Published in the Bulletin of the World Health Organization, this article discusses the large role pneumonia plays in the deaths of children in the developing world and the need to address these deaths through the use of prevention and treatment …

Regulatory approval of diphtheria and tetanus toxoids and acellular pertussis (DTaP)-based combination vaccines containing Haemophilus influenzae type b (Hib) has been delayed in the United States because of difficulty in assessing the effect of …

Published in The Lancet Infectious Diseases, this article provides an overview of the diagnostic challenges of bacterial pneumonia and highlight the need for refining the current diagnostic approach to ensure adequate epidemiological surveillance of …

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …

Many junior doctors today have not had occasion to treat a child for Hib disease. The remarkable absence of cases of this disease is due to the use of conjugate vaccines. In countries with established Hib vaccination programs the incidence of …

This study, published in Bulletin of the World Health Organization, discusses the introduction of Hib vaccine in Kenya, one of the first nine countries to receive financial support from GAVI for Hib vaccine introduction. The objective of this study …

This paper, published in the Journal of Public Health, evaluates the cost-effectiveness of introducing Hib vaccine in Indonesia as an addition to the country's current DTP–Hepatitis B vaccination program.

Few Asian countries have introduced Haemophilus influenzae type b (Hib) conjugate vaccine because of its cost and uncertainty regarding disease burden. To estimate the effectiveness of Hib conjugate vaccine in preventing pneumonia and meningitis in …

This study, published in the Bulletin of the World Health Organization, used retrospective surveillance to identify cases of laboratory-diagnosed bacterial meningitis in Niamey, Niger, from 1981 to 1996. The study analyzed the cases …

This paper, published in the journal Vaccine, provides an up-to-date summary of the available epidemiological data regarding these pathogens in the Middle East and North Africa regions. In doing so, it highlights the need for additional …

To establish a relation between deaths due to acute respiratory infections (ARI) and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence …

Published in Epidemiological Reviews, this paper evaluates vaccines designed to prevent pneumonia among children in developing countries. Additionally, the article discusses the measurement of vaccine efficacy, as well as the potential of vaccine …

This fact sheet describes PATH's work in vaccines and immunization.

This document outlines a global action plan to support countries in controlling pneumonia, providing a framework for action around which partners can coordinate their efforts. The document summarizes the global situation with respect to pneumonia, …

Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. This study reviewed …

Designed for use by national public health officials and immunization programme managers, this position paper provides a summary of essential background information on Hib disease and vaccines and outlines the current WHO position concerning the …

A description of the disease, treatment interventions, and useful public health strategies. The web page also includes links to relevant WHO position papers and further references.

This document contains questions and answers designed to provide concise but comprehensive information on Haemophilus influenzae type b, bacteria which can cause serious childhood diseases, and the vaccines that protect against it.

This fact sheet provides information on Haemophilus influenzae type b (Hib) in Africa, including disease burden and prevention of the disease through the use of Hib vaccines.

This fact sheet provides information on Haemophilus influenzae type b (Hib) in Central Asia, including disease burden and prevention through the use of Hib vaccines.

This fact sheet provides information on Haemophilus influenzae type b (Hib) in South and South East Asia, including disease burden and prevention of the disease through the use of Hib vaccines.

This fact sheet provides information on Haemophilus influenzae type b (Hib) in the Eastern Mediterranean Region, including disease burden and the use of vaccines to prevent Hib.

This document outlines the introduction process for Hib conjugate vaccine into national immunization services. It offers a summary of WHO policies and practices regarding Hib immunization, and includes information on immunization strategies, …

This fact sheet provides information on Haemophilus influenza type b (Hib) in India, such as disease burden and recommendations for prevention of Hib, including the use of vaccines.