Topic: Disease/vaccine specific information
Total results with these characteristics: 958
- Analysis of Strategies to Successfully Vaccinate Infants in Developing Countries Against Enterotoxigenic E. coli (ETEC) Disease
This article, published in Vaccine, outlines current candidates for a safe and effective vaccine against ETEC. The authors argue that a critical roadblock to achieving this goal has not been the science as much as the lack of a sufficiently funded …
Author: Walker RI, Steele D, Aguado T, Ad Hoc ETEC Technical Expert Committee
- Analysis of World Health Organization Policy Development Processes for a New Intervention: Malaria Vaccines
This document aims to elucidate the World Health Organization (WHO) process for developing policy guidelines for a malaria vaccine. The analysis considered past WHO recommendations on new interventions and assessed potential implications …
- Andhra Pradesh: Building a Model Immunization System
This report discusses the work of PATH's Children's Vaccine Program and the Indian state of Andhra Pradesh to build a model immunization program, including the incorporation of hepatitis B vaccine into the childhood vaccination program.
- Antibody-Independent, Interleukin-17A-Mediated, Cross-serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide
Published in the journal Infection and Immunity, this article shows that C-Ps given intranasally with mucosal adjuvant increased the resistance of mice to experimental nasopharyngeal colonization by capsulated S. pneumoniae of serotype 6B.
Author: Malley R, Srivastava A, Lipsitch M, et al.
- Apical Membrane Antigen 1: A Malaria Vaccine Candidate in Review
This article, published in Trends in Parasitology, presents the current understanding of apical membrane antigen 1 (AMA1), particularly in relation to the potential of AMA1 as a malaria vaccine and the approaches being taken toward clinical …
Author: Remarque EJ, Faber BW, Kocken CH, Thomas AW
- An Approach to Formative Research in HPV Vaccine Introduction Planning in Low-Resource Settings
Formative research can inform country-level vaccine delivery strategies, communication messages, and advocacy plans. This article, published in The Open Vaccine Journal, describes the conceptual framework of the formative research conducted by …
Author: Bingham A, Janmohamed A, Bartolini R, et al.
- Architecture of Respiratory Syncytial Virus Revealed by Electron Cryotomography
This article, published in the Proceedings of the National Academy of Sciences of the United States of America, describes research to carry out an electron cryotomographic characterization of cell culture-grown human respiratory syncytial virus to …
Author: Liljeroos L, Krzyzaniak MA, Helenius A, Butcher SJ
- Artemisinin Resistance in Plasmodium falciparum Malaria
This study, published in the New England Journal of Medicine, compares the efficacies of two treatments--oral artesunate and artesunate followed by mefloquine--for uncomplicated falciparum malaria in Pailin, western Cambodia, and Wang Pha, …
Author: Dondorp AM, Nosten F, Yi P, et al.
- Ask the Experts: Update on the Safety of Rotavirus Vaccines
This article, published by the American Pharmacists Association, addresses the safety of rotavirus vaccines, including the latest information on possible contamination issues. The authors indicate that the documented benefits of RotaTeq and …
Author: Mojica B, Hess K
- Assessing Disease Burden of JE: Population-Based Surveillance
This slide presentation provides an overview of the components of a population-based surveillance system for JE. The presentation should be used in conjunction with the World Health Organization's Recommended Standards for Surveillance of Selected …
- Assessing Efficacy of Haemophilus influenzae type b Combination Vaccines
Regulatory approval of diphtheria and tetanus toxoids and acellular pertussis (DTaP)-based combination vaccines containing Haemophilus influenzae type b (Hib) has been delayed in the United States because of difficulty in assessing the effect of …
Author: Granoff DM
- Assessing the Environment for Introduction of Human Papillomavirus Vaccine in India
This article, published in The Open Vaccine Journal, presents findings from a study conducted in 2007 and 2008 in two states in India: Andhra Pradesh and Gujarat. The objectives of the study were to: design effective and appropriate HPV vaccine …
Author: Jacob M, Mawar N, Menezes L, et al.
- Assessing the Potency of Oral Polio Vaccine Kept Outside of the Cold Chain During a National Immunization Campaign in Chad
This article, published in Vaccine, reports on a study of the potency of monovalent oral polio vaccine type 3 kept at ambient temperatures during a polio immunization campaign in Chad. The results of the study show that post-campaign laboratory …
Author: Zipursky S, Boualam L, Cheikh DO, et al.
- Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo-Controlled, Randomized Double-Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine
This article, published in PLOS ONE, reports on the results of a double-blinded, randomized, placebo-controlled Phase 1 clinical trial of a cold-adapted and temperature-sensitive A/H7N3 live attenuated influenza vaccine candidate. The results of the …
Author: Rudenko L, Kiseleva I, Naykhin AN, et al.
- Association Between Pentavalent Rotavirus Vaccine and Severe Rotavirus Diarrhea Among Children in Nicaragua
This article, published in the Journal of the American Medical Association, summarizes the first study to assess the impact of rotavirus vaccination in a developing country. The authors concluded that the vaccine could have a substantial impact on …
Author: Patel M, Pedreira C, De Oliveira LH, et al.
- Avian and Pandemic Influenza: An Overview
This brief overview, published in the journal Vaccine, reviews basic virologic, immunologic, and epidemiologic information relevant to understanding and preparing for a pandemic influenza threat. In particular, the role of avian influenza …
Author: Poland G, Jacobson R, Targonski P
- Avian Influenza (Bird Flu)
This web page provides important information for the public, health professionals, and travelers on avian influenza, including key facts on how the virus is spread and treatment for avian influenza.
Author: US Centers for Disease Control and Prevention
- Bacterial Diarrhea
This article, published in the New England Journal of Medicine, provides a description of bacterial diarrhea and evidence supporting various strategies to combat this problem. Also included are a list of pathogens that cause bacterial diarrhea and …
Author: DuPont HL
- Bacterial Pneumonia Vaccines and Childhood Pneumonia: Are We Winning, Refining, or Redefining?
Published in The Lancet Infectious Diseases, this article provides an overview of the diagnostic challenges of bacterial pneumonia and highlight the need for refining the current diagnostic approach to ensure adequate epidemiological surveillance of …
Author: Obaro S, Madhi S
- Biological Challenges and Technological Opportunities for Respiratory Syncytial Virus Vaccine Development
This article, published in Immunological Reviews, provides an overview of the barriers that have challenged and delayed the development of vaccines against respiratory syncytial virus (RSV) and identifies opportunities that could help overcome these …
Author: Graham B
- Breakeven Analysis for Various Human Papillomavirus Vaccine Presentations in Vietnam and Uganda
This report highlights a study that uses a breakeven cost analysis to compare potential prices, wastage rates, and cold chain requirements for various human papillomavirus vaccine presentations. The results of this study provide insight into …
Author: PATH, World Health Organization
- Breaking the Cycle With Vaccines: The Malaria Life Cycle
This graphic displays the malaria parasite's life cycle and highlights where three different types of vaccines could interrupt various stages of the life cycle.
- Broadening the Age Restriction for Initiating Rotavirus Vaccination in Regions With High Rotavirus Mortality: Benefits of Mortality Reduction Versus Risk of Fatal Intussusception
This article, published in Vaccine, reports on a study that assessed the potential benefits of mortality reduction versus the risk of fatal intussusception when (a) the first dose of rotavirus vaccine was administered by 12 weeks of age compared …
Author: Patel MM, Clark AD, Glass RI, et al.
- Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein
Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …
Author: Mann B, Thornton J, Heath R, et al.
- Burden and Aetiology of Diarrhoeal Disease in Infants and Young Children in Developing Countries (the Global Enteric Multicenter Study, GEMS): A Prospective, Case-Control Study
This article, published in The Lancet, reports on results of the Global Enteric Multicenter Study (GEMS), which was designed to identify the aetiology and population-based burden of pediatric diarrheal disease in sub-Saharan Africa and south Asia. …
Author: Kotloff KL, Nataro JP, Blackwelder WC, et al.