This article, published in Clinical and Vaccine Immunology, reports on a study that resulted in the development of a new pneumococcal reference serum to replace the dwindling stocks of Lot 89SF, the reference standard serum pool used since 1990. The …

This article, published in The Lancet Infectious Diseases, estimates the global mortality associated with the first 12 months of the 2009 influenza A/H1N1 virus pandemic. Results of the analysis estimate that respiratory and cardiovascular …

This web page provides an estimate of child mortality due to Haemophilus influenzae type b (Hib) and pneumococcal infections in 2008. It also contains a link to a chart of death rates due to these infections, broken down by region and HIV status.

To establish a relation between deaths due to acute respiratory infections (ARI) and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence …

This article, published in Influenza and Other Respiratory Viruses, details the results of a meta-analysis conducted to provide insights into the global impact of the 2009 influenza A(H1N1) pandemic. The study estimates overall and age-specific …

Published in The Bulletin of the World Health Organization, this study provides estimates of diarrhea mortality at country, regional, and global levels and discusses interventions to reduce childhood mortality caused by diarrheal disease.

Published in the journal Vaccine, this article describes a method for correlating pneumococcal anticapsular antibody responses of infants immunized with pneumococcal conjugate (PnC) vaccine (Prevenar) with clinical protection from invasive …

This article, published in Revista Médica de Chile, outlines an economic model that determined rotavirus vaccination is a cost-effective intervention that can effectively reduce the disease burden and healthcare costs of rotavirus …

This article, published in the Weekly Epidemiological Record, discusses the outcome of a meeting of global, regional, and country-level rotavirus experts and immunization opinion leaders who gathered to provide guidance on evaluating and …

This study, published in the Journal of Infectious Diseases, explores the biological plausibility of intussusception caused by natural rotavirus infection.

This article, published in Vaccine, estimates the cost-effectiveness of introducing the rotavirus vaccine RotaTeq® in Ghana. The authors estimated the average costs of treating children with diarrhea in the Ashanti region of Ghana as inpatients …

Before the 2010 to 2011 introduction of the first serogroup A meningococcal conjugate vaccine developed solely for Africa (MenAfriVac), evaluations of the existing meningitis surveillance in Burkina Faso and Mali were conducted to assess the …

This document summarizes the results of a study of out-of-the-cold-chain approaches for improving on-time delivery of birth doses of the hepatitis B vaccine in rural areas of China. The study concluded that this is a safe and effective way to …

This article, published in The Journal of Health, Population, and Nutrition, summarizes the general steps required for meningococcal vaccine development, reviews the use of immunogenicity criteria as a licensing strategy for new meningococcal …

This article, published in BMC Public Health, summarizes the results of a literature review and an expert opinion exercise to evaluate the best course of protection against respiratory syncytial virus (RSV) for children in the developing world, …

This study, published in Epidemiology and Infection, evaluated an ecological model based on absolute humidity and land cover type to predict the location of meningitis epidemics in the Sahelian region known as the African Meningitis Belt. The …

From the American Journal of Tropical Medicine and Hygiene, this study evaluates the sensitivity, specificity, and usability of three commercially-available kits for Japanese encephalitis laboratory diagnostics.

This article, from the Philosophical Transactions of the Royal Society B, provides a review of the enteric vaccines currently available and their lack of use in developing countries. The author purports that the reasons for this are multiple and …

Published in The Lancet, this review summarises available data on the burden of pneumococcal disease and the safety and efficacy of PCVs in HIV-infected children. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to …

This web page contains a dossier that includes statements of support for improved cervical cancer control from governments, organizations, and individuals in Africa, Asia, Latin America, and other regions. The letters, video messages, editorials, …

Since 1993 the Pan American Health Organization has coordinated a surveillance network with the National Reference Laboratories of Argentina, Brazil, Chile, Colombia, Mexico and Uruguay aimed at monitoring capsular types and antimicrobial …

This article, published in Expert Review of Vaccines, discusses morbidity and mortality due to meningococcal serogroups A, C, Y, and W-135 and the ability of monovalent meningococcal serogroup C conjugate (MCC) vaccines to reduce the burden of …

This fact sheet highlights PATH's multifaceted approach to expanding vaccine solutions against pandemic and seasonal influenza that are optimal for the developing world. It describes our efforts to advance the development of promising new …

This fact sheet summarizes the technical efforts and objectives of PATH's non-replicating rotavirus vaccine (NRRV) development project. It outlines the vaccine candidates under evaluation and primary partners, as well as the rationale for the NRRV …

Good cold chain practice is essential to maintain full immunogenicity of vaccines. This article, published in Vaccine, reports on a study that aimed to identify the likelihood and extent of exposure to inappropriate temperatures in the vaccine cold …