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Total results with these characteristics: 34

Disease: Typhoid

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Accelerating Typhoid Conjugate Vaccine Introduction

This fact sheet describes the work and approach of the Typhoid Vaccine Acceleration Consortium (TyVAC), a partnership between the Center for Vaccine Development at the University of Maryland, the Oxford Vaccine Group at Oxford University, and PATH. …

Author: Typhoid Vaccine Acceleration Consortium

Publication date: 2017

The Burden of Typhoid Fever in Low- and Middle-Income Countries: A Meta-Regression Approach

This article, published in PLoS Neglected Tropical Diseases, provides an updated model-based estimate of the global burden of typhoid in low- and middle-income countries (LMICs). Model-based estimates were used to offer insights for decision-makers …

Author: Antillón M, Warren JL, Crawford FW, et al.

Publication date: 2017

Burden of Typhoid Fever in Low-Income and Middle-Income Countries: A Systematic, Literature-Based Update With Risk-Factor Adjustment

This article, published in The Lancet Global Health, reports the results of a study that aimed to estimate the burden of typhoid in low- and middle-income countries. The authors found that after adjusting for water-related risk, there was an …

Author: Mogasale V, Maskery B, Ochiai RL, et al.

Publication date: 2014

Center for Vaccine Innovation and Access

This website provides information about the work of PATH’s Center for Vaccine Innovation and Access, which brings together expertise across every stage of vaccine research, development, and introduction to make lifesaving vaccines globally …

Author: PATH

Coalition Against Typhoid

This website houses all resources, information, and advocacy materials from the Coalition against Typhoid (CaT), a global forum connecting researchers, advocates, and policymakers to raise awareness of typhoid, paratyphoid, and non-typhoidal …

Author: Sabin Vaccine Institute

Combination Vaccines Against Diarrheal Diseases

This article, published in Human Vaccines & Immunotherapeutics, outlines the need for the development of affordable and effective combination vaccines against diarrheal diseases. Despite the well-documented global burden of diarrheal diseases, …

Author: Venkatesan MM, Van de Verg LL

Publication date: 2015

Cost-Effectiveness Analysis of Typhoid Conjugate Vaccines in Five Endemic Low- and Middle-Income Settings

Typhoid fever remains endemic in low- and middle-income countries, yet programmatic use of existing vaccines is limited. This article, published in Vaccine, evaluates the cost-effectiveness of five typhoid conjugate vaccine (TCV) delivery strategies …

Author: Antillón M, Bilcke J, Paltiel AD, Pitzer VE

Publication date: 2017

Efficacy and Immunogenicity of a Vi-Tetanus Toxoid Conjugate Vaccine in the Prevention of Typhoid Fever Using a Controlled Human Infection Model of Salmonella Typhi: A Randomised Controlled, Phase 2b Trial

This article, published in The Lancet, reports the results of a study to assess the efficacy of a Vi-tetanus toxoid typhoid conjugate vaccine using a human challenge model of typhoid fever. The authors found the vaccine to be well tolerated, highly …

Author: Jin C, Gibani MM, Moore M, et al.

Publication date: 2017

Efficacy and Safety of Vi-Tetanus Toxoid Conjugated Typhoid Vaccine (PedaTyph™) in Indian Children: School Based Cluster Randomized Study

This article, published in Human Vaccines & Immunotherapeutics, reports the results of a study that evaluated the safety and efficacy of a typhoid conjugate vaccine in children 6 months to 12 years of age. The authors found that the vaccine was …

Author: Mitra M, Shah N, Ghosh A, et al.

Publication date: 2016

A Forecast of Typhoid Conjugate Vaccine Introduction and Demand in Typhoid Endemic Low- and Middle-Income Countries to Support Vaccine Introduction Policy and Decisions

This article, published in Human Vaccines & Immunotherapeutics, describes the results of a demand forecast for the typhoid conjugate vaccine (TCV) that includes introduction dates for countries based on specific criteria and estimated vaccine …

Author: Mogasale V, Ramani E, Park IY, Lee JS

Publication date: 2017

Global Advisory Committee on Vaccine Safety, 30 November – 1 December 2016: Safety of Typhoid Vaccines

This article, published in the Weekly Epidemiological Record, reports the outcome of a meeting of the World Health Organization’s independent vaccine safety committee where they reviewed the current safety data of three generations of typhoid …

Author: World Health Organization

Publication date: 2017

Global Burden of Disease

The Global Burden of Disease Study is the most comprehensive global observational epidemiological study to date. It describes mortality and morbidity from major diseases, injuries, and risk factors to health at the global, national, and regional …

Author: Global Burden of Disease Study Collaborators

The Global Burden of Typhoid Fever

This article, published in the Bulletin of the World Health Organization, summarizes the findings of a literature search of population-based studies using confirmation by blood culture of typhoid fever cases. The authors estimated that, in the year …

Author: Crump JA, Luby SP, Mintz ED

Publication date: 2004

High Rates of Enteric Fever Diagnosis and Lower Burden of Culture-Confirmed Disease in Peri-Urban and Rural Nepal

Existing data on enteric fever in South Asia is mostly derived from urban areas. This article, published in the Journal of Infectious Diseases, characterizes enteric disease diagnosis, treatment practices, and the true burden of enteric fever among …

Author: Andrews JR, Vaidya K, Bern C, et al.

Publication date: 2017

Immunization Matters

This quarterly e-newsletter provides updates from PATH’s Center for Vaccine Innovation and Access on late-stage and licensed vaccines included in its portfolio as well as its work on health economics and optimization, operations research, and …

Author: PATH

Incidence of Invasive Salmonella Disease in Sub-Saharan Africa: A Multicentre Population-Based Surveillance Study

This article, published in The Lancet Global Health, reports the results of a study that aimed to measure incidence estimates of typhoid fever and invasive non-typhoidal salmonella (iNTS) disease in sub-Saharan Africa. Using data from 13 African …

Author: Marks F, von Kalckreuth V, Aaby P, et al.

Publication date: 2017

Policymakers Views Regarding the Introduction of New-Generation Vaccines Against Typhoid Fever, Shigellosis, and Cholera in Asia

Published in Vaccine, this article disusses face-to-face interviews and meetings with more than 160 policymakers and other influential professionals in seven large Asian countries (Bangladesh, China, India, Indonesia, Pakistan, Thailand and …

Author: DeRoeck D, Clemens JD, Nyamete A, Mahoney RT

Publication date: 2005

Rethinking Typhoid Fever Vaccines: Implications for Travelers and People Living in Highly Endemic Areas

This article, published in the Journal of Travel Medicine, summarizes evidence about the efficacy, delivery, and impact of current typhoid vaccines and the potential for new typhoid conjugate vaccines or improved live oral vaccines to protect young …

Author: Whitaker JA, Franco-Paredes C, Del Rio C, Edupuganti S

Publication date: 2009

Revisiting Typhoid Fever Surveillance in Low and Middle Income Countries: Lessons From Systematic Literature Review of Population-Based Longitudinal Studies

This article, published in BMC Infectious Diseases, reports the results of a systematic literature review of longitudinal population-based blood culture-confirmed typhoid fever studies from low- and middle-income countries. The reported incidence …

Author: Mogasale V, Mogasale VV, Ramani E, et al.

Publication date: 2016

Safety and Immunogenicity of a Vi Polysaccharide–Tetanus Toxoid Conjugate Vaccine (Typbar-TCV) in Healthy Infants, Children, and Adults in Typhoid Endemic Areas: A Multicenter, 2-Cohort, Open-Label, Double-Blind, Randomized Controlled Phase 3 Study

This article, published in Clinical Infectious Diseases, reports the results of a study examining the safety and efficacy of a typhoid conjugate vaccine in people aged 6 months to 24 years conducted at eight trial sites in India. The results showed …

Author: Mohan VK, Varanasi V, Singh A, et al.

Publication date: 2015

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