Browse resources

Region: Africa

Total results with these characteristics: 207

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Emergence of Serogroup X Meningococcal Disease in Africa: Need for a Vaccine

This article, published in Vaccine, describes how and why serogroup X meningococcal disease has emerged in Africa in recent years. It asserts that while no licensed vaccine is available against serogroup X meningococci, following the introduction of …

Author: Xie O, Pollard AJ, Mueller JE, Norheim G

Published: 2013

Emergency or Routine Vaccination Against Meningococcal Disease in Africa?

This comment, published in The Lancet, is based on a review of the study "Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa." The author concludes that …

Author: Peltola H

Published: 2000

Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa

This article, published in The Lancet, assessed the potential effects of different vaccination strategies against meningococcal disease using data from the 1997 meningococcal outbreak in northern Ghana. Using a simple mathematical model, …

Author: Woods CW, Armstrong G, Sackey SO, et al.

Published: 2000

Enterotoxigenic Escherichia coli in Developing Countries: Epidemiology, Microbiology, Clinical Features, Treatment, and Prevention

This article was published in Clinical Microbiology Reviews. ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial …

Author: Qadri F, Svennerholm AM, Faruque AS, Sack RB

Published: 2005

Environmental Risk and Meningitis Epidemics in Africa

This study, published in Emerging Infectious Diseases, provides evidence that the relationship between the environment and the location of meningitis epidemics is quantifiable. The study proposes a model based on environmental …

Author: Molesworth AM, Cuevas LF, Connor SJ, Morse AP, Thomson MC

Published: 2003

Epidemic Meningitis Due to Group A Neisseria Meningitidis in the African Meningitis Belt: A Persistent Problem With an Imminent Solution

This article, published in the journal Vaccine, emphasizes Group A Neisseria meningitidis as a health problem in Africa and disccuses the potential for a proactive control strategy for epidemic meningitis with the use of …

Author: LaForce FM, Ravenscroft N, Djingarey M, et al

Published: 2009

Epidemiology, Aetiology and Management of Childhood Acute Community-Acquired Pneumonia in Developing Countries--A Review

This article, published in the African Journal of Medicine and Medical Sciences, provides an overview of the causes of clinical pneumonia in developing countries, available vaccines for fighting pneumonia, and efforts underway and planned to expand …

Author: Falade AG, Ayede AI

Published: 2011

Epidemiology of Bacterial Meningitis in Niamey, Niger, 1981-96

This study, published in the Bulletin of the World Health Organization, used retrospective surveillance to identify cases of laboratory-diagnosed bacterial meningitis in Niamey, Niger, from 1981 to 1996. The study analyzed the cases …

Author: Campagne G, Schuchat A, Djibo S, et al.

Published: 1999

Estimating Diarrheal Illness and Deaths Attributable to Shigellae and Enterotoxigenic Escherichia coli Among Older Children, Adolescents, and Adults in South Asia and Africa

This article, published in PLOS Neglected Tropical Diseases, aims to quantify the overall burden of shigellosis and enterotoxigenic Escherichia coli (ETEC) diarrhea among older children, adolescents, and adults in Africa and South Asia, the two …

Author: Lamberti LM, Bourgeois AL, Fischer Walker CL, Black RE, Sack D

Published: 2014

Evaluating HPV Vaccination Pilots: Practical Experience From PATH

From 2006 to 2011, PATH conducted human papillomavirus (HPV) vaccination demonstration projects in India, Peru, Uganda, and Vietnam to provide evidence for decision-making about public-sector introduction of HPV vaccines. This report provides …

Author: PATH

Published: 2012

Evaluation of Cost-Effectiveness of Live Oral Pentavalent Reassortant Rotavirus Vaccine Introduction in Ghana

This article, published in Vaccine, estimates the cost-effectiveness of introducing the rotavirus vaccine RotaTeq® in Ghana. The authors estimated the average costs of treating children with diarrhea in the Ashanti region of Ghana as inpatients …

Author: Abbott C, Tiede B, Armah G, Mahmoud A

Published: 2012

Evaluation of Meningitis Surveillance Before Introduction of Serogroup A Meningococcal Conjugate Vaccine—Burkina Faso and Mali

Before the 2010 to 2011 introduction of the first serogroup A meningococcal conjugate vaccine developed solely for Africa (MenAfriVac), evaluations of the existing meningitis surveillance in Burkina Faso and Mali were conducted to assess the …

Author: US Centers for Disease Control and Prevention

Published: 2012

Evaluation of Serogroup A Meningococcal Vaccines in Africa: A Demonstration Project

This article, published in The Journal of Health, Population, and Nutrition, summarizes the general steps required for meningococcal vaccine development, reviews the use of immunogenicity criteria as a licensing strategy for new meningococcal …

Author: Soriano-Gabarró M, Rosenstein N, LaForce FM

Published: 2004

Evaluation of the Meningitis Epidemics Risk Model in Africa

This study, published in Epidemiology and Infection, evaluated an ecological model based on absolute humidity and land cover type to predict the location of meningitis epidemics in the Sahelian region known as the African Meningitis Belt. The …

Author: Savory EC, Cuevas LE, Yassin MA, et al.

Published: 2006

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

A malaria vaccine, deployed in combination with current malaria-control tools, could play an important role in future control and eventual elimination of malaria in Africa. This article, published in the New England Journal of Medicine (NEJM), …

Author: The RTS,S Clinical Trials Partnership

Published: 2011

Fragile Lives - Immunization at Risk

Hailed as "the greatest public health success story of all time," today childhood immunization faces obstacles never seen before. While immunization still saves three million young lives each year, millions more could be saved if there were enough …

Author: PATH, Barraclough Productions

Published: 2004

From Genomics to Surveillance, Prevention and Control: New Challenges for the African Meningitis Belt

This article, published in the Bulletin de la Société de Pathologie Exotique, summarizes an international conference held in Niamey, Niger, that brought together more than 100 delegates to assess the current meningitis situation in Africa, …

Author: Alonso JM, Bertherat E, Perea W, et al.

Published: 2006

Gambia Pneumococcal Vaccine Trial

This web page offers details of an important vaccine field efficacy study in Africa.

Author: US National Institute of Allergy and Infectious Diseases (NIAID)

Green Supply Chains: A Glimpse Into the Future?

This project Optimize evidence brief discusses the rationale for introducing net-zero energy systems into vaccine supply chains and describes the experiences and lessons learned in a demonstration project in Tunisia. Opportunities and challenges are …

Author: PATH, World Health Organization

Published: 2013

Haemophilus influenzae type b Conjugate Vaccine Impact Against Purulent Meningitis in Rwanda

Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. This study reviewed …

Author: Muganga N, Uwimana J, Fidele N, et al.

Published: 2007

Harnessing Solar Energy for Health Needs

Many health facilities in remote areas operate without grid electricity, have unreliable electricity, or find that using electricity is too costly. In these settings, solar energy is a promising solution for powering the storage and transportation …

Author: PATH, World Health Organization

Published: 2012

Helping PEPFAR Partners Manage Health Care Waste: Practical Approaches and Lessons Learned From Uganda and Nigeria

This paper describes the process, tools, and strategies used in the Making Medical Injections Safer project to successfully engage the US President's Emergency Plan for AIDS Relief (PEPFAR) implementing partners in Uganda and Nigeria to improve …

Author: PATH, John Snow Inc.

Published: 2009

Hope for Less Than 50 Cents a Dose: A Revolutionary Model for Developing Low-Cost Vaccines

This fact sheet describes the model employed by the Meningitis Vaccine Project to develop a safe, affordable, and long-lasting vaccine to combat Group A meningococcal epidemics in Africa, as well as the contributions of the key partners who made the …

Author: PATH

Published: 2011

HPV Vaccination in Africa: Lessons Learned From a Pilot Program in Uganda

This report summarizes a human papillomavirus (HPV) vaccination program implemented in Uganda where the HPV vaccine was made available to almost 10,000 girls in select parts of the country. The purpose of the study was to investigate operational …

Author: PATH, Child Health and Development Centre, Uganda National Expanded Program on Immunization

Published: 2011

Human Papillomavirus Vaccine Delivery Strategies That Achieved High Coverage in Low- and Middle-Income Countries

This article, published in the Bulletin of the World Health Organization, documents human papillomavirus (HPV) vaccination coverage after the demonstration projects conducted in India, Peru, Uganda, and Vietnam by PATH and national governments. …

Author: LaMontagne DS, Barge S, Nga TL, et al.

Published: 2011

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