Published in the journal Vaccine, this article discusses the importance of creating reliable, long-term demand for the next generation of enteric vaccines, including new rotavirus, Shigella, and ETEC vaccines and priorities for achieving this …

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration …

This study, published in the Journal of Infectious Diseases, of children presenting with mild to severe diarrhea and dehydration at a hospital in Peru describes rotavirus serotypes and risk factors for infection, and offers support for the …

From the Weekly Epidemiological Record, this report is from an international consultative meeting on ETEC to examine the most recent epidemiological data from the field, identify gaps in the laboratory methods for strain …

This web page provides information on ETEC disease burden and vaccine development, as well as useful links.

This web page provides information on ETEC, its transmission, prevention of the disease, and more.

This article was published in Clinical Microbiology Reviews. ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial …

This study, published in Emerging Infectious Diseases, provides evidence that the relationship between the environment and the location of meningitis epidemics is quantifiable. The study proposes a model based on environmental …

This article, published in the journal Vaccine, emphasizes Group A Neisseria meningitidis as a health problem in Africa and disccuses the potential for a proactive control strategy for epidemic meningitis with the use of …

This article, published in the American Journal of Epidemiology, describes a study that evaluated altered clinical reactivity to a formalin-inactivated respiratory syncytial virus (RSV) vaccine candidate administered to healthy infants and children …

Published in Clinical Infectious Diseases, this article discusses the current epidemiological profile of meningococcal disease and the vaccines that are currently available in the United States. The article also outlines what would be required for a …

This article, published in Tropical Medicine & International Health, describes the results of two years of surveillance for Japanese encephalitis (JE) disease in Cambodian children aged 15 years and under at six sentinel …

This study, published in the Bulletin of the World Health Organization, used retrospective surveillance to identify cases of laboratory-diagnosed bacterial meningitis in Niamey, Niger, from 1981 to 1996. The study analyzed the cases …

This review of 30 years worth of published data provided insight into the burden of disease and the emergence of new genotypes in Kenya, indicating a need for continued surveillance. ABSTRACT ONLY. (Learn how users in developing countries can …

This article provides a historical overview of Japanese encephalitis (JE) in India since the first detection of JE virus activity in 1952 until the 2006 introduction of JE vaccine in high-risk states and expansion of vaccination efforts in …

This slide presentation gives an overview of the epidemiology of JE and can be adapted for individual use.

Neisseria meningitidis causes meningococcal disease, a severe bacterial infection of the bloodstream or meninges, worldwide. The disease is most common among young children, but the existing polysaccharide vaccines have been sparsely used because …

This article, published in Neurological Research, discusses the changes in the epidemiology of meningococcal disease in Latin America and comments on the development and potential impact of new vaccines for the prevention of the disease. The authors …

This literature review, published in the Pan American Journal of Public Health, was performed to assess the disease burden and epidemiology of rotavirus diarrhea in Latin America. ABSTRACT ONLY. (Learn how users in developing countries can …

This study, published in the Bulletin of the World Health Organization, reviews the epidemiology and disease burden of rotavirus diarrhea among children at hospitals and clinics in African countries, covering the period 1975–1992.

This article, published in Clinical and Vaccine Immunology, reports on a study that resulted in the development of a new pneumococcal reference serum to replace the dwindling stocks of Lot 89SF, the reference standard serum pool used since 1990. The …

This article, published in The Lancet Infectious Diseases, estimates the global mortality associated with the first 12 months of the 2009 influenza A/H1N1 virus pandemic. Results of the analysis estimate that respiratory and cardiovascular …

This web page provides an estimate of child mortality due to Haemophilus influenzae type b (Hib) and pneumococcal infections in 2008. It also contains a link to a chart of death rates due to these infections, broken down by region and HIV status.

To establish a relation between deaths due to acute respiratory infections (ARI) and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence …

This article, published in Influenza and Other Respiratory Viruses, details the results of a meta-analysis conducted to provide insights into the global impact of the 2009 influenza A(H1N1) pandemic. The study estimates overall and age-specific …