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Region: Global

Total results with these characteristics: 959

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Broadening the Age Restriction for Initiating Rotavirus Vaccination in Regions With High Rotavirus Mortality: Benefits of Mortality Reduction Versus Risk of Fatal Intussusception

This article, published in Vaccine, reports on a study that assessed the potential benefits of mortality reduction versus the risk of fatal intussusception when (a) the first dose of rotavirus vaccine was administered by 12 weeks of age compared …

Author: Patel MM, Clark AD, Glass RI, et al.

Published: 2009

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein

Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …

Author: Mann B, Thornton J, Heath R, et al.

Published: 2013

Burden of Disease Caused by Streptococcus Pneumoniae in Children Younger than 5 Years: Global Estimates

This article, published in The Lancet, releases new global burden of disease data for Streptococcus pneumoniae (pneumococcus), a leading cause of bacterial pneumonia, meningitis, and sepsis in children worldwide. The results also include data at the …

Author: O'Brien KL, Wolfson LJ, Watt JP, et al.

Published: 2009

Business and Cervical Cancer: Opportunities to Save Lives

This document is a five-page brief on cervical cancer prevention. It discusses the growing threat of human papillomavirus (HPV), early detection and screening, and available options for prevention and treatment. It also explores various …

Author: GBCHealth

Published: 2013

A Call to Action for the New Decade of Vaccines

This article, published in The Lancet, argues that there is a moral imperative to make vaccines widely available on an equitable basis. The authors lay out a call to action for the new decade of vaccines, which embraces four key elements. …

Author: Moxon ER, Das P, Greenwood B, et al.

Published: 2011

Calling the Shots: A Review of Global Immunisation Initiatives and Future Priorities

This report reviews the successes and challenges of current global immunization programs, with a particular focus on: pneumonia, diarrheal disease, polio, measles, and rubella. It argues that while there is much to be applauded, there is a funding …

Author: Royal College of Paediatrics and Child Health

Published: 2013

Can Successful Vaccines Teach Us How to Induce Efficient Protective Immune Responses?

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

Author: Lambert PH, Liu M, Siegrist CA

Published: 2005

Can We Defeat Meningococcal Disease in Low and Middle Income Countries?

This article, published in Vaccine, discusses the challenges of achieving control of meningococcal disease in low- and middle-income countries. The authors argue that in low-income countries the main challenge is a lack of sufficient epidemiological …

Author: Greenwood B, Chiarot E, MacLennan CA, O'Ryan M

Published: 2012

Can We, Should We, Eradicate the Meningococcus?

The authors of this article, published in Vaccine, discuss how the introduction of vaccines against Neisseria meningitidis raises the question of whether disease caused by this obligate human bacterium can be controlled, eliminated, or even …

Author: Maiden MC, Frosch M

Published: 2012

Care and Repair of Refrigerators for Vaccine Storage

This set of 17 training modules, developed for refrigerator technicians, includes handbooks on different types of refrigerators, as well as courses on service and repair techniques, repair work, and stocking spare parts, among others.

Author: World Health Organization

The Case for Developing and Deploying an Open Source Electronic Logistics Management Information System

This white paper makes the case for why logistics management information systems (LMIS) should be used to manage the distribution of pharmaceuticals, vaccines, and medical products. Health information users and stakeholders in low- and middle-income …

Author: PATH

Published: 2011

The Case for Investment in Enterotoxigenic Escherichia coli Vaccines

This market assessment aims to increase the awareness of biotechnology and pharmaceutical companies worldwide about the opportunities and potential markets that exist for low-cost and effective vaccines against enterotoxigenic Escherichia coli …

Author: PATH; BIO Ventures for Global Health

Published: 2011

Center for Vaccine Ethics & Policy

The Center for Vaccine Ethics & Policy is a program of the New York University Medical School's Division of Medical Ethics, The Wistar Institute Vaccine Center, and the Children’s Hospital of Philadelphia's Vaccine Education Center. Formed in …

Author: Center for Vaccine Ethics & Policy

Cervical Cancer Action: 2007 to 2014 . . . and Beyond

This briefing paper highlights Cervical Cancer Action's accomplishments and global milestones, engagements and country support, and plans for future investment. It includes a detailed timeline which spans from 2007 to 2013 and a map of the rapid …

Author: Cervical Cancer Action

Published: 2014

Cervical Cancer, Cervical Dysplasia, Genital Warts: The Pathogenesis and Clinical Outcomes of HPV Anogenital Infections

This technical six-minute animation explains what HPV is, shows how it infects human tissue, and how disease progresses. It also provides disease burden information specific to HPV and cervical cancer.

Author: Sanofi Pasteur MSD

Published: 2006

Cervical Cancer, Human Papillomavirus (HPV), and HPV vaccines: Key Points for Policy-Makers and Health Professionals

HPV vaccines address a critical public health need, and will be an important element of a comprehensive cervical cancer control strategy. Ensuring universal access to HPV vaccination, screening, and treatment services will be key to reducing the …

Author: World Health Organization

Published: 2008

Cervical Cancer Prevention Action Planner

This interactive tool is designed for public health officials seeking guidance and resources related to developing evidence-based cervical cancer prevention programs in their countries. It includes video mini-lectures and other films, impact models, …

Author: PATH

Published: 2012

Cervical Cancer Prevention and the Millennium Development Goals

This article, published in the Bulletin of the World Health Organization, explores how scaled-up cervical cancer prevention activities, including introduction of the new HPV vaccines and increased access to precancer screening and treatment, can …

Author: Wittet S, Tsu V

Published: 2008

Cervical Cancer Prevention at PATH: Two Decades of Progress Toward a World Free of HPV-Related Cancers

This report describes PATH's key cervical cancer prevention initiatives, which include providing technical assistance with human papillomavirus (HPV) vaccine program strategy and planning to low- and middle-income countries.

Author: PATH

Published: 2013

Challenges Faced by the Global Polio Eradication Initiative

After the World Health Assembly resolved in 1988 to eradicate wild poliovirus (WPV) transmission globally by 2000, dramatic progress in reducing polio cases and increasing the number of countries that interrupted indigenous WPV transmission was …

Author: Wassilak S, Orenstein W

Published: 2010

Challenges in Developing a Pediatric RSV Vaccine

There is currently no approved respiratory syncytial virus (RSV) vaccine, and the goal of preventing RSV-associated illness in the general population remains unmet. The authors of this article, published in Human Vaccines, discuss the challenges …

Author: Schickli JH, Dubovsky F, Tang RS

Published: 2009

Chapter 15: HPV Vaccine Use in the Developing World

The authors of this article, which is a chapter in a monograph published in Vaccine, argue that HPV vaccine should be introduced in the framework of comprehensive cervical cancer control, and offers an opportunity to bring together a wide range of …

Author: Kane MA, Sherris J, Coursaget P, Aguado T, Cutts F

Published: 2006

Chapter 25: Education, Training, and Communication for HPV Vaccines

The authors of this article, which is a chapter in a monograph published in Vaccine, purport that as HPV vaccines come to market, they will face education and training challenges similar to those of other new vaccines, along with HPV-specific …

Author: Sherris J, Friedman A, Wittet S, Davies P, Steben M, Saraiya M

Published: 2006

Characterization and Standardization of Sabin Based Inactivated Polio Vaccine: Proposal for a New Antigen Unit for Inactivated Polio Vaccines

To prepare for the post-eradication period of polio and meet expected demand for inactivated polio vaccine (IPV), the production capacity of wild-type IPV needs to increase. However, the strains used for this process require stringent containment …

Author: Westdijk J, Brugmans D, Martin J, et al.

Published: 2011

Characterization of a Thermostable Hepatitis B Vaccine Formulation

This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

Author: Braun LJ, Jezek J, Peterson S, et al.

Published: 2009

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