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Topic: Cold chain technologies

Total results with these characteristics: 106

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Above Zero: Strategies to Prevent Vaccine Freezing

This four-minute animated video emphasizes the difficulty and importance of maintaining proper temperatures in the vaccine cold chain. The risk of exposing vaccines to freezing temperatures are now known to be significant. These risks can be reduced …

Author: PATH, World Health Organization

Published: 2013

Achieving the Global Vision for Future Immunization Supply and Logistics Systems: Action Plans

These action plans describe specific activities and strategies designed to help achieve the common vision for the future of immunization supply systems developed by the Cold Chain and Logistics Task Force (led by the United Nations Children’s …

Author: World Health Organization, PATH

Published: 2012

Albania: Demonstrating the Benefits of an Online Immunization Registry

This document describes how project Optimize is collaborating with the Albanian Institute of Public Health to transform the way immunization data and vaccine stock are managed. The two-year collaboration aims to evaluate the benefits of a supply …

Author: PATH; World Health Organization

Published: 2012

Assessing the Potency of Oral Polio Vaccine Kept Outside of the Cold Chain During a National Immunization Campaign in Chad

This article, published in Vaccine, reports on a study of the potency of monovalent oral polio vaccine type 3 kept at ambient temperatures during a polio immunization campaign in Chad. The results of the study show that post-campaign laboratory …

Author: Zipursky S, Boualam L, Cheikh DO, et al.

Published: 2011

Assessment of a Remote Alarm System for Vaccine Storage in Albania

This report summarizes a study conducted between March and December 2010 to assess the marginal managerial advantages of using a global system for mobile communications/short message service messaging to transmit vaccine storage temperature data in …

Author: PATH, World Health Organization

Published: 2011

Care and Repair of Refrigerators for Vaccine Storage

This set of 17 training modules, developed for refrigerator technicians, includes handbooks on different types of refrigerators, as well as courses on service and repair techniques, repair work, and stocking spare parts, among others.

Author: World Health Organization

Characterization of a Thermostable Hepatitis B Vaccine Formulation

This article, published in the journal Vaccine, reports on the development of a new hepatitis B vaccine formulation that is stable against repeated freezing at -20°C and is also stable for 12 months at 37°C. The improved stability of this …

Author: Braun LJ, Jezek J, Peterson S, et al.

Published: 2009

Cold Chain and Logistics Management: An Essential Part of Safe and Effective Vaccination Programs

This fact sheet provides information on cold chain and logistics for vaccine delivery, including challenges for managing the cold chain, examples of effective cold chain management, and the costs associated with the cold chain.

Author: IMMUNIZATIONbasics

Published: 2008

Cold Chain Equipment Inventories

This fact sheet describes PATH’s work to develop and deploy a software tool called Cold Chain Equipment Manager to help vaccination programs manage equipment requirements, forecast equipment needs, and generate procurement lists. It includes a …

Author: PATH

Published: 2013

Cold Chain Equipment Manager

This tool is a Microsoft Access-based software tool that helps cold chain managers and public health officers make strategic decisions about managing their cold chain equipment. It is accompanied by a user manual, a set of data collection …

Author: PATH

Published: 2012

Cold Chain Technologies

This fact sheet describes PATH's work on cold chain technologies. PATH is working with manufacturers and country collaborators to advance passive cold chain equipment and refrigerators that keep vaccines cold without freezing, as well as solar …

Author: PATH

Published: 2013

Cold Chain Temperature Monitoring in Vietnam: Monitoring Ambient and Cold Chain Temperatures During Delivery of Human Papillomavirus Vaccine

This report summarizes findings from a temperature-monitoring study that gathered ambient temperature data during human papillomavirus (HPV) vaccine delivery in Vietnam. These data are compared to the known heat stability profile of the HPV vaccine …

Author: PATH, World Health Organization

Published: 2010

Collaborating With Countries to Improve Supply Chains

Optimize—a collaboration between the World Health Organization and PATH—aims to employ technological and scientific advances by defining ideal specifications for health products and creating a flexible and robust vaccine supply chain that can …

Author: PATH; World Health Organization

Published: 2010

Cool Innovations for Vaccine Transportation and Storage

Keeping heat-sensitive vaccines and other drugs at the right temperature is crucial yet often difficult in areas with limited or no electrical power. This fact sheet describes a response to this challenge, where a group of public- and private-sector …

Author: PATH, World Health Organization

Published: 2012

Delivering MenAfriVac Using the Controlled Temperature Chain Approach

In November 2012, the first immunization campaign to use a controlled temperature chain (CTC) took place in northern Benin. This photo set by project Optimize contains images taken during the campaign, where more than 155,000 people were vaccinated …

Author: PATH, World Health Organization

Published: 2013

Delivering Vaccines: A Cost Comparison of In-Country Vaccine Transport Container Options

Project Optimize undertook a cost-comparison case study of five container options for vaccine transport from the national to the regional level in Senegal. This report may be used as a starting point for other country vaccine programs weighing …

Author: PATH, World Health Organization

Published: 2013

Developing a Vision for Immunization Supply Systems in 2020: Landscape Analysis Summaries

Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses …

Author: PATH, World Health Organization

Published: 2011

Direct-Drive Solar Vaccine Refrigerators—A New Choice for Vaccine Storage

This evidence brief developed by project Optimize is directed toward supply chain managers in low- and middle-income countries and provides information about direct-drive solar refrigerators, which may be a good option for vaccine storage in areas …

Author: PATH, World Health Organization

Published: 2013

Domestic Refrigerators for Vaccine Storage in Tunisia: Conclusion and Recommendations

This project Optimize document summarizes a laboratory report on performance testing of four models of domestic refrigerators that are available on the Tunisian market. Project Optimize contracted the tests to demonstrate to the government the …

Author: PATH, World Health Organization

Published: 2012

Effectively Introducing a New Meningococcal A Conjugate Vaccine in Africa: The Burkina Faso Experience

In 2010, Burkina Faso conducted a country-wide campaign to introduce a new Group A meningococcal conjugate vaccine, MenAfriVac™. Leading up to this effort, the following challenges were successfully managed: (1) conducting a large safety study …

Author: Djingarey MH, Barry R, Bonkoungou M, et al.

Published: 2012

Effects of Freezing on Vaccine Potency: Literature Review

This document provides a literature review of articles about the effects of freezing on vaccine potency of hepatitis B, tetanus toxoid, diphtheria, and pertussis vaccines. Also included is a review of stability data of these vaccines at …

Author: PATH

Published: 2003

Evaluation of Out-of-the-cold-chain Approaches for Improving On-time Delivery of the Hepatitis B Birth Dose in Rural Areas of China

This document summarizes the results of a study of out-of-the-cold-chain approaches for improving on-time delivery of birth doses of the hepatitis B vaccine in rural areas of China. The study concluded that this is a safe and effective way to …

Author: PATH

Published: 2005

Evidence of Vaccine Freezing in the Cold Chain: Literature Review

This document provides a literature review of articles about evidence of vaccine freezing in the cold chain. The document is part of a series that describes the serious risk of freezing vaccines and World Health Organization-recommended …

Author: PATH

Published: 2003

Exposure to Heat and Freezing in the Vaccine Cold Chain in Thailand

Good cold chain practice is essential to maintain full immunogenicity of vaccines. This article, published in Vaccine, reports on a study that aimed to identify the likelihood and extent of exposure to inappropriate temperatures in the vaccine cold …

Author: Techathawat S, Varinsathien P, Rasdjarmrearnsook A, Tharmaphornpilas P

Published: 2006

Freeze-Protection of Aluminum-Adjuvanted Vaccines: PATH Formulation Technology

PATH has developed a low-cost and straightforward approach for protecting aluminum-adjuvanted vaccines from irreversible damage that results from freezing. Many current vaccines of importance to global health contain an aluminum-salt adjuvant (such …

Author: PATH

Published: 2014

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