This fact sheet highlights PATH's work to develop safe, effective, and affordable vaccines against Shigella and enterotoxigenic Escherichia coli, two of the leading bacterial causes of diarrheal disease.

This fact sheet, issued by PATH, outlines PATH's pneumococcal vaccine project from a technical perspective, including an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of vaccines …

This article, published in PLoS Medicine, provides an overview of the development and implementation of a national program for the management of severe and very severe childhood pneumonia in Malawi. Based on a successful delivery model used by the …

This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …

This article, published in Vaccine, describes an approach to minimize reliance on the proper implementation of the cold chain to protect vaccines from freeze-thaw inactivation. By including PEG 300, propylene glycol, or glycerol in a hepatitis …

Group A meningococcal disease has been an important public health problem in sub-Saharan Africa for over a century. From 2003 to 2009 a monovalent group A conjugate vaccine, MenAfriVac™, was developed through an innovative public/private …

This article, published in The Journal of Infectious Diseases, details a preclinical study evaluating the ability of a humanized monoclonal antibody, MEDI-493 (later named palivizumab and marketed at Synagis®), to recognize a conserved …

This presentation from the Vaccines for Enteric Diseases conference provides results from a clinical trial that found the human challenge model currently being used to test vaccines against enterotoxigenic Escherichia coli (ETEC) is utilizing a …

Published in FEMS Immunology and Medical Microbiology, this article examines serum anti-pneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal …

Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed …

This guide is a compilation of publicly available information about the manufacturing process of rotavirus vaccines, and aims to provide a resource for manufacturers interested in developing and registering an attenuated, oral rotavirus vaccine. …

This article, which appeared in the Old Herborn University Seminar Monograph, provides a summary of the discussions at a workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the …

This article, published in the Lancet, reviews the currently available vaccines against meningococcal disease, as well as research and development efforts toward the development of additional vaccines against the disease. ABSTRACT …

This slide presentation give an overivew of the diagnostic and laboratory testing aspects of JE and can be apdated to fit your audience.

This article, published in The Lancet, discusses diarrheal disease in children in the developed and developing worlds, prevention and treatment options, and what we can learn from looking at diarrheal disease in developed and …

Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, …

This joint report from the World Health Organization and the United Nations Children's Fund (UNICEF) focuses attention on the prevention and management of diarrheal diseases. It examines the latest available information on the burden of childhood …

This article, published in Clinical Infectious Diseases, is about an active, population-based surveillance for rotavirus gastroenteritis hospitalizations in three United States counties to assess the impact of rotavirus vaccines. The study …

This web page provides an extensive directory of immunization resources for health care professionals, including information on particular diseases and vaccines, immunization schedules, and frequently asked questions. The resources are gathered from …

Published in Infection and Immunity, a cohort of 321 children were followed from birth up to two years to determine the incidence of enterotoxigenic Escherichia coli (ETEC) in Bangladesh. Children with ETEC diarrhea were underweight and stunted …

A comprehensive global health examination, this book contributes substantially to global initiatives to improve the health of all peoples by providing a multidisciplinary understanding of fundamental issues and challenges, as well as effective …

This web page provides frequently updated information about current disease outbreaks, as well as disease-specific archives of past alerts and links to related resources.

This series of fact sheets describes symptoms of infection as well as the benefits and risk of vaccination for 14 diseases, including hepatitis B, Haemophilus influenzae type b, influenza, pneumococcal disease, polio, and rotavirus. There …

The paper reports on a field trial of disposal and destruction methods (including autocombustion incinerators) in the two countries.

In the 1960s a respiratory syncytial virus (RSV) vaccine was evaluated in infants and young children. Vaccinees who received formalin-inactivated RSV during early infancy developed more serious lower-respiratory-tract disease when infected with the …