite recognition of JE virus transmission, reports of human disease have been few and from limited geographic areas. Hospital-based …

This article, published in Tropical Medicine & International Health, asserts that surveillance systems and techniques for diagnosing bacterial meningitis and pneumococcal disease in the African meningitis belt have improved greatly over the …

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …