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Analysis of Strategies to Successfully Vaccinate Infants in Developing Countries Against Enterotoxigenic E. coli (ETEC) Disease

This article, published in Vaccine, outlines current candidates for a safe and effective vaccine against ETEC. The authors argue that a critical roadblock to achieving this goal has not been the science as much as the lack of a sufficiently funded …

Author: Walker RI, Steele D, Aguado T, Ad Hoc ETEC Technical Expert Committee

Publication date: 2007

Analysis of World Health Organization Policy Development Processes for a New Intervention: Malaria Vaccines

This document aims to elucidate the World Health Organization (WHO) process for developing policy guidelines for a malaria vaccine. The analysis considered past WHO recommendations on new interventions and assessed potential implications …

Author: PATH

Publication date: 2008

Andhra Pradesh: Building a Model Immunization System

This report discusses the work of PATH's Children's Vaccine Program and the Indian state of Andhra Pradesh to build a model immunization program, including the incorporation of hepatitis B vaccine into the childhood vaccination program.

Author: PATH

Publication date: 2004

Antibody Responses Among Adolescent Females Receiving the Quadrivalent HPV Vaccine Series Corresponding to Standard or Non-Standard Dosing Intervals

This article, published in Vaccine, reports on a study to assess antibody levels when dose 2 and/or dose 3 of the 3-dose quadrivalent human papillomavirus (HPV) vaccine were administered on schedule or delayed. The authors found that antibody …

Author: Russell K, Dunne E, Kemper AR, et al.

Publication date: 2015

Antibody-Independent Classical Pathway-Mediated Opsonophagocytosis of Type Ia, Group B Streptococcus

This article, published in The Journal of Clinical Investigation, elborates on experiements that indicate substances other than the exposed surface of the type Ia capsular polysaccharide initiate classical pathway-mediated opsonophagocytosis of …

Author: Baker CJ, Edwards MS, Webb BJ, Kasper DL

Publication date: 1982

Antibody-Independent, Interleukin-17A-Mediated, Cross-serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide

Published in the journal Infection and Immunity, this article shows that C-Ps given intranasally with mucosal adjuvant increased the resistance of mice to experimental nasopharyngeal colonization by capsulated S. pneumoniae of serotype 6B.

Author: Malley R, Srivastava A, Lipsitch M, et al.

Publication date: 2006

Anti-immunization Scare: The Inconvenient Facts

Dr. Steve Basser analyses the "quality of science of one particular, very public, opponent of immunisation--Dr. Vera Scheibner." Dr. Basser finds that "the gaps in her research...call into question her objectivity and cast doubts on …

Author: Basser S

Publication date: 1999

Apical Membrane Antigen 1: A Malaria Vaccine Candidate in Review

This article, published in Trends in Parasitology, presents the current understanding of apical membrane antigen 1 (AMA1), particularly in relation to the potential of AMA1 as a malaria vaccine and the approaches being taken toward clinical …

Author: Remarque EJ, Faber BW, Kocken CH, Thomas AW

Publication date: 2008

Architecture of Respiratory Syncytial Virus Revealed by Electron Cryotomography

This article, published in the Proceedings of the National Academy of Sciences of the United States of America, describes research to carry out an electron cryotomographic characterization of cell culture-grown human respiratory syncytial virus to …

Author: Liljeroos L, Krzyzaniak MA, Helenius A, Butcher SJ

Publication date: 2013

Artemisinin Resistance in Plasmodium falciparum Malaria

This study, published in the New England Journal of Medicine, compares the efficacies of two treatments--oral artesunate and artesunate followed by mefloquine--for uncomplicated falciparum malaria in Pailin, western Cambodia, and Wang Pha, …

Author: Dondorp AM, Nosten F, Yi P, et al.

Publication date: 2009

Ask the Experts

This web page provides clinical experts, including experts in immunization and infectious diseases, to answer parents' questions about diseases that affect their children.

Author: Parents of Kids with Infectious Diseases

Ask the Experts: Update on the Safety of Rotavirus Vaccines

This article, published by the American Pharmacists Association, addresses the safety of rotavirus vaccines, including the latest information on possible contamination issues. The authors indicate that the documented benefits of RotaTeq and …

Author: Mojica B, Hess K

Publication date: 2011

Assessing Disease Burden of JE: Population-Based Surveillance

This slide presentation provides an overview of the components of a population-based surveillance system for JE. The presentation should be used in conjunction with the World Health Organization's Recommended Standards for Surveillance of Selected …

Author: PATH

Publication date: 2008

Assessing the Potency of Oral Polio Vaccine Kept Outside of the Cold Chain During a National Immunization Campaign in Chad

This article, published in Vaccine, reports on a study of the potency of monovalent oral polio vaccine type 3 kept at ambient temperatures during a polio immunization campaign in Chad. The results of the study show that post-campaign laboratory …

Author: Zipursky S, Boualam L, Cheikh DO, et al.

Publication date: 2011

Assessing the Programmatic Suitability of Vaccine Candidates for WHO Prequalification (Revision 2014)

As part of the World Health Organization (WHO) vaccine prequalification (PQ) process, product summary files are assessed by the WHO PQ Secretariat to determine the suitability of the vaccine for the immunization services where it is intended to be …

Author: World Health Organization

Publication date: 2015

Assessing the Total Cost of Ownership for Cold Chain Equipment

Total cost of ownership refers to all costs associated with owning and operating a unit of equipment over its life expectancy. This tool is designed to assist decision-makers in evaluating available cold chain equipment options from a cost …

Author: PATH

Publication date: 2016

Assessment of a Remote Alarm System for Vaccine Storage in Albania

This report summarizes a study conducted between March and December 2010 to assess the marginal managerial advantages of using a global system for mobile communications/short message service messaging to transmit vaccine storage temperature data in …

Author: PATH, World Health Organization

Publication date: 2011

Assessment of Eight HPV Vaccination Programs Implemented in Lowest Income Countries

This article, published in BMC Public Health, reports results of a study that evaluated eight human papillomavirus (HPV) vaccination programs that were developed, implemented, and managed by local institutions in seven low-income countries as part …

Author: Ladner J, Besson M-H, Hampshire R, Tapert L, Chirenje M, Saba J

Publication date: 2012

An Assessment of Enterotoxigenic Escherichia coli and Shigella Vaccine Candidates for Infants and Children

This review article, published in Vaccine, describes the approaches to enterotoxigenic Escherichia coli (ETEC) and Shigella vaccines that are currently under development, including a range of both cellular and subunit approaches for each pathogen. …

Author: Walker RI

Publication date: 2015

Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo-Controlled, Randomized Double-Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine

This article, published in PLOS ONE, reports on the results of a double-blinded, randomized, placebo-controlled Phase 1 clinical trial of a cold-adapted and temperature-sensitive A/H7N3 live attenuated influenza vaccine candidate. The results of the …

Author: Rudenko L, Kiseleva I, Naykhin AN, et al.

Publication date: 2014

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