Topic: Vaccine stabilization
Total results with these characteristics: 34
- Stabilization of Vaccines: Lessons Learned
This editorial, published in Human Vaccines, explores the key logistical, regulatory, procurement, and policy issues associated with the development and use of temperature-stabilized vaccines. The authors reflect on nearly 8 years of work to …
Author: Kristensen D, Chen D
- Summary of Vaccine Stability Data
These documents provide the latest stability data for commonly used vaccines and current research on vaccine formulations and platform technologies. Data are sorted by vaccine in a table format in both documents.
Author: PATH, Working in Tandem Ltd.
- Temperature Sensitivity of Vaccines
This document addresses issues regarding potential exposure of temperature-sensitive vaccines to freezing temperatures and provides updated information on vaccine vial monitors, as well as a discussion of future advances in cold chain technology.
Author: World Health Organization
- Thermostable Formulations of a Hepatitis B Vaccine and a Meningitis A Polysaccharide Conjugate Vaccine Produced by a Spray-Drying Method
This article, published in the journal Vaccine, reports that employing a spray-drying process to produce glassy state formulations of two common subunit vaccines demonstrates that the production of thermostable vaccines is achievable. The process …
Author: Chen D, Kapre S, Goel A, et al.
- Vaccine Stabilization
This fact sheet describes PATH's work on vaccine stabilization, including the development of a method to protect vaccines containing an aluminum adjuvant from freeze damage, the identification of a technology to improve the heat stability of certain …
- Vaccine Stabilization: Research, Commercialization, and Potential Impact
This article, published in Vaccine, discusses the challenges of different approaches to developing and producing thermostable vaccines. Topics include the technical feasibility of improving vaccine thermostability and thus vaccine effectiveness …
Author: Kristensen D, Chen D, Cummings R
- Vaccine Technologies at PATH
PATH and its partners have been advancing innovative vaccine technologies for more than 30 years. This report outlines PATH's approach and capabilities. It also describes a number of individual vaccine technologies at various …
- Vaccines in Fast-Dissolving Tablets: Novel Product Format to Ensure Vaccine Effectiveness, Affordability, and Ease of Use
This fact sheet provides an overview of PATH's work in developing fast-dissolving tablet vaccine formulations that are manufactured using a standard lyophilization process. The small tablets are packaged in unit-dose blisters offering an …
- Vaccines With Aluminum-Containing Adjuvants: Optimizing Vaccine Efficacy and Thermal Stability
Aluminum-containing adjuvants have been in use in vaccines for decades to enhance immune responses. However, exposure of vaccines containing these adjuvants to temperatures outside of the recommended storage ranges (especially exposure to freezing …
Author: Clapp T, Siebert P, Chen D, Jones Braun L