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Total results with these characteristics: 1524

Developing New Vaccines Against Pneumonia and Other Pneumococcal Diseases

This fact sheet, issued by PATH, outlines PATH's pneumococcal vaccine project from a technical perspective, including an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of vaccines …

Author: PATH

Published: 2014

Development and Clinical Evaluation of Prevnar 13, a 13-Valent Pneumocococcal CRM197 Conjugate Vaccine

This article, published in the Annals of the New York Academy of Sciences, discusses the development, clinical evaluation, and postlicensure impact of the 13-valent pneumococcal CRM(197) protein conjugate vaccine, PCV13, (Prevnar 13®). ABSTRACT …

Author: Gruber WC, Scott DA, Emini EA

Published: 2012

Development and Implementation of a National Programme for the Management of Severe and Very Severe Pneumonia in Children in Malawi

This article, published in PLoS Medicine, provides an overview of the development and implementation of a national program for the management of severe and very severe childhood pneumonia in Malawi. Based on a successful delivery model used by the …

Author: Enarson PM, Gie R, Enarson DA, Mwansambo C

Published: 2009

Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant

This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …

Author: Holmgren J, Bourgeois L, Carlin N, et al.

Published: 2013

Development and Technology Transfer of Haemophilus influenzae type b Conjugate Vaccines for Developing Countries

This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …

Author: Beurret M, Hamidi A, Kreeftenberg H

Published: 2012

Development of a Fast-Dissolving Tablet Formulation of a Live Attenuated Enterotoxigenic E. coli Vaccine Candidate

A fast-dissolving tablet (FDT) that could be packaged in a compact stackable blister sheet is a potentially attractive option for formulating oral vaccines, since it would minimally impact the cold chain and could potentially be administered …

Author: Lal M, Priddy S, Bourgeois L, et al.

Published: 2013

Development of a Freeze-Stable Formulation for Vaccines Containing Aluminum Salt Adjuvants

This article, published in Vaccine, describes an approach to minimize reliance on the proper implementation of the cold chain to protect vaccines from freeze-thaw inactivation. By including PEG 300, propylene glycol, or glycerol in a hepatitis B …

Author: Jones Braun L, Tyagi A, Perkins S, et al.

Published: 2009

Development of a Group A Meningococcal Conjugate Vaccine, MenAfriVac™

Group A meningococcal disease has been an important public health problem in sub-Saharan Africa for over a century. From 2003 to 2009 a monovalent group A conjugate vaccine, MenAfriVac™, was developed through an innovative public/private …

Author: Frasch C, Preziosi M-P, LaForce FM

Published: 2012

Development of a Humanized Monoclonal Antibody (MEDI-493) With Potent In Vitro and In Vivo Activity Against Respiratory Syncytial Virus

This article, published in The Journal of Infectious Diseases, details a preclinical study evaluating the ability of a humanized monoclonal antibody, MEDI-493 (later named palivizumab and marketed at Synagis®), to recognize a conserved …

Author: Johnson S, Oliver C, Prince GA, et al.

Published: 1997

Development of a Low-Dose Challenge Model for Evaluation of Vaccines for Enterotoxigenic E. coli (ETEC) in Volunteers

This presentation from the Vaccines for Enteric Diseases conference provides results from a clinical trial that found the human challenge model currently being used to test vaccines against enterotoxigenic Escherichia coli (ETEC) is utilizing a …

Author: Harro C, DeNearing B, Marcum A, et al.

Published: 2009

Development of Antibodies Against the Putative Proteinase Maturation Protein A in Relation to Pneumococcal Carriage and Otitis Media

Published in FEMS Immunology and Medical Microbiology, this article examines serum anti-pneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal …

Author: Bogaert D, Holmlund E, Lahdenkari M, et al.

Published: 2006

Development of Lactococcal GEM-Based Pneumococcal Vaccines

Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed …

Author: Audouy S, van Selm S, van Roosmalen M, et al.

Published: 2007

The Development of Live, Attenuated Rotavirus Vaccines: A Manufacturer's Resource Guide

This guide is a compilation of publicly available information about the manufacturing process of rotavirus vaccines, and aims to provide a resource for manufacturers interested in developing and registering an attenuated, oral rotavirus vaccine. …

Author: PATH, GAVI Alliance

Published: 2006

Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries

This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …

Author: Heidt PJ, Walker RI, Rusch V, eds.

Published: 2011

Development of Vaccines Against Meningococcal Disease

This article, published in the Lancet, reviews the currently available vaccines against meningococcal disease, as well as research and development efforts toward the development of additional vaccines against the disease. ABSTRACT …

Author: Jódar L, Feavers IM, Salisbury D, Granoff DM

Published: 2002

Diagnostic and Laboratory Testing Aspects of JE

This slide presentation give an overivew of the diagnostic and laboratory testing aspects of JE and can be apdated to fit your audience.

Author: PATH

Published: 2007

Diarrheal Disease: Solutions to Defeat a Global Killer

Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, …

Author: PATH

Published: 2009

Diarrhoea: Why Children Are Still Dying and What Can Be Done

This joint report from the World Health Organization and the United Nations Children's Fund (UNICEF) focuses attention on the prevention and management of diarrheal diseases. It examines the latest available information on the burden of childhood …

Author: World Health Organization, United Nations Children's Fund

Published: 2009

Diarrhoea-Related Hospitalizations in Children Before and After Implementation of Monovalent Rotavirus Vaccination in Mexico

This article, published in the Bulletin of the World Health Organization, reports on a study that compared the incidence of diarrhea in young children before and after the national introduction of monovalent rotavirus vaccine in Mexico. The results …

Author: Esparza-Aguilar M, Gastañaduy PA, Sánchez-Uribe E, et al.

Published: 2014

Direct and Indirect Effects of Rotavirus Vaccination Upon Childhood Hospitalizations in 3 US Counties, 2006–2009

This article, published in Clinical Infectious Diseases, is about an active, population-based surveillance for rotavirus gastroenteritis hospitalizations in three United States counties to assess the impact of rotavirus vaccines. The study …

Author: Payne DC, Staat MA, Edwards KM, et al.

Published: 2011

Direct-Drive Solar Vaccine Refrigerators—A New Choice for Vaccine Storage

This evidence brief developed by project Optimize is directed toward supply chain managers in low- and middle-income countries and provides information about direct-drive solar refrigerators, which may be a good option for vaccine storage in areas …

Author: PATH, World Health Organization

Published: 2013

Directory of Immunization Resources

This web page provides an extensive directory of immunization resources for health care professionals, including information on particular diseases and vaccines, immunization schedules, and frequently asked questions. The resources are gathered from …

Author: Immunization Action Coalition

Disease Burden Due to Enterotoxigenic Escherichia coli (ETEC) in the First Two Years of Life in an Urban Community in Bangladesh

Published in Infection and Immunity, a cohort of 321 children were followed from birth up to two years to determine the incidence of enterotoxigenic Escherichia coli (ETEC) in Bangladesh. Children with ETEC diarrhea were underweight and stunted …

Author: Qadri F, Saha A, Ahmed T

Published: 2007

Disease Control Priorities in Developing Countries, Second Edition

A comprehensive global health examination, this book contributes substantially to global initiatives to improve the health of all peoples by providing a multidisciplinary understanding of fundamental issues and challenges, as well as effective …

Author: Disease Control Priorities Project

Published: 2008

Disease Outbreak News

This web page provides frequently updated information about current disease outbreaks, as well as disease-specific archives of past alerts and links to related resources.

Author: World Health Organization