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Disease: Malaria

Total results with these characteristics: 54

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Malaria Vaccine Decision-Making Framework

As the development of malaria vaccines accelerates, work is also underway on the policy front to pave the way for decisions on possible malaria vaccine use. Early planning is crucial to the successful adoption and introduction of a vaccine. To …

Author: PATH

Published: 2012

Malaria Vaccine Initiative

The PATH Malaria Vaccine Initiative's (MVI) mission is to accelerate the development of malaria vaccines and ensure their availability and accessibility in the developing world. The website contains information on malaria and potential …

Author: PATH

Malaria Vaccine Market Consultation: Meeting Report

This report provides an overview of a 2001 meeting of experts that reviewed the malaria vaccine market and identified gaps in essential economic and market information needed to inform decision-makers and ultimately drive the funding/investment …

Author: PATH

Published: 2001

Malaria Vaccine R&D in the Decade of Vaccines: Breakthroughs, Challenges and Opportunities

While progress has been made in reducing malaria mortality with other interventions, vaccines are still urgently needed to further reduce the incidence of clinical disease. The most clinically advanced candidate, RTS,S, is presently undergoing Phase …

Author: Birkett AJ, Moorthy VS, Loucq C, Chitnis CE, Kaslow DC

Published: 2013

Malaria Vaccine Technology Roadmap

The Malaria Vaccine Technology¬†Roadmap was originally published in 2006 to establish a strategic plan for developing and distributing a safe, effective, and affordable vaccine to prevent malaria in children under five years of age in sub-Saharan …

Author: Malaria Vaccine Funders Group

Published: 2013

Malaria Vaccines

This review, published in Frontiers in Bioscience, discusses the life cycle of malaria parasites and the different vaccine candidates aimed at preventing malaria at various stages of the parasites' life cycle. ABSTRACT ONLY. (Learn …

Author: Komisar JL

Published: 2007

MMV at a Glance

This document provides an overview of Medicines for Malaria Venture's activities and achievements.

Author: Medicines for Malaria Venture

Published: 2013

More About Malaria

This web page on the Vaccine Resource Library provides links to PATH's work on malaria, as well as general information about the disease and the current vaccine landscape.

Author: PATH

Published: 2013

Outpatient Upper Respiratory Tract Viral Infections in Children With Malaria Symptoms in Western Kenya

This article, which appeared in the American Journal of Tropical Medicine and Hygiene, describes a cross-sectional study conducted in Kenya’s Nyanza Province to investigate the burden of viral respiratory disease, including influenza, in …

Author: Waitumbi JN, Kuypers J, Anyona SB, et al.

Published: 2010

The PATH Malaria Vaccine Initiative

This fact sheet gives an overview of the PATH Malaria Vaccine Initiative (MVI), a vaccine development program of PATH. Established in 1999, MVI works to accelerate the development of malaria vaccines and to ensure their availability and …

Author: PATH Malaria Vaccine Initiative

Published: 2012

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

This article, published in the New England Journal of Medicine (NEJM), reports results from a pivotal, large-scale Phase 3 trial of RTS,S/AS01 malaria vaccine. When compared to immunization with a control vaccine, infants (aged 6 to 12 weeks at …

Author: The RTS,S Clinical Trials Partnership

Published: 2012

Plasmodium falciparum Malaria Vaccines in Development

This review, published in Expert Review of Vaccines, outlines the developmental status of all malaria vaccine candidates that are currently in human clinical testing against Plasmodium falciparum, as well as selected malaria vaccine candidates at …

Author: Vekemans J, Ballou WR

Published: 2008

Preparing for Malaria Vaccines: African Scientists Speak Out

In this five-minute video, scientist-advocates describe their critical role in closing the gap between the availability of lifesaving interventions and developing countries' access to them. A malaria vaccine could be available in just a few short …

Author: PATH

Published: 2007

Protecting Aluminum-Adjuvanted Vaccines From Freeze Damage

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global …

Author: PATH

Published: 2012

Protecting Child Health for a Promising Future

This fact sheet provides a snapshot of PATH's programs that tackle the leading causes of childhood illness and death: pneumonia, diarrheal disease, and malaria. It profiles PATH's work on new and innovative vaccines, medicines, diagnostics, and …

Author: PATH

Published: 2012

Qualification of Standard Membrane-Feeding Assay with Plasmodium falciparum Malaria and Potential Improvements for Future Assays

Vaccines that interrupt malaria transmission are of increasing interest. A robust functional assay to measure this activity would provide a biologically relevant means of evaluating potential vaccine candidates. This article, published in PLOS ONE, …

Author: Miura K, Deng B, Tullo G, et al.

Published: 2013

Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

This study, published in the New England Journal of Medicine, assessed the feasibility of integrating the RTS,S/AS02D malaria vaccine into a standard expanded program on immunization (EPI) schedule for infants. The study, conducted in …

Author: Abdulla S, Oberholzer R, Juma O, et al.

Published: 2008

Safety of the RTS,S/AS02A Malaria Vaccine in Mozambican Children During a Phase IIb Trial

This study, published in the journal Vaccine, evaluated the safety of the RTS,S/AS02A malaria vaccine in a proof of concept Phase IIb trial in Mozambican children aged one to four years. Overall, the study results indicate that the …

Author: Sacarlal J, Aponte JJ, Aide P, et al.

Published: 2008

State of the Art of New Vaccines: Research and Development

This document analyzes research and development activities for vaccines against infectious diseases of public health importance. Disease groups covered include diarrheal disease, sexually transmitted diseases, respiratory infections, bacterial …

Author: World Health Organization

Published: 2006

Staying the Course? Malaria Research and Development in a Time of Economic Uncertainty

This technical report from the Roll Back Malaria Partnership shines a spotlight on recent trends in investments in malaria research and development (R&D). The report follows up on a 2005 study by the Malaria R&D Alliance to establish a …

Author: PATH

Published: 2011

Summary of Vaccine Stability Data

These documents provide stability data as of November 2012 on commonly used, licensed vaccines and stability data as of May 2012 from available data on novel, investigational vaccine formulations. Data are sorted by vaccine in a table format in both …

Author: PATH, Working in Tandem Ltd.

Published: 2012

USAID and PATH: Working Together to Improve Global Health

PATH and the US Agency for International Development (USAID) work together to improve global health around the world. This fact sheet highlights the more than 10 PATH projects—including PATH's Malaria Vaccine Initiative—that are …

Author: PATH

Published: 2013

WHO Policy Development Processes for a New Vaccine: Case Study of Malaria Vaccines

This article, published in Malaria Journal, analyzed the World Health Organization policy development process to predict its course for a malaria vaccine. Data needs for a malaria vaccine include safety; the demonstration of efficacy in a range of …

Author: Milstien J, Cardenas V, Cheyne J, Brooks A

Published: 2010

World Malaria Report 2008

This report provides key information on the burden of malaria worldwide, as well as important data on efforts to prevent and control the disease. Also included are detailed profiles of 30 countries with a high burden …

Author: World Health Organization

Published: 2008

World Malaria Report 2009

This report summarizes information received from 108 malaria endemic countries and other sources and updates the analysis presented in the 2008 Report. It highlights progress made in meeting the World Health Assembly targets for malaria to be …

Author: World Health Organization

Published: 2009

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