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Beyond Eradication: The United States’ Role in Sustaining Public Health Gains Achieved Through Polio Programs

This report provides analysis and policy recommendations for the US government to protect the public health gains made as a result of polio eradication through technical and financial resources.

Author: PATH

Publication date: 2016

BID Initiative Briefs: Recommendations and Lessons Learned

In partnership with the governments of Tanzania and Zambia, the Better Immunization Data (BID) Initiative developed, tested, and rolled out interventions that address the most pressing routine immunization service delivery challenges, such as poor …

Author: PATH

Publication date: 2017

Biological Challenges and Technological Opportunities for Respiratory Syncytial Virus Vaccine Development

This article, published in Immunological Reviews, provides an overview of the barriers that have challenged and delayed the development of vaccines against respiratory syncytial virus (RSV) and identifies opportunities that could help overcome these …

Author: Graham B

Publication date: 2011

The Biological Function of Antibodies Induced by the RTS,S/AS01 Malaria Vaccine Candidate is Determined by Their Fine Specificity

This article, published in Malaria Journal, discusses how recent vaccine studies have shown that the magnitude of an antibody response is often insufficient to explain efficacy, suggesting that characteristics regarding the quality of the …

Author: Chaudhury S, Ockenhouse CF, Regules JA, et al.

Publication date: 2016

BioVentures for Global Health

BioVentures for Global Health (BVGH) is a nonprofit organization whose mission is to save lives by accelerating the development of novel biotechnology-based drugs, vaccines, and diagnostics to address the unmet medical needs of the developing world. …

Author: BioVentures for Global Health

The Bourgeoning Burden of Respiratory Syncytial Virus Among Children

This article, published in Infectious Disorders – Drug Targets, examines the disease burden of respiratory syncytial virus (RSV) in the United States, Canada, and Europe, but notes that the global burden of RSV is unknown as few studies are from …

Author: Hall CB

Publication date: 2012

Breakeven Analysis for Various Human Papillomavirus Vaccine Presentations in Vietnam and Uganda

This report highlights a study that uses a breakeven cost analysis to compare potential prices, wastage rates, and cold chain requirements for various human papillomavirus vaccine presentations. The results of this study provide insight into …

Author: PATH, World Health Organization

Publication date: 2010

Breaking the Cycle With Vaccines: The Malaria Life Cycle

This graphic displays the malaria parasite's life cycle and highlights where three different types of vaccines could interrupt various stages of the life cycle.

Author: PATH

Bringing Online Immunization Registries to Low-Resource Countries

Today, most health workers at the service‐delivery level in developing countries use paper‐based systems to track the individuals who have been vaccinated and the vaccines and other resources used during the process. This fact sheet describes …

Author: PATH, World Health Organization

Publication date: 2012

Broadening the Age Restriction for Initiating Rotavirus Vaccination in Regions With High Rotavirus Mortality: Benefits of Mortality Reduction Versus Risk of Fatal Intussusception

This article, published in Vaccine, reports on a study that assessed the potential benefits of mortality reduction versus the risk of fatal intussusception when (a) the first dose of rotavirus vaccine was administered by 12 weeks of age compared …

Author: Patel MM, Clark AD, Glass RI, et al.

Publication date: 2009

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein

Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …

Author: Mann B, Thornton J, Heath R, et al.

Publication date: 2013

A Broken Trust: Lessons from the Vaccine–Autism Wars

This article, published in PLoS Biology, discusses Sharon Kaufman's investigation into the forces fueling the growing divide between scientists and citizens, with the vaccine–autism link as her example. Kaufman aimed to …

Author: Gross L

Publication date: 2009

Building a Protected Sharps Barrel

This document explains how to correctly build a protected sharps barrel for the disposal of medical waste. It includes drawings to assist in construction.

Author: PATH

Publication date: 2006

Building a Protected Sharps Pit

This document explains how to correctly build a protected sharps pit for the disposal of medical waste. It includes drawings for two styles of sharps pits, MSF style and Indonesian style.

Author: PATH

Publication date: 2006

Building an Effective Malaria Vaccine Portfolio to Address Global Needs

This article, published in Vaccine, examines the research and development pipeline of malaria vaccines. It reviews the latest information on financing, vaccine commercialization, controlled human malaria infection models, and the regulatory …

Author: Birkett AJ

Publication date: 2015

Building Next Generation Immunization Supply Chains

This supplement to Vaccine contains 31 articles addressing the role of immunization supply chains (iSC) in expanding vaccine coverage, as well as current challenges, successful pilots, and innovative upstream solutions towards next-generation iSC. …

Author: Lee BY, Schreiber B, Rao R, eds.

Publication date: 2017

Building Next-Generation Vaccine Supply Systems: Supply Chain Modeling and Optimization

This fact sheet describes how Project Optimize—a collaboration between the World Health Organization and PATH—and their partners are working with countries to model the impact of changes to vaccine logistics and supply systems on vaccine …

Author: PATH, World Health Organization

Publication date: 2012

Burden and Aetiology of Diarrhoeal Disease in Infants and Young Children in Developing Countries (the Global Enteric Multicenter Study, GEMS): A Prospective, Case-Control Study

This article, published in The Lancet, reports on results of the Global Enteric Multicenter Study (GEMS), which was designed to identify the aetiology and population-based burden of pediatric diarrheal disease in sub-Saharan Africa and south Asia. …

Author: Kotloff KL, Nataro JP, Blackwelder WC, et al.

Publication date: 2013

The Burden of Childhood Pneumonia in the Developed World: A Review of the Literature

This article, published in The Pediatric Infectious Disease Journal, provides disease burden estimates of pneumonia incidence in the developed world in children under five years of age. Available estimates suggest that each year there are up to 2.6 …

Author: Madhi SA, Wals PD, Grijalva CG, et al.

Publication date: 2013

Burden of Disease and Circulating Serotypes of Rotavirus Infection in Sub-Saharan Africa: Systematic Review and Meta-analysis

To assess the potential impact of rotavirus vaccines in sub-Saharan Africa, researchers reviewed recent published data on rotavirus burden among children aged five years old and circulating serotypes in sub-Saharan Africa. Though many countries …

Author: Sanchez-Padilla E, Grais RF, Guerin PJ, et al.

Publication date: 2009

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