Total results with these characteristics: 198
- Efficacy of Pentavalent Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Infants in Developing Countries in Sub-Saharan Africa: A Randomised, Double-Blind, Placebo-Controlled Trial
This article, published in The Lancet, shares results of an efficacy study of the pentavalent, live oral rotavirus vaccine in Ghana, Kenya, and Mali. Results showed 39.3 percent efficacy against severe rotavirus gastroenteritis. The authors …
Author: Armah GE, Sow SO, Breiman RF, et al.
- Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age
This study, published in the New England Journal of Medicine, evaluated the efficacy of the RTS,S malaria vaccine given with a more immunogenic adjuvant system (AS01E) than one used in a previous study (AS02A). The study was conducted in …
Author: Bejon P, Lusingu J, Olotu A, et al.
- Eliminating Epidemic Group A Meningococcal Meningitis in Africa Through a New Vaccine
This article, published in Health Affairs, discusses a new affordable vaccine against Group A meningococcus, the most common cause of large and often fatal African epidemics of meningitis, that was introduced in Burkina Faso, Mali, and Niger in …
Author: LaForce FM, Okwo-Bele J-M
- Elimination of Haemophilus influenzae type b (Hib) Disease From The Gambia After the Introduction of Routine Immunisation With a Hib Conjugate Vaccine: A Prospective Study
Routine immunization of infants in The Gambia with a Haemophilus influenzae type b (Hib) polysaccharide-tetanus toxoid conjugate vaccine began in May 1997. This article, published in The Lancet, reports on a study that investigated the effectiveness …
Author: Adegbola RA, Secka O, Lahai G, et al.
- Emergence of Serogroup X Meningococcal Disease in Africa: Need for a Vaccine
This article, published in Vaccine, describes how and why serogroup X meningococcal disease has emerged in Africa in recent years. It asserts that while no licensed vaccine is available against serogroup X meningococci, following the introduction of …
Author: Xie O, Pollard AJ, Mueller JE, Norheim G
- Emergency or Routine Vaccination Against Meningococcal Disease in Africa?
This comment, published in The Lancet, is based on a review of the study "Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa." The author concludes that …
Author: Peltola H
- Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa
This article, published in The Lancet, assessed the potential effects of different vaccination strategies against meningococcal disease using data from the 1997 meningococcal outbreak in northern Ghana. Using a simple mathematical model, …
Author: Woods CW, Armstrong G, Sackey SO, et al.
- Enterotoxigenic Escherichia coli in Developing Countries: Epidemiology, Microbiology, Clinical Features, Treatment, and Prevention
This article was published in Clinical Microbiology Reviews. ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial …
Author: Qadri F, Svennerholm AM, Faruque AS, Sack RB
- Environmental Risk and Meningitis Epidemics in Africa
This study, published in Emerging Infectious Diseases, provides evidence that the relationship between the environment and the location of meningitis epidemics is quantifiable. The study proposes a model based on environmental …
Author: Molesworth AM, Cuevas LF, Connor SJ, Morse AP, Thomson MC
- Epidemic Meningitis Due to Group A Neisseria Meningitidis in the African Meningitis Belt: A Persistent Problem With an Imminent Solution
This article, published in the journal Vaccine, emphasizes Group A Neisseria meningitidis as a health problem in Africa and disccuses the potential for a proactive control strategy for epidemic meningitis with the use of …
Author: LaForce FM, Ravenscroft N, Djingarey M, et al
- Epidemiology, Aetiology and Management of Childhood Acute Community-Acquired Pneumonia in Developing Countries--A Review
This article, published in the African Journal of Medicine and Medical Sciences, provides an overview of the causes of clinical pneumonia in developing countries, available vaccines for fighting pneumonia, and efforts underway and planned to expand …
Author: Falade AG, Ayede AI
- Epidemiology of Bacterial Meningitis in Niamey, Niger, 1981-96
This study, published in the Bulletin of the World Health Organization, used retrospective surveillance to identify cases of laboratory-diagnosed bacterial meningitis in Niamey, Niger, from 1981 to 1996. The study analyzed the cases …
Author: Campagne G, Schuchat A, Djibo S, et al.
- The Epidemiology of Human Rotavirus Associated with Diarrhoea in Kenyan Children: A Review
This review of 30 years worth of published data provided insight into the burden of disease and the emergence of new genotypes in Kenya, indicating a need for continued surveillance. ABSTRACT ONLY. (Learn how users in developing countries can …
Author: Kiulia NM, Kamenwa R, Irimu G, et al.
- Evaluating HPV Vaccination Pilots: Practical Experience From PATH
From 2006 to 2011, PATH conducted human papillomavirus (HPV) vaccination demonstration projects in India, Peru, Uganda, and Vietnam to provide evidence for decision-making about public-sector introduction of HPV vaccines. This report provides …
- Evaluation of Cost-Effectiveness of Live Oral Pentavalent Reassortant Rotavirus Vaccine Introduction in Ghana
This article, published in Vaccine, estimates the cost-effectiveness of introducing the rotavirus vaccine RotaTeq® in Ghana. The authors estimated the average costs of treating children with diarrhea in the Ashanti region of Ghana as inpatients …
Author: Abbott C, Tiede B, Armah G, Mahmoud A
- Evaluation of Meningitis Surveillance Before Introduction of Serogroup A Meningococcal Conjugate Vaccine—Burkina Faso and Mali
Before the 2010 to 2011 introduction of the first serogroup A meningococcal conjugate vaccine developed solely for Africa (MenAfriVac), evaluations of the existing meningitis surveillance in Burkina Faso and Mali were conducted to assess the …
Author: US Centers for Disease Control and Prevention
- Evaluation of Serogroup A Meningococcal Vaccines in Africa: A Demonstration Project
This article, published in The Journal of Health, Population, and Nutrition, summarizes the general steps required for meningococcal vaccine development, reviews the use of immunogenicity criteria as a licensing strategy for new meningococcal …
Author: Soriano-Gabarró M, Rosenstein N, LaForce FM
- Evaluation of the Meningitis Epidemics Risk Model in Africa
This study, published in Epidemiology and Infection, evaluated an ecological model based on absolute humidity and land cover type to predict the location of meningitis epidemics in the Sahelian region known as the African Meningitis Belt. The …
Author: Savory EC, Cuevas LE, Yassin MA, et al.
- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
A malaria vaccine, deployed in combination with current malaria-control tools, could play an important role in future control and eventual elimination of malaria in Africa. This article, published in the New England Journal of Medicine (NEJM), …
Author: The RTS,S Clinical Trials Partnership
- Fragile Lives - Immunization at Risk
Hailed as "the greatest public health success story of all time," today childhood immunization faces obstacles never seen before. While immunization still saves three million young lives each year, millions more could be saved if there were enough …
Author: PATH, Barraclough Productions
- From Genomics to Surveillance, Prevention and Control: New Challenges for the African Meningitis Belt
This article, published in the Bulletin de la Société de Pathologie Exotique, summarizes an international conference held in Niamey, Niger, that brought together more than 100 delegates to assess the current meningitis situation in Africa, …
Author: Alonso JM, Bertherat E, Perea W, et al.
- Gambia Pneumococcal Vaccine Trial
This web page offers details of an important vaccine field efficacy study in Africa.
Author: US National Institute of Allergy and Infectious Diseases (NIAID)
- Green Supply Chains: A Glimpse Into the Future?
This project Optimize evidence brief discusses the rationale for introducing net-zero energy systems into vaccine supply chains and describes the experiences and lessons learned in a demonstration project in Tunisia. Opportunities and challenges are …
Author: PATH, World Health Organization
- Haemophilus influenzae type b Conjugate Vaccine Impact Against Purulent Meningitis in Rwanda
Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. This study reviewed …
Author: Muganga N, Uwimana J, Fidele N, et al.
- Harnessing Solar Energy for Health Needs
Many health facilities in remote areas operate without grid electricity, have unreliable electricity, or find that using electricity is too costly. In these settings, solar energy is a promising solution for powering the storage and transportation …
Author: PATH, World Health Organization