This article, from the Philosophical Transactions of the Royal Society B, examines recent efforts to accelerate the introduction of Haemophilus influenzae type b (Hib) vaccines in developing countries, which resulted in a significant surge in …

Published in the Bulletin of the World Health Organization, this article discusses the large role pneumonia plays in the deaths of children in the developing world and the need to address these deaths through the use of prevention and treatment …

Regulatory approval of diphtheria and tetanus toxoids and acellular pertussis (DTaP)-based combination vaccines containing Haemophilus influenzae type b (Hib) has been delayed in the United States because of difficulty in assessing the effect of …

Published in The Lancet Infectious Diseases, this article provides an overview of the diagnostic challenges of bacterial pneumonia and highlight the need for refining the current diagnostic approach to ensure adequate epidemiological surveillance of …

This report summarizes the objectives of PATH's now-inactive Children's Vaccine Program, highlighting the program's earlier activities in several countries in Africa and Asia aimed at increasing access to livesaving vaccines.

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …

Many junior doctors today have not had occasion to treat a child for Hib disease. The remarkable absence of cases of this disease is due to the use of conjugate vaccines. In countries with established Hib vaccination programs the incidence of …

This article, published in Vaccine, describes the development of a Haemophilus influenzae type b (Hib) conjugate vaccine at the National Institute for Public Health and the Environment/Netherlands Vaccine Institute (RIVM/NVI), and the subsequent …

This series of fact sheets describes symptoms of infection as well as the benefits and risk of vaccination for 14 diseases, including hepatitis B, Haemophilus influenzae type b, influenza, pneumococcal disease, polio, and rotavirus. There …

This study, published in Bulletin of the World Health Organization, discusses the introduction of Hib vaccine in Kenya, one of the first nine countries to receive financial support from GAVI for Hib vaccine introduction. The objective of this study …

This paper, published in the Journal of Public Health, evaluates the cost-effectiveness of introducing Hib vaccine in Indonesia as an addition to the country's current DTP–Hepatitis B vaccination program.

This article, published in The Lancet, focuses on the three most common causes of acute bacterial meningitis: Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis. The authors compare patterns of meningitis attributable to …

Few Asian countries have introduced Haemophilus influenzae type b (Hib) conjugate vaccine because of its cost and uncertainty regarding disease burden. To estimate the effectiveness of Hib conjugate vaccine in preventing pneumonia and meningitis in …

Routine immunization of infants in The Gambia with a Haemophilus influenzae type b (Hib) polysaccharide-tetanus toxoid conjugate vaccine began in May 1997. This article, published in The Lancet, reports on a study that investigated the effectiveness …

This study, published in the Bulletin of the World Health Organization, used retrospective surveillance to identify cases of laboratory-diagnosed bacterial meningitis in Niamey, Niger, from 1981 to 1996. The study analyzed the cases …

This web page provides an estimate of child mortality due to Haemophilus influenzae type b (Hib) and pneumococcal infections in 2008. It also contains a link to a chart of death rates due to these infections, broken down by region and HIV status.

To establish a relation between deaths due to acute respiratory infections (ARI) and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence …

This document outlines a global action plan to support countries in controlling pneumonia, providing a framework for action around which partners can coordinate their efforts. The document summarizes the global situation with respect to pneumonia, …

This user-friendly website provides extensive information about Haemophilus influenzae disease, including Haemophilus influenzae type b (Hib). It includes detailed information about the disease, surveillance, and vaccination, as well as links to …

Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. This study reviewed …

Designed for use by national public health officials and immunization programme managers, this position paper provides a summary of essential background information on Hib disease and vaccines and outlines the current WHO position concerning the …

A description of the disease, treatment interventions, and useful public health strategies. The web page also includes links to relevant WHO position papers and further references.

This page on the CDC website provides an overview of Hib disease and links and information on the Hib vaccine. The web page also has sections containing information especially geared for health professionals and the media.

This site offers information on vaccine and immunization programs at the American Academy of Pediatrics and includes video and text resources for parents. Resources include frequently asked questions for families, immunization information for …