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Topic: Vaccine safety and performance

Total results with these characteristics: 203

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Continuing Increases in Autism Reported to California's Developmental Services System

This study, published in the journal Archives of General Psychiatry, evaluates the rates of autism in California following the discontinued use of thimerosal in childhood vaccines. ABSTRACT ONLY. (Learn how users in developing countries …

Author: Schechter R, Grether J

Published: 2008

Cotton Rats Previously Immunized With a Chimeric RSV FG Glycoprotein Develop Enhanced Pulmonary Pathology When Infected With RSV, a Phenomenon not Encountered Following Immunization With Vaccinia-RSV Recombinants or RSV

In studies conducted in the 1960s, children previously immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine (FI-RSV) developed a greater incidence and severity of pulmonary disease during subsequent natural RSV infection …

Author: Connors M, Collins PL, Firestone CY, et al.

Published: 1992

Current Knowledge Regarding the Investigational 13-valent Pneumococcal Conjugate Vaccine

This article, published in Expert Reviews of Vaccines, explains the latest knowledge about the investigational 13-valent pneumococcal conjugate vaccine (PCV-13). It outlines the composition of the vaccine and the trials it has undergone to date …

Author: Dinleyici EC, Yargic ZA

Published: 2009

Decade of Vaccines

This supplement to Vaccine features articles on the Decade of Vaccines Global Vaccine Action Plan strategic objectives and the opportunities and challenges associated with its implementation. The 27 articles in the supplement cover a range of …

Author: Alonso PL, de Quadros CA, Lal AA, eds.

Published: 2013

Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant

This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …

Author: Holmgren J, Bourgeois L, Carlin N, et al.

Published: 2013

Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries

This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …

Author: Heidt PJ, Walker RI, Rusch V, eds.

Published: 2011

Diarrhoea-Related Hospitalizations in Children Before and After Implementation of Monovalent Rotavirus Vaccination in Mexico

This article, published in the Bulletin of the World Health Organization, reports on a study that compared the incidence of diarrhea in young children before and after the national introduction of monovalent rotavirus vaccine in Mexico. The results …

Author: Esparza-Aguilar M, Gastañaduy PA, Sánchez-Uribe E, et al.

Published: 2014

A Dose-Escalation Safety and Immunogenicity Study of Live Attenuated Oral Rotavirus Vaccine 116E in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

This study, published in the Journal of Infectious Diseases, tested the neonatal rotavirus candidate vaccine 116E in a double-blind, placebo-controlled dose-escalation trial in India. Two doses of the Vero cell-adapted vaccine were evaluated in …

Author: Bhandari N, Sharma P, Taneja S, et al.

Published: 2009

Early Thimerosal Exposure and Neuropsychological Outcome at 7 and 10 Years

Investigators assessed neurological outcomes by testing more than 1,000 children aged 7 to 10 years and determined that early exposure to mercury from thimerosal-containing vaccines was not associated with deficits in neuropsychological functioning. …

Author: Thompson W, Price C, Goodson B, et al.

Published: 2007

Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

This article, published in The New England Journal of Medicine, discusses a study on the efficacy of rotavirus vaccine in Africa. Results showed 30.2 percent efficacy against all-cause severe gastroenteritis. The study concluded that rotavirus …

Author: Madhi SA, Cunliffe NA, Steele D, et al.

Published: 2010

Effect of Single Dose of SA 14-14-2 Vaccine One Year After Immunisation in Nepalese Children with Japanese Encephalitis: A Case-Control Study

Published in The Lancet, investigators conducted a case-control study and efficacy of the SA 14-14-2 JE vaccine to be 98.5 percent 12 to 15 months after vaccination. ABSTRACT ONLY. (Learn how users in developing countries can gain free access …

Author: Ohrr H, Tandan JB, Sohn YM, et al.

Published: 2005

Effectiveness of an Indian-made Attenuated Influenza A(H1N1)pdm 2009 Vaccine: A Case Control Study

This article, published in Human Vaccines & Immunotherapeutics, details a case control study to evaluate the effectiveness of a live attenuated A(H1N1)pdm 2009 vaccine produced by the Serum Institute of India, Ltd., which was distributed in …

Author: Kulkarni PS, Agarkhedkar S, Lalwani S, et al.

Published: 2014

Effectiveness of Meningococcal Serogroup C Vaccine Programmes

Since the introduction of monovalent meningococcal serogroup C (MenC) glycoconjugate (MCC) vaccines and the implementation of national vaccination programs, the incidence of MenC disease has declined markedly as a result of effective short-term …

Author: Borrow R, Abad R, Trotter C, van der Kils FRM, Vazquez JA

Published: 2013

Effectiveness of Monovalent Rotavirus Vaccine in Bolivia: Case-Control Study

This article, published in BMJ, reports on a study that evaluated the effectiveness of two doses of a monovalent rotavirus vaccine against hospital admission for rotavirus at six hospitals in Bolivia, between March 2010 and June 2011. Results show …

Author: Patel MM, Patzi M, Pastor D, et al.

Published: 2013

Effectiveness of Pentavalent and Monovalent Rotavirus Vaccines in Concurrent Use Among US Children <5 Years of Age, 2009–2011

This article, published in Clinical Infectious Diseases, summarizes a study that assessed vaccine effectiveness of RotaTeq (RV5; 3 doses) and Rotarix (RV1; 2 doses) at reducing rotavirus acute gastroenteritis inpatient and emergency department (ED) …

Author: Payne DC, Boom JA, Staat MA, et al.

Published: 2013

Efficacy and Safety of Human Papillomavirus Vaccine for Primary Prevention of Cervical Cancer: A Review of Evidence From Phase III Trials and National Programs

This article, published in the South Asian Journal of Cancer, discusses the justification of human papillomavirus (HPV) vaccination in the backdrop of the natural history of cervical cancer, the mechanism of action of the vaccines, and efficacy and …

Author: Basu P, Banerjee D, Singh P, Bhattacharya C, Biswas J

Published: 2013

Efficacy of a Monovalent Human-Bovine (116E) Rotavirus Vaccine in Indian Infants: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, reports on the results of a Phase 3 study to assess the efficacy and tolerability of a monovalent human-bovine rotavirus vaccine (116E) for severe rotavirus gastroenteritis in low-resource urban and rural …

Author: Bhandari N, Rongsen-Chandola T, Bavdekar A, et al.

Published: 2014

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Published: 2007

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Published: 2013

An Epidemiologic Study of Altered Clinical Reactivity to Respiratory Syncytial (RS) Virus Infection in Children Previously Vaccinated With an Inactivated RS Virus Vaccine

This article, published in the American Journal of Epidemiology, describes a study that evaluated altered clinical reactivity to a formalin-inactivated respiratory syncytial virus (RSV) vaccine candidate administered to healthy infants and children …

Author: Kapikian AZ, Mitchell RH, Chanock RM, Shvedoff RA, Stewart CE

Published: 1969

Estimation of the Potential Overall Impact of Human Papillomavirus Vaccination on Cervical Cancer Cases and Deaths

This article, published in Vaccine, reports on a study that aimed to estimate the potential real-life impact of the AS04-adjuvanted HPV-16/18 vaccine on cervical cancer cases and deaths at the country level. The authors found that HPV vaccination …

Author: Van Kriekinge G, Castellsagué X, Cibula D, Demarteau N

Published: 2014

Evaluating the Potential Risks and Benefits of Infant Rotavirus Vaccination in England

This article, published in Vaccine, reports on a risk-benefit analysis of rotavirus vaccination that compared potential vaccine-related risks with estimated vaccine benefits in the 2012 birth cohort in England. The authors estimate that rotavirus …

Author: Clark A, Jit M, Andrews N, Atchison C, Edmunds WJ, Sanderson C

Published: 2014

Evaluation of Vaccines Against Enteric Infections: A Clinical and Public Health Research Agenda for Developing Countries

This article, from the Philosophical Transactions of the Royal Society B, provides a review of the enteric vaccines currently available and their lack of use in developing countries. The author purports that the reasons for this are multiple and …

Author: Clemens J

Published: 2011

Field Evaluation of a Respiratory Syncytial Virus Vaccine and a Trivalent Parainfluenza Virus Vaccine in a Pediatric Population

This article, published the American Journal of Epidemiology, describes a field study conducted in California, United States, that evaluated two formalin inactivated respiratory virus vaccines, a respiratory syncytial virus (RSV) vaccine and a …

Author: Chin J, Magoffin RL, Shearer LA, Schieble JH, Lennette EH

Published: 1969

FLU.gov

This website provides fact sheets, reports, articles, videos, and other resources about influenza symptoms, treatment, prevention, and vaccination.

Author: US Department of Health & Human Services

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