Browse resources

Total results with these characteristics: 1437

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Published: 2007

Efficacy of Nine-valent Pneumococcal Conjugate Vaccine Against Pneumonia and Invasive Pneumococcal Disease in The Gambia: Randomized Double-Blind, Placebo-Controlled Trial

Published in The Lancet, this study aims to assess the efficacy of a nine-valent pneumococcal conjugate vaccine in children through a randomised, placebo-controlled, double-blind trial in eastern Gambia. Children age 6–51 weeks were randomly …

Author: Cutts U, Zaman SMA, Enwere G, et al.

Published: 2005

Efficacy of Pentavalent Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Infants in Developing Countries in Asia: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, assesses the clinical efficacy of the pentavalent, live oral rotavirus vaccine for the prevention of severe rotavirus gastroenteritis in infants in Bangladesh and Vietnam. Study results demonstrated vaccine …

Author: Zaman K, Dang DA, Victor JC, et al.

Published: 2010

Efficacy of Pentavalent Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Infants in Developing Countries in Sub-Saharan Africa: A Randomised, Double-Blind, Placebo-Controlled Trial

This article, published in The Lancet, shares results of an efficacy study of the pentavalent, live oral rotavirus vaccine in Ghana, Kenya, and Mali. Results showed 39.3 percent efficacy against  severe rotavirus gastroenteritis. The authors …

Author: Armah GE, Sow SO, Breiman RF, et al.

Published: 2010

Efficacy of Pneumococcal Conjugate Vaccines and Their Effort on Carriage and Antimicrobial Resistance

Pneumococcal conjugate vaccines have shown a high degree of success in preventing pneumococcal bacteraemia in children. They also reduce the acquisition of carriage of vaccine serotypes in the nasopharynx, and reduce otitis media caused by those …

Author: Klugman K

Published: 2001

Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age

This study, published in the New England Journal of Medicine, evaluated the efficacy of the RTS,S malaria vaccine given with a more immunogenic adjuvant system (AS01E) than one used in a previous study (AS02A). The study was conducted in …

Author: Bejon P, Lusingu J, Olotu A, et al.

Published: 2008

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Published: 2013

Efficacy of the Human Rotavirus Vaccine RIX4414 in Malnourished Children

This study, published in the Journal of Infectious Diseases, determined that the Rotarix® vaccine produced by GlaxoSmithKline decreased the incidence severe gastroenteritis caused by rotavirus at comparable rates among well-nourished and …

Author: Perez-Schael I, Salinas B, Tomat M, et al.

Published: 2007

Eliminating Epidemic Group A Meningococcal Meningitis in Africa Through a New Vaccine

This article, published in Health Affairs, discusses a new affordable vaccine against Group A meningococcus, the most common cause of large and often fatal African epidemics of meningitis, that was introduced in Burkina Faso, Mali, and Niger in …

Author: LaForce FM, Okwo-Bele J-M

Published: 2011

Elimination of Haemophilus influenzae type b (Hib) Disease From The Gambia After the Introduction of Routine Immunisation With a Hib Conjugate Vaccine: A Prospective Study

Routine immunization of infants in The Gambia with a Haemophilus influenzae type b (Hib) polysaccharide-tetanus toxoid conjugate vaccine began in May 1997. This article, published in The Lancet, reports on a study that investigated the effectiveness …

Author: Adegbola RA, Secka O, Lahai G, et al.

Published: 2005

E-medicine: Japanese Encephalitis

This article provides a comprehensive overview of the disease.

Author: Kallen A

Published: 2002

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

This article, published in the New England Journal of Medicine, describes the findings of the US Centers for Disease Control and Prevention's Novel Swine-Origin Influenza A(H1N1) Virus Investigation Team from their assessment of the …

Author: Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team

Published: 2009

Emergence of Serogroup X Meningococcal Disease in Africa: Need for a Vaccine

This article, published in Vaccine, describes how and why serogroup X meningococcal disease has emerged in Africa in recent years. It asserts that while no licensed vaccine is available against serogroup X meningococci, following the introduction of …

Author: Xie O, Pollard AJ, Mueller JE, Norheim G

Published: 2013

Emergency or Routine Vaccination Against Meningococcal Disease in Africa?

This comment, published in The Lancet, is based on a review of the study "Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa." The author concludes that …

Author: Peltola H

Published: 2000

Emergency Vaccination Against Epidemic Meningitis in Ghana: Implications for the Control of Meningococcal Disease in West Africa

This article, published in The Lancet, assessed the potential effects of different vaccination strategies against meningococcal disease using data from the 1997 meningococcal outbreak in northern Ghana. Using a simple mathematical model, …

Author: Woods CW, Armstrong G, Sackey SO, et al.

Published: 2000

The Emerging Adolescent Agenda: HPV Vaccine, AIDS Prevention Research, and the New Opportunities for Reaching the Young People of the World

This chapter from an annual report explores why licensure of the vaccine against human papillomavirus (HPV) presents the AIDS vaccine field with new opportunities. The report discusses how to advocate for financing commitments to ensure widespread …

Author: AIDS Vaccine Advocacy Coalition

Published: 2006

Enhanced Pulmonary Histopathology is Observed in Cotton Rats Immunized with Formalin-Inactivated Respiratory Syncytial Virus (RSV) or Purified F Glycoprotein and Challenged With RSV 3-6 Months After Immunization

The authors of this study, published in Vaccine, compared formalin-inactivated (FI) RSV, purified F glycoprotein in alum, and RSV infection (intranasal) for their immunogenicity, efficacy, and ability to enhance pulmonary histopathology during RSV …

Author: Murphy BR, Sotnikov AV, Lawrence LA, Banks SM, Prince GA

Published: 1990

Ensuring Access to HPV Vaccines Through Integrated Services: A Reproductive Health Perspective

This article, published in the Bulletin of the World Health Organization, describes avenues for service delivery of human papillomavirus (HPV) vaccines and critical information gaps that must be bridged in order to inform future sexual and …

Author: Pollack AE, Balkin M, Edouard L, Cutts F, and Broutet N on behalf of the WHO/United Nations Population Fund Working Group on Sexual and Reproductive Health and HPV Vaccines

Published: 2007

Ensuring That Developing Countries Have Access to New Healthcare Products: The Role of Product Development Partnerships

According to this article published in the eJournal Innovation Strategies Today, product development partnerships (PDPs) are generating an increasing flow of health products, including vaccines, for diseases prevalent in developing countries. …

Author: Brooks AD, Wells WA, McLean TD, et al.

Published: 2010

Enteric Diseases

This web page provides information in enteric diseases, including NIAID-supported research, meeting summaries, news releases, and resources for researchers.

Author: US National Institute for Allergy and Infectious Diseases (NIAID)

Enteric Infections and the Vaccines to Counter Them: Future Directions

Published in the journal Vaccine, this article discusses the importance of creating reliable, long-term demand for the next generation of enteric vaccines, including new rotavirus, Shigella, and ETEC vaccines and priorities for achieving this …

Author: Levine M

Published: 2006

Enteric Infections, Diarrhea, and Their Impact on Function and Development

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration …

Author: Petri Jr. WA, Miller M, Binder HJ, et al.

Published: 2008

Enterotoxigenic Escherichia coli: Advances in Technical and Laboratory Aspects of Research and Development of Vaccines

From the Weekly Epidemiological Record, this report is from an international consultative meeting on ETEC to examine the most recent epidemiological data from the field, identify gaps in the laboratory methods for strain …

Author: World Health Organization

Published: 2008

Enterotoxigenic Escherichia coli (ETEC)

This web page provides information on ETEC, its transmission, prevention of the disease, and more.

Author: US Centers for Disease Control and Prevention

Enterotoxigenic Escherichia coli in Developing Countries: Epidemiology, Microbiology, Clinical Features, Treatment, and Prevention

This article was published in Clinical Microbiology Reviews. ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial …

Author: Qadri F, Svennerholm AM, Faruque AS, Sack RB

Published: 2005