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Disease: Rotavirus

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Progress With the Implementation of Rotavirus Surveillance and Vaccines in Countries of the WHO African Region, 2007–2016

This article, published in the Weekly Epidemiological Record, summarizes progress made in rotavirus vaccine implementation in Africa following the World Health Organization's (WHO's) 2009 recommendation for routine childhood rotavirus vaccination …

Author: Mwenda JM, Burke RM, Shaba K, et al.

Publication date: 2017

Projected Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries: 2011–2030

This article, published in Vaccine, projects the cost-effectiveness and health impact of rotavirus vaccines in countries eligible for support from the GAVI Alliance. The authors used a decision-analytic model to project the health outcomes and …

Author: Atherly DE, Lewis KDC, Tate J, Parashar UD, Rheingans RD

Publication date: 2012

Projected Health Benefits and Costs of Pneumococcal and Rotavirus Vaccination in Uganda

The authors of this article, published in Vaccine, determined the impact and cost-effectiveness of pneumococcal and rotavirus vaccination programs among children younge than five years of age in Uganda from the public health system perspective. They …

Author: Tate JE, Kisakye A, Mugyenyi P, Kizza D, Odiit A, Braka F

Publication date: 2011

Projected Impact and Cost-Effectiveness of a Rotavirus Vaccination Program in India, 2008

The authors of this article, published in Clinical Infectious Diseases, aimed to determine the potential impact and cost-effectiveness of a national rotavirus vaccination program in India. They compared the national rotavirus disease and cost burden …

Author: Esposito DH, Tate JE, Kang G, Parashar UD

Publication date: 2011

Projecting the Effectiveness of RotaTeq® Against Rotavirus-Related Hospitalizations and Deaths in Six Asian Countries

This article, published in Human Vaccines, describes the projected effectiveness of RotaTeq®, which is an oral pentavalent rotavirus vaccine (RV5), against rotavirus gastroenteritis (RGE)-related hospitalizations and deaths in six Asian …

Author: El Khoury AC, Mast TC, Ciarlet M, Markson LE, Goveia MG

Publication date: 2011

Protecting Aluminum-Adjuvanted Vaccines From Freeze Damage

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global health …

Author: PATH

Publication date: 2012

Protecting Children From Diarrheal Disease: PATH Takes a Comprehensive Approach to Combating This Leading Cause of Child Deaths

This fact sheet provides an overview of PATH's work, including vaccine development and introduction, in protecting children from diarrheal disease.

Author: PATH

Publication date: 2015

Protection Against Gastroenteritis in US Households With Children Who Received Rotavirus Vaccine

This study, published in the Journal of Infectious Diseases, compared gastroenteritis rates among households in the United States whose child had received rotavirus vaccine with those whose child did not receive the vaccine. The results showed …

Author: Cortese MM, Dahl RM, Curns AT, Parashar UD

Publication date: 2014

Protective Association Between Rotavirus Vaccination and Childhood Seizures in the Year Following Vaccination in US Children

This article, published in Clinical Infectious Diseases, describes a review of data from 250,000 children born in the United States between March 2006—when rotavirus vaccines were introduced in the United States—and November 2009 for incidences …

Author: Payne DC, Baggs J, Zerr DM, et al.

Publication date: 2013

Public Finance of Rotavirus Vaccination in India and Ethiopia: An Extended Cost-Effectiveness Analysis

This article, published in Vaccine, reports on a study that evaluated the potential impact of a publicly funded national rotavirus vaccination program in India and Ethiopia on reducing deaths and household costs due to rotavirus disease. The authors …

Author: Verguet S, Murphy S, Anderson B, Johansson KA, Glass R, Rheingans R

Publication date: 2013

PubMed Searches: Rotavirus

These pre-formatted PubMed searches will retrieve journal citations and available abstracts that address relevant issues related to rotavirus. Documents may be ordered through Loansome Doc if you have established an agreement with a participating …

Author: Various

A Randomized Controlled Trial of the Impact of Alternative Dosing Schedules on the Immune Response to Human Rotavirus Vaccine in Rural Ghanaian Infants

This article, published in the Journal of Infectious Diseases, presents the findings of a randomized trial in rural Ghana that compared anti-rotavirus immune responses to the two-dose monovalent human rotavirus vaccine when administered at ages 6/10 …

Author: Armah G, Lewis KDC, Cortese MM, et al.

Publication date: 2016

A Randomized Phase III Clinical Trial to Assess the Efficacy of a Bovine-Human Reassortant Pentavalent Rotavirus Vaccine in Indian Infants

This article, published in Vaccine, reports the results of a Phase 3 clinical efficacy trial of a new vaccine against the five most common strains of rotavirus. The study, which was conducted at six study sites across India, showed the vaccine to be …

Author: Kulkarni PS, Desai S, Tewari T, et al.

Publication date: 2017

R&D for Diarrhoeal Diseases

While preventive measures such as clean drinking water and sanitation can reduce the risk of infection from diarrheal diseases, research and development (R&D) of new tools is equally important, particularly for vaccines as they can prevent …

Author: Policy Cures

Publication date: 2013

Real World Impact of Rotavirus Vaccination

This special supplement of the Pediatric Infectious Disease Journal presents a collection of studies on the impact of rotavirus vaccines. The data demonstrate dramatic and rapid reductions in childhood hospitalizations in several countries after …

Author: Patel MM, Parashar UD, eds.

Publication date: 2011

Record of the Meeting of the Advisory Committee on Immunization Practices, February 21-22, 2006

The meeting report outlines the committee's recommendations for introduction of RotaTeq® into the routine US immunization schedule and provides guidance on addressing special circumstances in relation to administration of the vaccine. The document …

Author: US Centers for Disease Control and Prevention

Publication date: 2006

Reduced Price on Rotavirus Vaccines: Enough to Facilitate Access Where Most Needed?

This article, published in the Bulletin of the World Health Organization, examines whether the reduced prices for rotavirus vaccine are affordable enough to facilitate access to the vaccine where it is most needed. The study points to the rotavirus …

Author: Madsen LB, Ustrup M, Fischer TK, Bygbjerg IC, Konradsen F

Publication date: 2012

Refocusing Gavi for Greater Impact

This report outlines the large impact that Gavi, the Vaccine Alliance, has had on immunization rates in eligible countries through funding support and dispersal of vaccines. It also provides recommendations on how Gavi could have a greater impact. …

Author: Dykstra S, Glassman A, Kenny C, Sandefur J (Center for Global Development)

Publication date: 2015

Removing the Age Restrictions for Rotavirus Vaccination: A Benefit-Risk Modeling Analysis

This article, published in PLOS Medicine, reports on a study that analyzed the benefits and risks of relaxing the vaccine dosing age restrictions for rotavirus vaccines and concluded that the lives of nearly 50,000 additional children in low- and …

Author: Patel MM, Clark AD, Sanderson CFB, Tate J, Parashar UD

Publication date: 2012

The Right Shot: Bringing Down Barriers to Affordable and Adapted Vaccines - 2nd Edition

This second edition of The Right Shot gathers more than 1,500 data points from organizations including UNICEF, the Pan-American Health Organization, governments, vaccine manufacturers, and Médecins Sans Frontières' supply centers to better …

Author: Médecins Sans Frontières

Publication date: 2015

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