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Disease: Shigellosis and enterotoxigenic Escherichia coli (ETEC)

Total results with these characteristics: 73

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Pneumonia and Diarrhoea: Tackling the Deadliest Diseases for the World’s Poorest Children

This report focuses on the huge potential to narrow the child survival gap between the richest and the poorest by focusing on pneumonia and diarrhea—the two primary killers of children under the age of five. It includes a review of the current …

Author: United Nations Children's Fund

Published: 2012

Policymakers Views Regarding the Introduction of New-Generation Vaccines Against Typhoid Fever, Shigellosis, and Cholera in Asia

Published in Vaccine, this article disusses face-to-face interviews and meetings with more than 160 policymakers and other influential professionals in seven large Asian countries (Bangladesh, China, India, Indonesia, Pakistan, Thailand and …

Author: DeRoeck D, Clemens JD, Nyamete A, Mahoney RT

Published: 2005

Prevalance of Enterotoxigenic Escherichia coli-Associated Diarrhea and Carrier State in the Developing World

Published in The Journal of Health, Population, and Nutrition, this study assesses the importance of enterotoxigenic Escherichia coli (ETEC) as a diarrhoeal agent in developing countries.

Author: Wenneras C, Erling V

Published: 2004

Progress and Hurdles in the Development of Vaccines Against Enterotoxigenic Escherichia coli in Humans

This article, published in the Expert Review of Vaccines, describes the status of vaccines under development to address enterotoxigenic Escherichia coli (ETEC), which have been designed to stimulate local intestinal immunity and are delivered either …

Author: Zhang W, Sack DA

Published: 2012

Protecting Aluminum-Adjuvanted Vaccines From Freeze Damage

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global …

Author: PATH

Published: 2012

Protecting Children From Diarrheal Disease: PATH Takes a Comprehensive Approach to Combating This Leading Cause of Child Deaths

This fact sheet provides an overview of PATH's work, including vaccine development and introduction, in protecting children from diarrheal disease.

Author: PATH

Published: 2011

PubMed Searches: ETEC and Shigella

These pre-formatted PubMed searches will retrieve journal citations and available abstracts that address relevant issues related to ETEC and Shigella. Documents may be ordered through Loansome Doc if you have established an agreement with a …

Author: Various

R&D for Diarrhoeal Diseases

While preventive measures such as clean drinking water and sanitation can reduce the risk of infection from diarrheal diseases, research and development (R&D) of new tools is equally important, particularly for vaccines as they can prevent …

Author: Policy Cures

Published: 2013

Reaching a Consensus on Management Practices and Vaccine Development Targets for Mitigation of Infectious Diarrhoea Among Deployed US Military Forces

Published in the Journal of Evalution in Clinical Practice, this study was part of a research effort to identify and quantify factors related to the cost-effectiveness of a vaccine acquisition strategy to reduce the burden of infectious diarrhea on …

Author: Riddle MS, Tribble DR

Published: 2008

Reactive Arthritis Following Culture-Confirmed Infections with Bacterial Enteric Pathogens in Minnesota and Oregon: A Population-based Study

This article, published in Annals of the Rheumatic Diseases, describes the epidemiology and clinical spectrum of reactive arthritis (ReA) following culture-confirmed infection with bacterial enteric pathogens in a population-based study in …

Author: Townes JM, Deodhar AA, Laine ES, et al.

Published: 2008

Recent Progress Towards Development of a Shigella Vaccine

The burden of dysentery due to shigellosis among children in the developing world is a major concern, but no licensed vaccine is available. This review article, published in Expert Review of Vaccines, provides an update on Shigella vaccine …

Author: Camacho AI, Irache JM, Gamazo C

Published: 2013

Refinement of a Human Challenge Model for Evaluation of Enterotoxigenic Escherichia coli Vaccines

This article, published in Clinical and Vaccine Immunology, reports on a study which found that a lower dose than used previously of the human challenge model for enterotoxigenic Escherichia coli diarrhea using strain H10407 is sufficient for …

Author: Harro C, Chakraborty S, Feller A, et al.

Published: 2011

A Review of Vaccine Research and Development: Human Enteric Infections

Published in the journal Vaccine, the article reviews the state of the art in vaccine research and development against human viral and bacterial enteric infections of public health importance.

Author: Girard MP, Steele D, Chaignat CL, Kieny MP

Published: 2006

Safety and Immunogenicity of a Single Oral Dose of Recombinant Double-Mutant Heat-Labile Toxin (dmLT) Derived from Enterotoxigenic Escherichia coli (ETEC)

This article, published in Clinical and Vaccine Immunology, reports on a Phase 1 clinical trial which determined the safety and immunogenicity of a recombinantly produced dmLT of ETEC. Study results showed that a single oral dose of dmLT was well …

Author: El-Kamary SS, Cohen MB, Bourgeois AL, et al.

Published: 2013

Setting Research Priorities to Reduce Global Mortality From Childhood Diarrhea by 2015

To assist donors in understanding the potential of different research avenues to contribute to reducing the burden of disease and disability, the Child Health and Nutrition Research Initiative (CHNRI) of the Global Forum for Health Research recently …

Author: Fontaine O, Kosek M, Bhatnagar S, et al.

Published: 2009

Shigella

This web page provides general information on Shigella bacteria, symptoms of disease, and treatment options. It also includes links to other World Health Organization web pages related to Shigella.

Author: World Health Organization

State of the Art of New Vaccines: Research and Development

This document analyzes research and development activities for vaccines against infectious diseases of public health importance. Disease groups covered include diarrheal disease, sexually transmitted diseases, respiratory infections, bacterial …

Author: World Health Organization

Published: 2006

Summary of Vaccine Stability Data

These documents provide stability data as of November 2012 on commonly used, licensed vaccines and stability data as of May 2012 from available data on novel, investigational vaccine formulations. Data are sorted by vaccine in a table format in both …

Author: PATH, Working in Tandem Ltd.

Published: 2012

Vaccination Against Enterotoxigenic Escherichia coli, A Cause of Travelers' Diarrhea

This review, published in The Journal of Travel Medicine, focuses on the strategies behind development and potential use of currently available vaccines and vaccine candidates against enterotoxigenic Escherichia coli (ETEC) infection. As …

Author: Steffen R, Castelli F, Dieter Nothdurft H, Rombo L, Jane Zuckerman N

Published: 2005

Vaccine Development Global Program

This website provides information about the work of PATH’s Vaccine Development Global Program to improve the health of people, especially infants and children living in low-income countries, by accelerating the development of vaccines …

Author: PATH

Vaccines for Enteric Diseases: A Meeting Summary

This article, published in Expert Review of Vaccines, summarizes the presentations and outcomes from the 6th Vaccines for Enteric Diseases Symposium held in Cannes, France, on 14 to 16 September 2011, which drew approximately 200 vaccine developers, …

Author: Steele D, Riddle M, van de Verg L, Bourgeois L

Published: 2012

Vaccines for the Future

This quarterly e-newsletter provides an update on PATH’s efforts to accelerate the development of innovative, safe, effective, and affordable vaccines against the leading causes of childhood deaths in developing-world populations, pneumonia …

Author: PATH

Vaccines in Fast-Dissolving Tablets: Novel Product Format to Ensure Vaccine Effectiveness, Affordability, and Ease of Use

This fact sheet provides an overview of PATH's work in developing fast-dissolving tablet vaccine formulations that are manufactured using a standard lyophilization process. The small tablets are packaged in unit-dose blisters offering an …

Author: PATH

Published: 2012

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