Total results with these characteristics: 1431
- Delivering MenAfriVac Using the Controlled Temperature Chain Approach
In November 2012, the first immunization campaign to use a controlled temperature chain (CTC) took place in northern Benin. This photo set by project Optimize contains images taken during the campaign, where more than 155,000 people were vaccinated …
Author: PATH, World Health Organization
- Delivering Vaccines: A Cost Comparison of In-Country Vaccine Transport Container Options
Project Optimize undertook a cost-comparison case study of five container options for vaccine transport from the national to the regional level in Senegal. This report may be used as a starting point for other country vaccine programs weighing …
Author: PATH, World Health Organization
- Designing Safe Syringe Disposal Systems for Immunization Services
This 30-page manual for program managers helps guide decision-making related to safe syringe disposal at the district level. A range of disposal methods and issues are covered, including practical advice on incineration (with details on two small …
- Designing Vaccines for Developing-Country Populations: Ideal Attributes, Delivery Devices, and Presentation Formats
This article, published in Procedia in Vaccinology, discusses the importance of designing vaccines with traits that will minimize complications for immunization programs and increase the likelihood of successful adoption. The article also summarizes …
Author: Kristensen D, Zaffran M
- Desirable Attributes of Vaccines for Deployment in Low-Resource Settings
This article, published in the Journal of Pharmaceutical Sciences, discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including enhanced stability and efficient packaging, that can help to …
Author: Chen D, Zehrung D
- Detecting Meningococcal Meningitis Epidemics in Highly-Endemic African Countries
This article, published in the World Health Organization's (WHO's) Weekly Epidemiological Record, provides the WHO recommendation for detecting and responding to meningococcal meningitis epidemics in highly-endemic countries in Africa. In each …
Author: World Health Organization
- Developing a Vision for Immunization Supply Systems in 2020: Landscape Analysis Summaries
Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses …
Author: PATH, World Health Organization
- Developing New Vaccines Against Pneumonia and Other Pneumococcal Diseases
This fact sheet, issued by PATH, outlines PATH's pneumococcal vaccine project from a technical perspective, including an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of vaccines …
- Development and Clinical Evaluation of Prevnar 13, a 13-Valent Pneumocococcal CRM197 Conjugate Vaccine
This article, published in the Annals of the New York Academy of Sciences, discusses the development, clinical evaluation, and postlicensure impact of the 13-valent pneumococcal CRM(197) protein conjugate vaccine, PCV13, (Prevnar 13®). ABSTRACT …
Author: Gruber WC, Scott DA, Emini EA
- Development and Implementation of a National Programme for the Management of Severe and Very Severe Pneumonia in Children in Malawi
This article, published in PLoS Medicine, provides an overview of the development and implementation of a national program for the management of severe and very severe childhood pneumonia in Malawi. Based on a successful delivery model used by the …
Author: Enarson PM, Gie R, Enarson DA, Mwansambo C
- Development and Preclinical Evaluation of Safety and Immunogenicity of an Oral ETEC Vaccine Containing Inactivated E. coli Bacteria Overexpressing Colonization Factors CFA/I, CS3, CS5 and CS6 Combined With a Hybrid LT/CT B Subunit Antigen, Administered Alone and Together With dmLT Adjuvant
This article, published in Vaccine, describes the development and preclinical testing of new oral vaccine against enterotoxigenic Escherichia coli (ETEC) administered alone and in combination with an adjuvant. The studies found that oral …
Author: Holmgren J, Bourgeois L, Carlin N, et al.
- Development and Technology Transfer of Haemophilus influenzae type b Conjugate Vaccines for Developing Countries
This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …
Author: Beurret M, Hamidi A, Kreeftenberg H
- Development of a Fast-Dissolving Tablet Formulation of a Live Attenuated Enterotoxigenic E. coli Vaccine Candidate
A fast-dissolving tablet (FDT) that could be packaged in a compact stackable blister sheet is a potentially attractive option for formulating oral vaccines, since it would minimally impact the cold chain and could potentially be administered …
Author: Lal M, Priddy S, Bourgeois L, et al.
- Development of a Freeze-Stable Formulation for Vaccines Containing Aluminum Salt Adjuvants
This article, published in Vaccine, describes an approach to minimize reliance on the proper implementation of the cold chain to protect vaccines from freeze-thaw inactivation. By including PEG 300, propylene glycol, or glycerol in a hepatitis B …
Author: Jones Braun L, Tyagi A, Perkins S, et al.
- Development of a Group A Meningococcal Conjugate Vaccine, MenAfriVac™
Group A meningococcal disease has been an important public health problem in sub-Saharan Africa for over a century. From 2003 to 2009 a monovalent group A conjugate vaccine, MenAfriVac™, was developed through an innovative public/private …
Author: Frasch C, Preziosi M-P, LaForce FM
- Development of a Humanized Monoclonal Antibody (MEDI-493) With Potent In Vitro and In Vivo Activity Against Respiratory Syncytial Virus
This article, published in The Journal of Infectious Diseases, details a preclinical study evaluating the ability of a humanized monoclonal antibody, MEDI-493 (later named palivizumab and marketed at Synagis®), to recognize a conserved …
Author: Johnson S, Oliver C, Prince GA, et al.
- Development of a Low-Dose Challenge Model for Evaluation of Vaccines for Enterotoxigenic E. coli (ETEC) in Volunteers
This presentation from the Vaccines for Enteric Diseases conference provides results from a clinical trial that found the human challenge model currently being used to test vaccines against enterotoxigenic Escherichia coli (ETEC) is utilizing a …
Author: Harro C, DeNearing B, Marcum A, et al.
- Development of Antibodies Against the Putative Proteinase Maturation Protein A in Relation to Pneumococcal Carriage and Otitis Media
Published in FEMS Immunology and Medical Microbiology, this article examines serum anti-pneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal …
Author: Bogaert D, Holmlund E, Lahdenkari M, et al.
- Development of Lactococcal GEM-Based Pneumococcal Vaccines
Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed …
Author: Audouy S, van Selm S, van Roosmalen M, et al.
- The Development of Live, Attenuated Rotavirus Vaccines: A Manufacturer's Resource Guide
This guide is a compilation of publicly available information about the manufacturing process of rotavirus vaccines, and aims to provide a resource for manufacturers interested in developing and registering an attenuated, oral rotavirus vaccine. …
Author: PATH, GAVI Alliance
- Development of Strategies to Overcome Barriers to Effective Mucosal Immunization of Infants in Developing Countries
This issue of the Old Herborn University Seminar Monograph provides a summary of the discussions at an expert workshop hosted by the Old Herborn University Foundation in June 2010. The discussions were held to examine the mechanisms that may …
Author: Heidt PJ, Walker RI, Rusch V, eds.
- Development of Vaccines Against Meningococcal Disease
This article, published in the Lancet, reviews the currently available vaccines against meningococcal disease, as well as research and development efforts toward the development of additional vaccines against the disease. ABSTRACT …
Author: Jódar L, Feavers IM, Salisbury D, Granoff DM
- Diagnostic and Laboratory Testing Aspects of JE
This slide presentation give an overivew of the diagnostic and laboratory testing aspects of JE and can be apdated to fit your audience.
- Diarrheal Disease: Solutions to Defeat a Global Killer
Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, …
- Diarrhoea: Why Children Are Still Dying and What Can Be Done
This joint report from the World Health Organization and the United Nations Children's Fund (UNICEF) focuses attention on the prevention and management of diarrheal diseases. It examines the latest available information on the burden of childhood …
Author: World Health Organization, United Nations Children's Fund