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Total results with these characteristics: 62

Topic: Delivery technologies

Page 1 of 4
Access to Vaccine Technologies in Developing Countries: Brazil and India

The authors of this study, published in the journal Vaccine, analyzed advantages and disadvantages of different ways vaccine manufacturers access new technologies. Among the methods considered were collaborations with academia and research …

Author: Milstien J, Gaule G, Kaddar M

Publication date: 2007

Access to Vaccines Index 2017

The Access to Vaccines Index is a publicly available tool that assesses the world's largest vaccine companies based on their ability to improve access to vaccines. With cross-cutting analyses of each vaccine company's efforts to develop, …

Author: Access to Medicine Foundation

Publication date: 2017

Best Infection Control Practices for Interdermal, Subcutaneous, and Intramuscular Needle Injections

From the Bulletin of the World Health Organization, this article discusses evidence-based guidelines for making injections safer. Abstracts are available in Spanish, French, and Arabic.

Author: Hutin Y, Hauri A, Chiarello L, et al.

Publication date: 2003

Building Next Generation Immunization Supply Chains

This supplement to Vaccine contains 31 articles addressing the role of immunization supply chains (iSC) in expanding vaccine coverage, as well as current challenges, successful pilots, and innovative upstream solutions towards next-generation iSC. …

Author: Lee BY, Schreiber B, Rao R, eds.

Publication date: 2017

Challenges of Vaccine Presentation and Delivery: How Can We Design Vaccines to Have Optimal Programmatic Impact?

This article, published in Vaccine, presents three cases studies of novel approaches to immunization program delivery that represent the potential for improving vaccine accessibility in resource-constrained environments. The case studies feature …

Author: Giersing BK, Kahn A-L, Jarrahian C, et al.

Publication date: 2017

Clinical Performance and Safety of the ID Adapter, a Prototype Intradermal Delivery Technology for Vaccines, Drugs, and Diagnostic Tests

The authors of this article, published in Procedia in Vaccinology, discuss a Phase 1 clinical study conducted to evaluate the intradermal (ID) adapter, a prototype intradermal delivery aid, for safety and precision of injection. The authors present …

Author: Jarrahian C, Zehrung D, Saxon E, Griswold E, Klaff L

Publication date: 2012

The Cure That Kills

This paper examines the health risks posed by unsafe injections in Africa and outlines some of the programs that are helping reduce these risks.

Author: Practical Patient Care

Publication date: 2008

Designing Vaccines for Developing-Country Populations: Ideal Attributes, Delivery Devices, and Presentation Formats

This article, published in Procedia in Vaccinology, discusses the importance of designing vaccines with traits that will minimize complications for immunization programs and increase the likelihood of successful adoption. The article also summarizes …

Author: Kristensen D, Zaffran M

Publication date: 2010

Desirable Attributes of Vaccines for Deployment in Low-Resource Settings

This article, published in the Journal of Pharmaceutical Sciences, discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including enhanced stability and efficient packaging, that can help to …

Author: Chen D, Zehrung D

Publication date: 2013

Development of a Fast-Dissolving Tablet Formulation of a Live Attenuated Enterotoxigenic E. coli Vaccine Candidate

A fast-dissolving tablet (FDT) that could be packaged in a compact stackable blister sheet is a potentially attractive option for formulating oral vaccines, since it would minimally impact the cold chain and could potentially be administered …

Author: Lal M, Priddy S, Bourgeois L, et al.

Publication date: 2013

Disposable-Syringe Jet Injectors

Jet injectors deliver vaccines and medicines without using needles. PATH has worked with several disposable-syringe jet injector developers to advance designs that are suitable and affordable for routine and campaign immunization programs in …

Author: PATH

Publication date: 2014

DNA Vaccine Delivery by Densely-Packed and Short Microprojection Arrays to Skin Protects Against Vaginal HSV-2 Challenge

This article, published in Vaccine, reports on a study that investigates the tolerability, immunogenicity, and efficacy of a plasmid DNA vaccine encoding the extracellular domain of gD2 using the Nanopatch™, a recently devised silicon …

Author: Kask AS, Chen X, Marshak JO, et al.

Publication date: 2010

Effect of Jet Injection on Infectivity of Measles, Mumps, and Rubella Vaccine in a Bench Model

This article, published in Vaccine, reports the results of a study that examined the effect of jet injection on the integrity of measles, mumps, and rubella vaccine (MMR), a live attenuated viral vaccine. The authors evaluated vaccine delivery via …

Author: Coughlin MM, Collins M, Saxon G, et al.

Publication date: 2015

Fractional Doses of Inactivated Poliovirus Vaccine in Oman

This article, published in The New England Journal of Medicine, reports on a clinical trial comparing fractional doses of inactivated poliovirus vaccine administered intradermally with full doses of vaccine given intramuscularly, with respect to …

Author: Mohammed AJ, AlAwaidy S, Bawikar S, et al.

Publication date: 2010

Giving Safe Injections: Using Auto-Disable Syringes for Immunization

This excellent, 112-page manual is a training curriculum for health care workers who provide injections. It includes information on the health impact of unsafe injections, selecting safe and effective vaccines, reconsituting vaccines safely, reading …

Author: PATH

Publication date: 2001

Guidelines for Implementing a National Procurement Policy to Integrate Safe-Injection Equipment

This report identifies key steps and information relevant to the development and implementation of a national procurement policy on safe-injection equipment, which includes safety devices for immunizations. The intention is to increase patient and …

Author: Making Medical Injections Safer

Publication date: 2010

Guidelines for National Strategies for the Safe and Appropriate Use of Injections

This two-page document summarizes key elements to assist in the development of a national strategy for ensuring safe and appropriate use of injections.

Author: World Health Organization

Publication date: 2000

Immunogenicity and Safety of Measles-Mumps-Rubella Vaccine Delivered by Disposable-Syringe Jet Injector in Healthy Brazilian Infants: A Randomized Non-Inferiority Study

This article, published in Contemporary Clinical Trials, reports on a study that compared the immunogenicity of the measles-mumps-rubella vaccine in infants when delivered by a disposable-syringe jet injector versus by needle and syringe. The …

Author: de Menezes Martins R, Curran B, de Lourdes Sousa Maia M, et al.

Publication date: 2015

The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine is Associated With the Size of the Intradermal Fluid Bleb

In response to the global shortage of inactivated poliovirus vaccine (IPV), the World Health Organization now recommends the use of fractional (one-fifth) intradermal doses of IPV (ID fIPV), both in campaigns and routine immunization schedules. This …

Author: Bibby J, Saidu Y, Umesi A, et al.

Publication date: 2017

Improving the Affordability of Inactivated Poliovirus Vaccines (IPV) for Use in Low- and Middle-Income Countries: An Economic Analysis of Strategies to Reduce the Cost of Routine IPV Immunization

This report presents results from an economic model that calculates the costs involved in delivering IPV vaccine in Indian immunization clinics according to three strategies: (1) intradermal delivery of reduced volumes of vaccine per dose, (2) use …

Author: PATH, Working in Tandem, Ltd.

Publication date: 2010

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