Resource type: Peer-reviewed journal
Total results with these characteristics: 620
- Assessing the Potency of Oral Polio Vaccine Kept Outside of the Cold Chain During a National Immunization Campaign in Chad
This article, published in Vaccine, reports on a study of the potency of monovalent oral polio vaccine type 3 kept at ambient temperatures during a polio immunization campaign in Chad. The results of the study show that post-campaign laboratory …
Author: Zipursky S, Boualam L, Cheikh DO, et al.
- Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo-Controlled, Randomized Double-Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine
This article, published in PLOS ONE, reports on the results of a double-blinded, randomized, placebo-controlled Phase 1 clinical trial of a cold-adapted and temperature-sensitive A/H7N3 live attenuated influenza vaccine candidate. The results of the …
Author: Rudenko L, Kiseleva I, Naykhin AN, et al.
- Association Between Pentavalent Rotavirus Vaccine and Severe Rotavirus Diarrhea Among Children in Nicaragua
This article, published in the Journal of the American Medical Association, summarizes the first study to assess the impact of rotavirus vaccination in a developing country. The authors concluded that the vaccine could have a substantial impact on …
Author: Patel M, Pedreira C, De Oliveira LH, et al.
- Avian and Pandemic Influenza: An Overview
This brief overview, published in the journal Vaccine, reviews basic virologic, immunologic, and epidemiologic information relevant to understanding and preparing for a pandemic influenza threat. In particular, the role of avian influenza …
Author: Poland G, Jacobson R, Targonski P
- Bacterial Diarrhea
This article, published in the New England Journal of Medicine, provides a description of bacterial diarrhea and evidence supporting various strategies to combat this problem. Also included are a list of pathogens that cause bacterial diarrhea and …
Author: DuPont HL
- Bacterial Pneumonia Vaccines and Childhood Pneumonia: Are We Winning, Refining, or Redefining?
Published in The Lancet Infectious Diseases, this article provides an overview of the diagnostic challenges of bacterial pneumonia and highlight the need for refining the current diagnostic approach to ensure adequate epidemiological surveillance of …
Author: Obaro S, Madhi S
- Baseline Meningococcal Carriage in Burkina Faso Before the Introduction of a Meningococcal Serogroup A Conjugate Vaccine
The vaccine MenAfriVac™ has the potential to confer herd immunity by reducing carriage prevalence of epidemic strains. To better understand this phenomenon, the authors of this article, published in Clinical and Vaccine …
Author: Kristiansen PA, Diomandé F, Wei SC, et al.
- Best Infection Control Practices for Interdermal, Subcutaneous, and Intramuscular Needle Injections
From the Bulletin of the World Health Organization, this article discusses evidence-based guidelines for making injections safer. Abstracts are available in Spanish, French, and Arabic.
Author: Hutin Y, Hauri A, Chiarello L, et al.
- Biological Challenges and Technological Opportunities for Respiratory Syncytial Virus Vaccine Development
This article, published in Immunological Reviews, provides an overview of the barriers that have challenged and delayed the development of vaccines against respiratory syncytial virus (RSV) and identifies opportunities that could help overcome these …
Author: Graham B
- Broadening the Age Restriction for Initiating Rotavirus Vaccination in Regions With High Rotavirus Mortality: Benefits of Mortality Reduction Versus Risk of Fatal Intussusception
This article, published in Vaccine, reports on a study that assessed the potential benefits of mortality reduction versus the risk of fatal intussusception when (a) the first dose of rotavirus vaccine was administered by 12 weeks of age compared …
Author: Patel MM, Clark AD, Glass RI, et al.
- Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein
Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …
Author: Mann B, Thornton J, Heath R, et al.
- A Broken Trust: Lessons from the Vaccine–Autism Wars
This article, published in PLoS Biology, discusses Sharon Kaufman's investigation into the forces fueling the growing divide between scientists and citizens, with the vaccine–autism link as her example. Kaufman aimed to …
Author: Gross L
- Burden and Aetiology of Diarrhoeal Disease in Infants and Young Children in Developing Countries (the Global Enteric Multicenter Study, GEMS): A Prospective, Case-Control Study
This article, published in The Lancet, reports on results of the Global Enteric Multicenter Study (GEMS), which was designed to identify the aetiology and population-based burden of pediatric diarrheal disease in sub-Saharan Africa and south Asia. …
Author: Kotloff KL, Nataro JP, Blackwelder WC, et al.
- Burden of Disease and Circulating Serotypes of Rotavirus Infection in Sub-Saharan Africa: Systematic Review and Meta-analysis
To assess the potential impact of rotavirus vaccines in sub-Saharan Africa, researchers reviewed recent published data on rotavirus burden among children aged five years old and circulating serotypes in sub-Saharan Africa. Though many countries …
Author: Sanchez-Padilla E, Grais RF, Guerin PJ, et al.
- Burden of Disease Caused by Streptococcus Pneumoniae in Children Younger than 5 Years: Global Estimates
This article, published in The Lancet, releases new global burden of disease data for Streptococcus pneumoniae (pneumococcus), a leading cause of bacterial pneumonia, meningitis, and sepsis in children worldwide. The results also include data at the …
Author: O'Brien KL, Wolfson LJ, Watt JP, et al.
- Burden of Paediatric Rotavirus Gastroenteritis (RVGE) and Potential Benefits of a Universal Rotavirus Vaccination Programme with a Pentavalent Vaccine in Spain
This study, published in BMC Public Health, assesses the health outcomes and the economic impact of a universal rotavirus vaccination program with RotaTeq, a pentavalent rotavirus vaccine, against a no vaccination program in Spain. The study …
Author: Diez-Domingo J, Surinach NL, Alcalde NM, Betegon L, Largeron N, Trichard M
- The Burden of Pneumococcal Disease Among Latin American and Caribbean Children: Review of the Evidence
This article, published in the Pan American Journal of Public Health, estimates the annual burden of pneumonia, meningitis, and acute otitis media caused by pneumococcus in children less than five years of age in Latin America and the …
Author: Valenzuela MT, O'Loughlin R, De La Hoz F, et al.
- A Call to Action for the New Decade of Vaccines
This article, published in The Lancet, argues that there is a moral imperative to make vaccines widely available on an equitable basis. The authors lay out a call to action for the new decade of vaccines, which embraces four key elements. …
Author: Moxon ER, Das P, Greenwood B, et al.
- Can Successful Vaccines Teach Us How to Induce Efficient Protective Immune Responses?
This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …
Author: Lambert PH, Liu M, Siegrist CA
- Can We Defeat Meningococcal Disease in Low and Middle Income Countries?
This article, published in Vaccine, discusses the challenges of achieving control of meningococcal disease in low- and middle-income countries. The authors argue that in low-income countries the main challenge is a lack of sufficient epidemiological …
Author: Greenwood B, Chiarot E, MacLennan CA, O'Ryan M
- Can We, Should We, Eradicate the Meningococcus?
The authors of this article, published in Vaccine, discuss how the introduction of vaccines against Neisseria meningitidis raises the question of whether disease caused by this obligate human bacterium can be controlled, eliminated, or even …
Author: Maiden MC, Frosch M
- Cervical Cancer Prevention and the Millennium Development Goals
This article, published in the Bulletin of the World Health Organization, explores how scaled-up cervical cancer prevention activities, including introduction of the new HPV vaccines and increased access to precancer screening and treatment, can …
Author: Wittet S, Tsu V
- Challenges Faced by the Global Polio Eradication Initiative
After the World Health Assembly resolved in 1988 to eradicate wild poliovirus (WPV) transmission globally by 2000, dramatic progress in reducing polio cases and increasing the number of countries that interrupted indigenous WPV transmission was …
Author: Wassilak S, Orenstein W
- Challenges in Developing a Pediatric RSV Vaccine
There is currently no approved respiratory syncytial virus (RSV) vaccine, and the goal of preventing RSV-associated illness in the general population remains unmet. The authors of this article, published in Human Vaccines, discuss the challenges …
Author: Schickli JH, Dubovsky F, Tang RS
- Changes in Hospitalisations for Acute Gastroenteritis in Australia After the National Rotavirus Vaccination Program
This retrospective analysis, published in the Medical Journal of Australia, found a sustained and substantial decline in rotavirus hospitalizations as well as hospitalizations for diarrhea of any cause following national vaccine …
Author: Dey A, Wang H, Menzies R, Macartney K