This article, published in Immunological Reviews, provides an overview of the barriers that have challenged and delayed the development of vaccines against respiratory syncytial virus (RSV) and identifies opportunities that could help overcome these …

This report highlights a study that uses a breakeven cost analysis to compare potential prices, wastage rates, and cold chain requirements for various human papillomavirus vaccine presentations. The results of this study provide insight into …

This graphic displays the malaria parasite's life cycle and highlights where three different types of vaccines could interrupt various stages of the life cycle.

This article, published in Vaccine, reports on a study that assessed the potential benefits of mortality reduction versus the risk of fatal intussusception when (a) the first dose of rotavirus vaccine was administered by 12 weeks of age compared …

This report summarizes the objectives of PATH's now-inactive Children's Vaccine Program, highlighting the program's earlier activities in several countries in Africa and Asia aimed at increasing access to livesaving vaccines.

This article, published in The Lancet, releases new global burden of disease data for Streptococcus pneumoniae (pneumococcus), a leading cause of bacterial pneumonia, meningitis, and sepsis in children worldwide. The results also include data at the …

This presentation, given at the 2006 meeting of the American Society for Tropical Medicine and Hygiene, provides an overview of JE disease burden and the activities of the PATH JE project.

This study, published in BMC Public Health, assesses the health outcomes and the economic impact of a universal rotavirus vaccination program with RotaTeq, a pentavalent rotavirus vaccine, against a no vaccination program in Spain. The study …

This article, published in the Pan American Journal of Public Health, estimates the annual burden of pneumonia, meningitis, and acute otitis media caused by pneumococcus in children less than five years of age in Latin America and the …

This report estimates the burden and costs of pneumococcal disease in Latin America and the Caribbean in order to inform national health authorities about disease burden and the economic value of implementing a pneumococcal …

This report discusses the work of PATH's Children's Vaccine Program and the Australian International Health Institute of the University of Melbourne to provide technical assistance with immunization programming to Cambodia, including the …

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

This article, published in Vaccine, discusses the challenges of achieving control of meningococcal disease in low- and middle-income countries. The authors argue that in low-income countries the main challenge is a lack of sufficient epidemiological …

The authors of this article, published in Vaccine, discuss how the introduction of vaccines against Neisseria meningitidis raises the question of whether disease caused by this obligate human bacterium can be controlled, eliminated, or even …

This web page provides an overview on cervical cancer and links to various related resources, including guidelines on cervical cancer prevention and treatment, a guide to essential clinical practice on comprehensive cervical cancer control, and …

This poster, presented at the 16th International Pathogenic Neisseria Conference in the Netherlands, discusses a study that aimed to provide preliminary information regarding meningococcal carriage in West Africa and on the effect on …

This market assessment aims to increase the awareness of biotechnology and pharmaceutical companies worldwide about the opportunities and potential markets that exist for low-cost and effective vaccines against enterotoxigenic Escherichia coli …

This technical six-minute animation explains what HPV is, shows how it infects human tissue, and how disease progresses. It also provides disease burden information specific to HPV and cervical cancer.

This interactive tool is designed for public health officials seeking guidance and resources related to developing evidence-based cervical cancer prevention programs in their countries. It includes video mini-lectures and other films, impact models, …

This article, published in the Bulletin of the World Health Organization, explores how scaled-up cervical cancer prevention activities, including introduction of the new HPV vaccines and increased access to precancer screening and treatment, can …

This report provides an in-depth look at PATH's work on cervical cancer prevention over the past two decades. It includes background on cervical cancer and HPV, and details about its work in four key areas: HPV vaccination, innovative approaches to …

This film in the BBC’s "Kill or Cure?" series uncovers the challenges of preventing and treating cervical cancer in Africa and highlights exciting new opportunities for dramatically reducing the toll of disease. The BBC crew follows Sarah …

After the World Health Assembly resolved in 1988 to eradicate wild poliovirus (WPV) transmission globally by 2000, dramatic progress in reducing polio cases and increasing the number of countries that interrupted indigenous WPV transmission was …

There is currently no approved respiratory syncytial virus (RSV) vaccine, and the goal of preventing RSV-associated illness in the general population remains unmet. The authors of this article, published in Human Vaccines, discuss the challenges …

This retrospective analysis, published in the Medical Journal of Australia, found a sustained and substantial decline in rotavirus hospitalizations as well as hospitalizations for diarrhea of any cause following national vaccine …