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Topic: Vaccine safety and performance

Total results with these characteristics: 214

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Concomitant Administration of Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) and Measles, Mumps, Rubella (MMR) Vaccine: Randomized Study in Toddlers in Taiwan

This article, published in Vaccine, reports on a study that examined the safety and efficacy of administering Japanese encephalitis vaccine (JE-CV) and measles, mumps, rubella (MMR) vaccine six weeks apart or concomitantly in children aged 12 to 18 …

Author: Huang L-M, Lin T-Y, Chiu C-H, et al.

Published: 2014

Continuing Increases in Autism Reported to California's Developmental Services System

This study, published in the journal Archives of General Psychiatry, evaluates the rates of autism in California following the discontinued use of thimerosal in childhood vaccines. ABSTRACT ONLY. (Learn how users in developing countries …

Author: Schechter R, Grether J

Published: 2008

Cotton Rats Previously Immunized With a Chimeric RSV FG Glycoprotein Develop Enhanced Pulmonary Pathology When Infected With RSV, a Phenomenon not Encountered Following Immunization With Vaccinia-RSV Recombinants or RSV

In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …

Author: Connors M, Collins PL, Firestone CY, et al.

Published: 1992

Current Knowledge Regarding the Investigational 13-valent Pneumococcal Conjugate Vaccine

This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …

Author: Dinleyici EC, Yargic ZA

Published: 2009

Decade of Vaccines

This supplement to Vaccine features articles on the Decade of Vaccines Global Vaccine Action Plan strategic objectives and the opportunities and challenges associated with its implementation. The 27 articles in the supplement cover a range of …

Author: Alonso PL, de Quadros CA, Lal AA, eds.

Published: 2013

Decline in Severe Diarrhea Hospitalizations After the Introduction of Rotavirus Vaccination in Ghana: A Prevalence Study

This article, published in BMC Infectious Diseases, reports on the results of a study that examined diarrheal hospitalizations of children aged 59 months and younger before and after the introduction of rotavirus vaccination in Ghana. The results …

Author: Enweronu-Laryea CC, Boamah I, Sifah E, Diamenu SK, Armah G

Published: 2014

Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant

This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …

Author: Holmgren J, Bourgeois L, Carlin N, et al.

Published: 2013

Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries

This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …

Author: Heidt PJ, Walker RI, Rusch V, eds.

Published: 2011

Diarrhoea-Related Hospitalizations in Children Before and After Implementation of Monovalent Rotavirus Vaccination in Mexico

This article, published in the Bulletin of the World Health Organization, reports on a study that compared the incidence of diarrhea in young children before and after the national introduction of monovalent rotavirus vaccine in Mexico. The results …

Author: Esparza-Aguilar M, Gastañaduy PA, Sánchez-Uribe E, et al.

Published: 2014

A Dose-Escalation Safety and Immunogenicity Study of Live Attenuated Oral Rotavirus Vaccine 116E in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

This study, published in the Journal of Infectious Diseases, tested the neonatal rotavirus candidate vaccine 116E in a double-blind, placebo-controlled dose-escalation trial in India. Two doses of the Vero cell-adapted vaccine were evaluated in …

Author: Bhandari N, Sharma P, Taneja S, et al.

Published: 2009

Early Thimerosal Exposure and Neuropsychological Outcome at 7 and 10 Years

Investigators assessed neurological outcomes by testing more than 1,000 children aged 7 to 10 years and determined that early exposure to mercury from thimerosal-containing vaccines was not associated with deficits in neuropsychological functioning. …

Author: Thompson W, Price C, Goodson B, et al.

Published: 2007

Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

This article, published in The New England Journal of Medicine, discusses a study on the efficacy of rotavirus vaccine in Africa. Results showed 30.2 percent efficacy against all-cause severe gastroenteritis. The study concluded that rotavirus …

Author: Madhi SA, Cunliffe NA, Steele D, et al.

Published: 2010

Effect of Multiple, Simultaneous Vaccines on Polio Seroresponse and Associated Health Outcomes

This article, published in Vaccine, compared vaccination with inactivated polio vaccine (IPV) alone or simultaneously with one other vaccine to vaccination with IPV and four other vaccines among adults in the United States military. The results …

Author: Broderick MP, Oberste MS, Moore D, Romero-Steiner S, Hansen CJ, Faix DJ

Published: 2014

Effect of Single Dose of SA 14-14-2 Vaccine One Year After Immunisation in Nepalese Children with Japanese Encephalitis: A Case-Control Study

Published in The Lancet, investigators conducted a case-control study and efficacy of the SA 14-14-2 JE vaccine to be 98.5 percent 12 to 15 months after vaccination. ABSTRACT ONLY. (Learn how users in developing countries can gain free access …

Author: Ohrr H, Tandan JB, Sohn YM, et al.

Published: 2005

Effectiveness of an Indian-made Attenuated Influenza A(H1N1)pdm 2009 Vaccine: A Case Control Study

This article, published in Human Vaccines & Immunotherapeutics, details a case control study to evaluate the effectiveness of a live attenuated A(H1N1)pdm 2009 vaccine produced by the Serum Institute of India, Ltd., which was distributed in …

Author: Kulkarni PS, Agarkhedkar S, Lalwani S, et al.

Published: 2014

Effectiveness of Meningococcal Serogroup C Vaccine Programmes

Since the introduction of monovalent meningococcal serogroup C (MenC) glycoconjugate (MCC) vaccines and the implementation of national vaccination programs, the incidence of MenC disease has declined markedly as a result of effective short-term …

Author: Borrow R, Abad R, Trotter C, van der Kils FRM, Vazquez JA

Published: 2013

Effectiveness of Monovalent Rotavirus Vaccine in Bolivia: Case-Control Study

This article, published in BMJ, reports on a study that evaluated the effectiveness of two doses of a monovalent rotavirus vaccine against hospital admission for rotavirus at six hospitals in Bolivia, between March 2010 and June 2011. Results show …

Author: Patel MM, Patzi M, Pastor D, et al.

Published: 2013

Effectiveness of Pentavalent and Monovalent Rotavirus Vaccines in Concurrent Use Among US Children <5 Years of Age, 2009–2011

This article, published in Clinical Infectious Diseases, summarizes a study that assessed vaccine effectiveness of RotaTeq (RV5; 3 doses) and Rotarix (RV1; 2 doses) at reducing rotavirus acute gastroenteritis inpatient and emergency department (ED) …

Author: Payne DC, Boom JA, Staat MA, et al.

Published: 2013

Efficacy and Safety of Human Papillomavirus Vaccine for Primary Prevention of Cervical Cancer: A Review of Evidence From Phase III Trials and National Programs

This article, published in the South Asian Journal of Cancer, discusses the justification of human papillomavirus (HPV) vaccination in the backdrop of the natural history of cervical cancer, the mechanism of action of the vaccines, and efficacy and …

Author: Basu P, Banerjee D, Singh P, Bhattacharya C, Biswas J

Published: 2013

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine During 18 Months After Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

This article, published in PLoS Medicine, reports on follow-up data from a Phase 3 trial conducted to test the effectiveness of the malaria vaccine candidate RTS,S/AS01 in children and young infants. RTS,S/AS01 prevented many cases of clinical and …

Author: RTS,S Clinical Trials Partnership

Published: 2014

Efficacy of a Monovalent Human-Bovine (116E) Rotavirus Vaccine in Indian Infants: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, reports on the results of a Phase 3 study to assess the efficacy and tolerability of a monovalent human-bovine rotavirus vaccine (116E) for severe rotavirus gastroenteritis in low-resource urban and rural …

Author: Bhandari N, Rongsen-Chandola T, Bavdekar A, et al.

Published: 2014

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Published: 2007

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Published: 2013

Efficacy, Safety, and Immunogenicity of the Human Papillomavirus 16/18 AS04-Adjuvanted Vaccine in Women Older Than 25 Years: 4-Year Interim Follow-Up of the Phase 3, Double-Blind, Randomised Controlled VIVIANE Study

This article, published in The Lancet, discusses the results of an efficacy, safety, and immunogenicity study of the human papillomavirus (HPV) 16/18 vaccine in adult women. The results showed that in women older than 25 years, the HPV 16/18 vaccine …

Author: Skinner SR, Szarewski A, Romanowski B, et al.

Published: 2014

An Epidemiologic Study of Altered Clinical Reactivity to Respiratory Syncytial (RS) Virus Infection in Children Previously Vaccinated With an Inactivated RS Virus Vaccine

This article, published in the American Journal of Epidemiology, describes a study that evaluated altered clinical reactivity to a formalin-inactivated respiratory syncytial virus (RSV) vaccine candidate administered to healthy infants and children …

Author: Kapikian AZ, Mitchell RH, Chanock RM, Shvedoff RA, Stewart CE

Published: 1969

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